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Joao T Barata, PhD
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Journal Articles

The JAK Inhibitor Ruxolitinib Is Effective in Treating T Cell Acute Lymphoblastic Leukemia with Gain of Function Mutations in IL-7R Alpha

Emilee Senkevitch, PhD BS, Julie Hixon, Caroline Andrews, Joao T Barata, PhD, Wenqing Li, Scott Durum
Journal: Blood
Blood (2015) 126 (23): 1330.
https://doi.org/10.1182/blood.V126.23.1330.1330
Published: 2015
Journal Articles

Bone Marrow Stroma Protects BCR-ABL-Negative Myeloproliferative Neoplasms from Ruxolitinib- and Vorinostat-Induced Apoptosis

Bruno A Cardoso, PhD, Helio Belo, MSc, Ana Isabel Oliveira, MSc, Olga Pereira, MSc, Joao T Barata, PhD, Antonio Almeida, MD PhD
Journal: Blood
Blood (2014) 124 (21): 910.
https://doi.org/10.1182/blood.V124.21.910.910
Published: 2014
Journal Articles

CK2 Basal Activity Regulates IL-7-Mediated JAK/STAT and PI3K/Akt Pathway Activation and Pro-Survival Effects in T-Cell Acute Lymphoblastic Leukemia Cells

Alice Melao, Ana Girio, PhD, Joao T. Barata, PhD
Journal: Blood
Blood (2012) 120 (21): 1242.
https://doi.org/10.1182/blood.V120.21.1242.1242
Published: 2012
Journal Articles

The Role of IL7R in the Induction and Maintenance of T-Cell Leukemia/Lymphoma in Vivo

Ana Silva, PhD, Joao T. Barata, PhD, Benedict Seddon, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 116.
https://doi.org/10.1182/blood.V120.21.116.116
Published: 2012
Journal Articles

STAT5 Activation Is Mandatory for IL-7-Mediated Viability and Growth of T-Cell Acute Lymphoblastic Leukemia Cells

Daniel Ribeiro, Ana Silva, PhD, Bruno A. Cardoso, PhD, Joao T. Barata, PhD
Journal: Blood
Blood (2012) 120 (21): 3530.
https://doi.org/10.1182/blood.V120.21.3530.3530
Published: 2012
Journal Articles

In Vitro and in Vivo Targeting of Chronic Lymphocytic Leukemia Using CX-4945, a Clinical-Stage CK2-Specific Inhibitor.

Leila R. Martins, DVM, Paulo Lúcio, MD, PhD, Alice Melao, Bruno A. Cardoso, PhD, Ryan Stansfield, Denis Drygin, PhD, Maria Gomes Silva, MD, PhD, Joao T. Barata, PhD
Journal: Blood
Blood (2012) 120 (21): 2897.
https://doi.org/10.1182/blood.V120.21.2897.2897
Published: 2012
Journal Articles

Targeting CK2 Overexpression as a Novel Therapeutic Tool in Chronic Lymphocytic Leukemia.

Leila R. Martins, Paulo Lúcio, MD, PhD, Paula Gameiro, MD, Maria Gomes Silva, MD, PhD, Joao T Barata, PhD
Journal: Blood
Blood (2009) 114 (22): 803.
https://doi.org/10.1182/blood.V114.22.803.803
Published: 2009
Journal Articles

mTOR as Therapeutic Target for T-Cell Leukemia: Synergism with Conventional Cytotoxic Drugs and Signaling Inhibitors.

Ana Batista, MSc, Joao T. Barata, PhD, Lara F. Costa, Stephen E. Sallan, MD, Nadia Carlesso, MD, PhD, Lee M. Nadler, MD, Angelo A. Cardoso, MD, PhD
Journal: Blood
Blood (2004) 104 (11): 521.
https://doi.org/10.1182/blood.V104.11.521.521
Published: 2004
Journal Articles

Crosstalk between Breast Cancer Cells and Bone Marrow Endothelium Require the Engagement of PI3K/AKT Signaling.

Joana G. Brandao, Joao T. Barata, PhD, Raquel Nunes, MD, Lee M. Nadler, MD, Angelo A. Cardoso, MD, PhD
Journal: Blood
Blood (2004) 104 (11): 1299.
https://doi.org/10.1182/blood.V104.11.1299.1299
Published: 2004