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Jay L. Hess, MD PhD
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Journal Articles

The Role of STAT5 in HOXA9-Associated Leukemia

Peilin Ma, MD, PhD, Yuqing Sun, MS, Jingya Wang, PhD, Weihua Song, MD, PhD, Tao Xu, PhD, Reuben Kapur, PhD, Jay L. Hess, MD PhD
Journal: Blood
Blood (2016) 128 (22): 3919.
https://doi.org/10.1182/blood.V128.22.3919.3919
Published: 2016
Journal Articles

Pathways Relevant to AML Pathogenesis Targeting the Hematopoietic-Specific Cebpa +37 Kb Enhancer

Stacy Cooper, MD, Hong Guo, MD PhD, Justin Thomas, Jay L. Hess, MD PhD, Peter D. Aplan, MD, Donald Small, MD PhD, Alan D. Friedman, MD
Journal: Blood
Blood (2016) 128 (22): 2691.
https://doi.org/10.1182/blood.V128.22.2691.2691
Published: 2016
Journal Articles

Characterization of the Molecular Interplay Between HOXA9 and Ogt in Leukemia

Jean-Francois M Rual, PhD, Tao Xu, PhD, Cailin Collins, Honglai Zhang, PhD, Jingya Wang, Rork Kuick, MS, Joel Bronstein, Venkatesha Basrur, PhD, Sung Soo Park, PhD, Kim Ha, Lili Chen, Kojo S.J. Elenitoba-Johnson, MD, Andrew G. Muntean, PhD, Jay L. Hess, MD PhD
Journal: Blood
Blood (2014) 124 (21): 3533.
https://doi.org/10.1182/blood.V124.21.3533.3533
Published: 2014
Journal Articles

The O-Linked N-Acetylglucosamine Transferase Modifies HOXA9 and Inhibits HOXA9-Driven Immortalization

Jean-Francois M Rual, PhD, Jay L. Hess, MD, PhD, MHSA, Tao Xu, PhD, Cailin Collins, Honglai Zhang, PhD, Kimberly Ha, Sung Soo Park, PhD, Joel Bronstein, Jingya Wang
Journal: Blood
Blood (2013) 122 (21): 4901.
https://doi.org/10.1182/blood.V122.21.4901.4901
Published: 2013
Journal Articles

Mechanisms of Transcriptional Regulation and Transformation by HOXA9

Jay L. Hess, MD, PhD, Cailin Collins, Joel Bronstein, Yuqing Sun, Surya Nagaraja
Journal: Blood
Blood (2012) 120 (21): SCI-30.
https://doi.org/10.1182/blood.V120.21.SCI-30.SCI-30
Published: 2012
Journal Articles

C/ebpα and Pu.1 Are Members of a Critical Regulatory Network Required for Hoxa9-Mediated Immortalization

Cailin Collins, Jingya Wang, Joel Bronstein, Jay L. Hess, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 650.
https://doi.org/10.1182/blood.V120.21.650.650
Published: 2012
Journal Articles

MLL Fusion Protein Driven AML Is Selectively Inhibited by Targeted Disruption of the MLL-PAFc Interaction

Andrew G. Muntean, PhD, Eric M Granowicz, Jay L. Hess, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 56.
https://doi.org/10.1182/blood.V118.21.56.56
Published: 2011
Journal Articles

MLL-ENL Inhibits Polycomb Repressive Complex 1 to Achieve Efficient Transformation of Hematopoietic Cells

Emanuel Maethner, Constanze Breitinger, Maria-Paz Garcia-Cuellar, Ph.D., Jay L. Hess, MD, PhD, Robert K. Slany, PhD
Journal: Blood
Blood (2011) 118 (21): 2443.
https://doi.org/10.1182/blood.V118.21.2443.2443
Published: 2011
Journal Articles

Targeting Menin-MLL Interaction to Inhibit MLL Fusion Oncoproteins in Leukemia

Jolanta Grembecka, PhD, Shihan He, PhD, Aibin Shi, PhD, Trupta Purohit, Andrew G. Muntean, PhD, Xiaoqin Li, Thomas Hartley, Duxin Sun, PhD, Jay L. Hess, MD, PhD, Tomasz Cierpicki, PhD
Journal: Blood
Blood (2011) 118 (21): 2497.
https://doi.org/10.1182/blood.V118.21.2497.2497
Published: 2011
Journal Articles

A Novel Ubiquitination Pathway Regulates MLL Activity During Hematopoietic Differentiation

Jingya Wang, Ph.D., Andrew G. Muntean, PhD, Jay L. Hess, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 743.
https://doi.org/10.1182/blood.V116.21.743.743
Published: 2010
Journal Articles

Assessment of DOT1L as a Therapeutic Target In Acute Leukemia

Stephanie Y Jo, Eric M Granowicz, Jay L. Hess, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 3291.
https://doi.org/10.1182/blood.V116.21.3291.3291
Published: 2010
Journal Articles

CBX8, a Polycomb-Group Protein, Is Essential for MLL-AF9-Induced Leukemogenesis

Jiaying Tan, Jay L. Hess, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 4174.
https://doi.org/10.1182/blood.V116.21.4174.4174
Published: 2010
Journal Articles

Identification of Hoxa9 Targets in Myeloid Progenitors Using Conditional Expression.

Kajal V. Sitwala, MD, PhD, James W. MacDonald, MS, Diane M. Giannola, MS, Jay L. Hess, MD, PhD
Journal: Blood
Blood (2007) 110 (11): 1230.
https://doi.org/10.1182/blood.V110.11.1230.1230
Published: 2007
Journal Articles

The MLL PHD Fingers of MLL Block MLL Fusion Protein Mediated Transformation.

Andrew G. Muntean, PhD, Jay L. Hess, MD, PhD
Journal: Blood
Blood (2007) 110 (11): 976.
https://doi.org/10.1182/blood.V110.11.976.976
Published: 2007
Journal Articles

MLL Modulates Telomere Length in Mammalian Cells.

Corrado Caslini, PhD, Jay L. Hess, MD/PhD
Journal: Blood
Blood (2006) 108 (11): 2209.
https://doi.org/10.1182/blood.V108.11.2209.2209
Published: 2006
Journal Articles

Interaction of MLL Amino Terminal Sequences with Menin Is Required for Transformation.

Jay L. Hess, MD, PhD, Zhaohai Yang, MD, PhD, Haoren Wang, Ya-Xiong Chen, PhD, Thomas A. Milne, PhD, Mary Ellen Martin, MD, Robert K. Slany, PhD, Xianxin Hua, MD, PhD
Journal: Blood
Blood (2005) 106 (11): 664.
https://doi.org/10.1182/blood.V106.11.664.664
Published: 2005
Journal Articles

c-Myb Is an Essential Downstream Target for Homeobox Mediated Transformation of Hematopoietic Cells.

Robert K. Slany, PhD, Claudia B. Bittner, Deniz T. Zeisig, Christian Bach, Jay L. Hess, MD, PhD
Journal: Blood
Blood (2005) 106 (11): 666.
https://doi.org/10.1182/blood.V106.11.666.666
Published: 2005
Journal Articles

MLL-AF9 and MLL-ENL Induce Deregulation of Similar Downstream Candidate Genes: An Analysis across Experimental Protocols and Laboratories.

Ashish R. Kumar, MD, PhD, Robert K. Slany, PhD, Jay L. Hess, MD, PhD, John H. Kersey, MD
Journal: Blood
Blood (2004) 104 (11): 3372.
https://doi.org/10.1182/blood.V104.11.3372.3372
Published: 2004