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Jayne S. Danska, PhD
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Journal Articles

Sirpαfc Treatment Targets Human Acute Myeloid Leukemia Stem Cells

Oleksandr Galkin, PhD, Jessica McLeod, BSc, James A Kennedy, MD PhD, Liqing Jin, MD, Nathan Mbong, Mark Wong, PhD, Bob Uger, PhD, Mark D. Minden, MD PhD, Jayne S Danska, PhD, Jean C.Y. Wang, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3906.
https://doi.org/10.1182/blood-2019-131018
Published: 2019
Journal Articles

Genetic Analysis of B-Cell Acute Lymphoblastic Leukemia Dissemination to the Central Nervous System Identifies Clonal Selection and Therapeutic Vulnerability

Robert Vanner, MD PhD, Stephanie M. Dobson, PhD, Ildiko Grandal, MSc, Olga I. Gan, PhD, Jessica McLeod, BSc, James Kennedy, MD PhD, Veronique Voisin, PhD, Cynthia Guidos, PhD, Jayne S. Danska, PhD, Esme Waanders, PhD, Mark D. Minden, MD PhD, Charles G. Mullighan, MBBS, MD, John E. Dick, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1542.
https://doi.org/10.1182/blood-2018-99-115191
Published: 2018
Journal Articles

RANK-RANKL Mediated Bone Destruction in B-Cell Acute Lymphoblastic Leukemia

Sujeetha A. Rajakumar, MSc, Eniko Papp, PhD, Ildiko Grandal, MSc, Daniele Merico, PhD, Careesa C. Liu, MSc, Bedilu Allo, PhD, Lucia Zhang, Marc Grynpas, PhD, Mark D. Minden, MD PhD, Johann K. Hitzler, MD, Cynthia J. Guidos, PhD, Jayne S. Danska, PhD
Journal: Blood
Blood (2016) 128 (22): 908.
https://doi.org/10.1182/blood.V128.22.908.908
Published: 2016
Journal Articles

Linking Subclonal Genetic Diversity with Functional Heterogeneity Identifies Diagnosis Subclones Destined to Relapse

Stephanie M. Dobson, Esme Waanders, PhD, Robert Vanner, PhD, Olga I Gan, PhD, Jessica McLeod, Ildiko Grandal, MSc, Debbie Payne-Turner, BA, Michael Edmonson, PhD, Zhaohui Gu, PhD, Xiaotu Ma, PhD, Yiping Fan, Sagi Abelson, PhD, Pankaj Gupta, Michael Rusch, Ying Shao, Lei Shi, PhD, Stanley Pounds, PhD, Scott Olsen, Geoffrey A. Neale, PhD, John Easton, PhD, Cynthia J. Guidos, PhD, Jayne S. Danska, PhD, Jinghui Zhang, PhD, Mark D. Minden, MD PhD, Charles G. Mullighan, MBBS(Hons), MSc, MD, John E. Dick, PhD
Journal: Blood
Blood (2016) 128 (22): 605.
https://doi.org/10.1182/blood.V128.22.605.605
Published: 2016
Journal Articles

Blockade Of CD47 Using SIRPαFc: Role Of The Fc Region In Anti-Leukemic Activity and Tolerability

Robert A. Uger, PhD, Xinli Pang, MD, PhD, Mark Wong, PhD, Violetta House, Karen Dodge, Stephane Viau, Noel T. Vigo, Debbie Tam, Tran Truong, Liqing Jin, MD, Andrei V. Malko, Jenny Ho, MD, Tatiana K. Prasolava, PhD, Jayne S. Danska, PhD, Jean C.Y. Wang, MD PhD, Penka S. Petrova, PhD
Journal: Blood
Blood (2013) 122 (21): 3935.
https://doi.org/10.1182/blood.V122.21.3935.3935
Published: 2013
Journal Articles

Defining Functional Heterogeneity In Acute Lymphoblastic Leukemia

Stephanie M. Dobson, BSc, Esmé Waanders, PhD, Jessica McLeod, Ildiko Grandal, Olga I. Gan, PhD, Faiyaz Notta, PhD, Jessica Loo-Young-Kee, Mark D. Minden, MD PhD, Cynthia J. Guidos, PhD, Jayne S. Danska, PhD, Charles G. Mullighan, MBBS, MSc, MD, FRACP, FRCPA, John E. Dick, PhD
Journal: Blood
Blood (2013) 122 (21): 1365.
https://doi.org/10.1182/blood.V122.21.1365.1365
Published: 2013
Journal Articles

A Novel Mutational Mechanism Drives Over-Expression of Ligand-Independent FLT3 in a Murine Model of B-Precursor ALL

Radia Johnson, Eniko Papp, Ildiko Grandal, Paul Kowalski, PhD, Peggy PC Wong, MD, FRCPC, M.Sc., Jayne S. Danska, PhD, Cynthia Guidos, PhD
Journal: Blood
Blood (2011) 118 (21): 640.
https://doi.org/10.1182/blood.V118.21.640.640
Published: 2011
Journal Articles

Acute Myeloid Leukemia Stem Cells Escape Innate Immune Surveillance by Macrophages through Interaction with SIRPα

Alexandre P.A. Theocharides, MD, Liqing Jin, MD, Po-Yan Cheng, Armando G. Poeppl, Tatiana K. Prasolava, PhD, Mark D. Minden, MD, PhD, John E. Dick, PhD, Jayne S. Danska, PhD, Jean C.Y. Wang, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 499.
https://doi.org/10.1182/blood.V116.21.499.499
Published: 2010
Journal Articles

Leukemic and Normal Stem Cell Transcriptional Signatures Determined by Functional Assays Are Predictive of the Overall Survival of AML Patients.

Kolja Eppert, MSc, PhD, Katsuto Takenaka, MD, Björn Nilsson, M.D., Ph.D., Eric R Lechman, M.Sc., Ph.D., Vicki Ling, MSc, Joseph Beyene, PhD, Angelo J Canty, PhD, Jayne S Danska, PhD, Mark D Minden, MD, Todd R. Golub, MD, Benjamin L Ebert, MD, PhD, John E Dick, PhD
Journal: Blood
Blood (2009) 114 (22): 389.
https://doi.org/10.1182/blood.V114.22.389.389
Published: 2009
Journal Articles

CD47-Sirpα Interaction Modulates Homing and Engraftment of Human Acute Myeloid Leukemia Stem Cells in Mice.

Alexandre PA Theocharides, MD, Liqing Jin, MD, Armando G Poeppl, Tatiana K Prasolava, PhD, Olga I Gan, PhD, Mark D Minden, MD, PhD, Jayne S Danska, PhD, John E Dick, PhD, Jean CY Wang, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 476.
https://doi.org/10.1182/blood.V114.22.476.476
Published: 2009
Journal Articles

Role of Spleen Tyrosine Kinase Signaling in Early B Cell Acute Lymphoblastic Leukemia.

Tatiana Perova, MSc, Lauryl Nutter, PhD, Irina Matei, PhD, Ildiko Grandal, MSc, Polly Pine, Yasumichi Hitoshi, PhD, Johann K. Hitzler, MD, Cynthia J Guidos, PhD, Jayne S Danska, PhD
Journal: Blood
Blood (2009) 114 (22): 3092.
https://doi.org/10.1182/blood.V114.22.3092.3092
Published: 2009
Journal Articles

Human SIRPA Polymorphism Modulates Macrophage-Mediated Suppression of Human Hematopoiesis

Takuro Kuriyama, M.D., Katsuto Takenaka, M.D., PhD, Takashi Kumano, M.D., Seido Oku, MD, Shingo Urata, M.D., Koji Nagafuji, MD, PhD, John E. Dick, PhD, Jayne S Danska, PhD, Koichi Akashi, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 3485.
https://doi.org/10.1182/blood.V112.11.3485.3485
Published: 2008
Journal Articles

Identification of a New Genetic Determinant Controlling Human Hematopoietic Stem Cell Engraftment.

Katsuto Takenaka, MD, PhD, Tatiana K. Prasolava, PhD, Jean C.Y. Wang, MD PhD, Steven M. Mortin-Toth, Sam Khalouei, Olga I. Gan, PhD, John E. Dick, PhD, Jayne S. Danska, PhD
Journal: Blood
Blood (2007) 110 (11): 175.
https://doi.org/10.1182/blood.V110.11.175.175
Published: 2007