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John D. Crispino, PhD MBA
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Journal Articles

DYRK1A Is Regulated By Oncogenic KMT2A and Required for Survival of KMT2A -Rearranged Acute Lymphoblastic Leukemia

Christian Hurtz, PhD, Gerald Wertheim, MD, PhD, Rahul S. Bhansali, Anne Lehman, Grace Jeschke, PhD, John D. Crispino, PhD MBA, Thierry Besson, PhD, Sarah K. Tasian, MD, Martin Carroll, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2742.
https://doi.org/10.1182/blood-2019-123475
Published: 2019
Journal Articles

FBXO11 Is a Candidate Tumor Suppressor in the Transformation of MDS to Secondary AML

Michael Schieber, MD, John D. Crispino, PhD MBA
Journal: Blood
Blood (2019) 134 (Supplement_1): 4217.
https://doi.org/10.1182/blood-2019-124007
Published: 2019
Journal Articles

The Chromosome 21 Kinase DYRK1A and Its Substrate FOXO1 Constitute a Novel Therapeutic Pathway in B-ALL

Rahul S. Bhansali, Malini Rammohan, MS, Ji Heon Paul Lee, MD PhD, Sebastien Malinge, PhD, Yi-Chien Tsai, Nobuko Hijiya, MD, Beat Bornhauser, PhD, Jean-Pierre Bourquin, MD PhD, Corinne Fruit, Thierry Besson, PhD, John D. Crispino, PhD MBA
Journal: Blood
Blood (2018) 132 (Supplement 1): 548.
https://doi.org/10.1182/blood-2018-99-119854
Published: 2018
Journal Articles

Alisertib (MLN8237), an Oral Selective Inhibitor of Aurora Kinase a, Has Clinical Activity and Restores GATA1 Expression in Patients with Myelofibrosis

Naseema Gangat, MBBS, Brady Lee Stein, MD, Christian Marinaccio, Ronan Swords, MD PhD, Justin M. Watts, MD, Sandeep Gurbuxani, Olga Frankfurt, MD, Jessica K. Altman, MD, Jeremy Q. Wen, MD PhD, Noushin Farnoud, PhD, Christopher Famulare, MS, Akshar Patel, BA, Roberto Tapia, BS, Amy Handlogten, Yvonne Trang Dinh, BS, Kristen Englund, Shradha Patel, Juan Carlos Nobrega, Dalissa Tejera, MSN, Amber Thomassen, Harald Stein, MD PhD Dr. h.c., Juehua Gao, MD PhD, Peng Ji, MDPhD, Raajit K. Rampal, MD PhD, Francis J. Giles, MD FRCPI, FRCPath, Ayalew Tefferi, MD, John D. Crispino, PhD MBA
Journal: Blood
Blood (2018) 132 (Supplement 1): 688.
https://doi.org/10.1182/blood-2018-99-110381
Published: 2018
Journal Articles

STAT3 Is Activated By DYRK1A and Is a Potential Therapeutic Target in B-ALL

Malini Rammohan, MS, Rahul S. Bhansali, Yi-Chien Tsai, Alexander Dong, Sebastien Malinge, PhD, Jean-Pierre Bourquin, MD PhD, John D. Crispino, PhD MBA
Journal: Blood
Blood (2018) 132 (Supplement 1): 3898.
https://doi.org/10.1182/blood-2018-99-115429
Published: 2018
Journal Articles

Modelling the Progression of a Preleukemic Stage to Overt Leukemia in Children with Down Syndrome

Maurice Labuhn, MSc, Kelly Perkins, PhD, Elli Papaemmanuil, PhD, Catherine Garnett, Soeren Matzk, Vyacheslav Amstislavskiy, Marlen Metzner, Alison Kennedy, Carina Scheer, Kenichi Yoshida, MD PhD, Adrian Schwarzer, MD PhD, John D. Crispino, PhD MBA, Jeffrey W. Taub, MD, Mitchell J. Weiss, MD PhD, Etsuro Ito, MDPhD, Seishi Ogawa, MD PhD, Dirk Reinhardt, Marie-Laure Yaspo, PhD, Peter J. Campbell, PhD, Dirk Heckl, PhD, Jan-Henning Klusmann, Paresh Vyas
Journal: Blood
Blood (2018) 132 (Supplement 1): 543.
https://doi.org/10.1182/blood-2018-99-116661
Published: 2018
Journal Articles

Global Chromatin Occupancy and Epigenetic Signature Analysis Reveal New Insights into the Function of GATA1 N-Terminus in Erythropoiesis

Te Ling, PhD, Yehudit Birger, PhD, Monika Stankiewicz, PhD, Nissim Ben-Haim, Itamar Kanter, Tomer Kalisky, Avigail Rein Gil, MD, Neil L Kelleher, PhD, Lihua Zou, PhD, Shai Izraeli, MD, John D. Crispino, PhD MBA
Journal: Blood
Blood (2018) 132 (Supplement 1): 533.
https://doi.org/10.1182/blood-2018-99-115338
Published: 2018
Journal Articles

Dynamins 2 and 3 Are Required for Human Megakaryocytes Directional Migration

Praveen K Suraneni, PhD, Seth J. Corey, MD, Michael Hession, BS, Rameez Ishaq, Arinola Awomolo, Shirin Hasan, PhD, Najet Debili, PhD, John D. Crispino, PhD MBA, Elizabeth A. Eklund, MD, Yolande Chen, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2429.
https://doi.org/10.1182/blood-2018-99-118782
Published: 2018