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Journal Articles

Using the Zebrafish to Model the Tumour-Suppressor Effects of NUP98 in NUP98-NSD1 mediated AML

Corey Filiaggi, BScH, Vinothkumar Rajan, B.Tech, Sergey Prykhozhij, PhD, Adam P Deveau, BScH, MSc, Jason N. Berman, MD

Blood (2016) 128 (22): 5117.

https://doi.org/10.1182/blood.V128.22.5117.5117

Published: 2016

Journal Articles

Phloridzin Docosahexaenoate (PZ-DHA) : A Novel Naturally Derived Drug Active in T-Cell Acute Lymphoblastic Leukemia (T-ALL)

Niroshaathevi Arumuggam, BSc, Nicole Melong, MSc, Catherine K.L. Too, PhD, Jason N. Berman, MD, H.P. Vasantha Rupasinghe, PhD

Blood (2016) 128 (22): 5197.

https://doi.org/10.1182/blood.V128.22.5197.5197

Published: 2016

Journal Articles

The Novel Sulfonamidebenzamide ML291 Activates Apoptotic UPR Signaling in Pediatric Leukemia

Danielle Garshott, Nicole Melong, MSc, Tania T. Sarker, MD MPH, Yue Xi, PhD, Amy Brownell, Michael Callaghan, MD, Jason N. Berman, MD, Andrew Fribley, PhD

Blood (2016) 128 (22): 3523.

https://doi.org/10.1182/blood.V128.22.3523.3523

Published: 2016

Journal Articles

Down Syndrome AML Is Unique in Phenotype Both at Diagnosis and in Post Chemotherapy Regeneration

Elisabeth R Wilson, Lisa Eidenschink Brodersen, PhD, Barbara Katharina Zehentner, PhD, Andrew J. Menssen, Andrew P. Voigt, Laura Pardo, Denise A. Wells, MD, Johann Hitzler, MD FRCP (C), FAAP, Jason N. Berman, MD, Todd A. Alonzo, PhD, Samir B. Kahwash, Soheil Meshinchi, MD PhD, Michael R. Loken, PhD

Blood (2016) 128 (22): 1687.

https://doi.org/10.1182/blood.V128.22.1687.1687

Published: 2016

Journal Articles

Bone Marrow Failure and Developmental Delay Caused By Mutations in Poly(A)-Specific Ribonuclease

Blood (2015) 126 (23): 2404.

https://doi.org/10.1182/blood.V126.23.2404.2404

Published: 2015

Journal Articles

Fishing with a Transgenic Line: Using Zebrafish to Elucidate Mechanisms and Therapeutics in NUP98-NSD1 AML

Corey Filiaggi, BScH, Adam P Deveau, BScH, MSc, Sergey Prykhozhij, PhD, Graham Dellaire, PhD, Jason N. Berman, MD

Blood (2015) 126 (23): 1638.

https://doi.org/10.1182/blood.V126.23.1638.1638

Published: 2015

Journal Articles

A Humanized Zebrafish Transplant Model Expressing CXCL12 Provides an Enhanced In Vivo Therapeutic Screening Platform for T-ALL

Vinothkumar Rajan, B.Tech, Nicole Melong, M.Sc, Clinton JV Campbell, PhD MD, Graham Dellaire, PhD, Jason N. Berman, MD

Blood (2015) 126 (23): 4273.

https://doi.org/10.1182/blood.V126.23.4273.4273

Published: 2015

Journal Articles

The Zebrafish Provides Mechanistic Insights into the Role of Poly(A)-Specific Ribonuclease ( PARN ) in Hematopoietic Stem Cell (HSC) Homeostasis and Bone Marrow Failure

Adam P Deveau, BScH, MSc, Andrew J Coombs, BScH, Santhosh Dhanraj, BSc, MSc, Gretchen Wagner, BScH, Yigal Dror, MD FRCP(C), Jason N. Berman, MD

Blood (2015) 126 (23): 668.

https://doi.org/10.1182/blood.V126.23.668.668

Published: 2015

Journal Articles

Characterizing Transcriptional and Epigenetic Signatures Induced By FLT3-ITD Activation

Barbara Spitzer, MD, Olga A Guryanova, MD PhD, Omar Abdel-Wahab, MD, Nicole Kucine, MD, Mazhar Adli, PhD, Jason N. Berman, MD, Soheil Meshinchi, MD PhD, Bradley Bernstein, MD PhD, Raphael Pelossof, PhD, Christina Leslie, PhD, Ross L. Levine, MD

Blood (2014) 124 (21): 2186.

https://doi.org/10.1182/blood.V124.21.2186.2186

Published: 2014

Journal Articles

Preclinical Determination of the Efficacy of Epigenetic Therapy in High Risk Myeloid Disease Using the Zebrafish Model

Adam Deveau, BSc, MSc, Alexander Michael Forrester, BSc, PhD, Andrew J Coombs, BScH, Gretchen S Wagner, BScH, Clemens Grabher, PhD, Ian Chute, MSc, Daniel Leger, MSc, Stephen Lewis, PhD, Matthew Mingay, BSc, Martin Hirst, PhD, A. Thomas Look, MD, Jason N. Berman, MD

Blood (2014) 124 (21): 436.

https://doi.org/10.1182/blood.V124.21.436.436

Published: 2014

Journal Articles

Improvement in Treatment Outcome and Identification of a New Prognostic Parameter in Down Syndrome Acute Myeloid Leukemia (DS-AML): Results of the Children’s Oncology Group (COG) Phase III AAML0431 Trial

Jeffrey W Taub, MD, Jason N Berman, MD, Johann K. Hitzler, MD, April D. Sorrell, MD, Norman J. Lacayo, MD, Kelley Mast, MD, David R. Head, MD, Susana C. Raimondi, PhD, Betsy A. Hirsch, PhD, Robert B. Gerbing, MA, Todd A. Alonzo, PhD, Dario Campana, MD PhD, Elaine Coustan-Smith, MS, Prasad Mathew, Alan S. Gamis, MD MPH

Blood (2014) 124 (21): 278.

https://doi.org/10.1182/blood.V124.21.278.278

Published: 2014

Journal Articles

Zebrafish Xenotransplantation and Focused Chemical Genomics: A Preclinical Therapeutic Model For T-Cell Acute Lymphoblastic Leukemia

Victoria L Bentley, BSc, Chansey J Veinotte, MSc, Dale Corkery, BSc., Marissa A Leblanc, PhD, Karen Bedard, PhD, Andrew P Weng, MD, PhD, Graham Dellaire, PhD., Jason N Berman, MD

Blood (2013) 122 (21): 2670.

https://doi.org/10.1182/blood.V122.21.2670.2670

Published: 2013

Journal Articles

Glycine Supplementation – A Novel Therapeutic Strategy for Congenital Sideroblastic Anemia.

Jason N Berman, MD, Pedro Fernandez-Murray, PhD, Gheyath Nasrallah, PhD, Noelia Dufay, PhD, Conrad V Fernandez, FRCPC, BSc, MD, Ameer Jarrar, MSc, Andrew J Coombs, BSc(Hon), Christopher McMaster, PhD

Blood (2012) 120 (21): 2087.

https://doi.org/10.1182/blood.V120.21.2087.2087

Published: 2012

Journal Articles

Epigenetic Therapy Inhibits NUP98-HOXA9 -Mediated Myeloid Disease – Decitabine and Valproic Acid Work Synergistically to Rescue Normal Hematopoiesis in Transgenic Zebrafish.

Adam Deveau, BSc(Hons), A. Michael Forrester, PhD, Clemens Grabher, Andrew J Coombs, BSc(Hon), Ian Chute, MSc, Daniel Leger, MSc, Stephen Lewis, PhD, A. Thomas Look, M.D., Jason N Berman, MD

Blood (2012) 120 (21): 2391.

https://doi.org/10.1182/blood.V120.21.2391.2391

Published: 2012

Journal Articles

Using the Zebrafish As a Tool for Modeling Systemic Mastocytosis,

Tugce B Balci, MD, Andrew J Coombs, BSc(Hon), Chloe Grondin, Sahar I Da'as, MSc, Ian Chute, MSc, Daniel Leger, MSc, Adolfo A. Ferrando, MD, PhD, Stephen Lewis, PhD, Jason N Berman, MD

Blood (2011) 118 (21): 3208.

https://doi.org/10.1182/blood.V118.21.3208.3208

Published: 2011

Journal Articles

NUP98-HOXA9 drives High-Risk Myeloid Disease in Zebrafish – An In Vivo platform to Study Interacting Genes and Perform Drug Discovery,

A. Michael Forrester, BSc(Hon), Andrew J Coombs, BSc(Hon), Eileen R McBride, MD, FRCP(C), Ian Chute, MSc, Daniel Leger, MSc, Stephen Lewis, PhD, Clemens Grabher, PhD, Thomas Look, MD, Jason N Berman, MD

Blood (2011) 118 (21): 3622.

https://doi.org/10.1182/blood.V118.21.3622.3622

Published: 2011

Journal Articles

Human Leukemia Xenotransplantation Into Zebrafish Embryos as An In Vivo Assay for Chemotherapy Drug Response

Dale Corkery, BSc., Graham Dellaire, PhD., Jason N Berman, MD

Blood (2010) 116 (21): 1704.

https://doi.org/10.1182/blood.V116.21.1704.1704

Published: 2010

Journal Articles

The Incidence and Prognostic Significance of 9p21 Abnormalities In Pediatric Acute Lymphoblastic Leukemia Patients – the IWK Experience

Brett Gardiner, BSc, Barbara Morash, PhD, FCCMG, Christie Riddell, PhD, Hao Wang, Conrad V Fernandez, FRCPC, BSc, MD, Margaret Yhap, MD, Jason N Berman, MD

Blood (2010) 116 (21): 1705.

https://doi.org/10.1182/blood.V116.21.1705.1705

Published: 2010

Journal Articles

Do the SLC25A38 or ALAS2 Genes Play a Role In the Phenotypic Expression of Ringed Sideroblasts In Acquired Myelodysplastic Syndrome?

Conrad V Fernandez, MD, Stephen Couban, BSc, MD, Robert Liwski, MD, Makota P Matsuoka, PhD, Barbara Morash, PhD, FCCMG, Jason N Berman, MD, Wenda Greer, PhD, FCCMG, Andrew C Orr, MD, Duane L Guernsey, PhD

Blood (2010) 116 (21): 4954.

https://doi.org/10.1182/blood.V116.21.4954.4954

Published: 2010

Journal Articles

Significant Discrepancy In Peripheral Blood Compared to Bone Marrow BCR-ABL Transcript Levels In Chronic Phase Chronic Myeloid Leukemia (CML)

Jason N Berman, MD, Wenda Greer, PhD, FCCMG, Ridas Juskevicius, MD, Conrad V Fernandez, FRCPC, BSc, MD, Mark Bernstein, MD, Stephen Couban, BSc, MD

Blood (2010) 116 (21): 4471.

https://doi.org/10.1182/blood.V116.21.4471.4471

Published: 2010

NARROW

Using the Zebrafish to Model the Tumour-Suppressor Effects of NUP98 in NUP98-NSD1 mediated AML

Phloridzin Docosahexaenoate (PZ-DHA) : A Novel Naturally Derived Drug Active in T-Cell Acute Lymphoblastic Leukemia (T-ALL)

The Novel Sulfonamidebenzamide ML291 Activates Apoptotic UPR Signaling in Pediatric Leukemia

Down Syndrome AML Is Unique in Phenotype Both at Diagnosis and in Post Chemotherapy Regeneration

Bone Marrow Failure and Developmental Delay Caused By Mutations in Poly(A)-Specific Ribonuclease

Fishing with a Transgenic Line: Using Zebrafish to Elucidate Mechanisms and Therapeutics in NUP98-NSD1 AML

A Humanized Zebrafish Transplant Model Expressing CXCL12 Provides an Enhanced In Vivo Therapeutic Screening Platform for T-ALL

The Zebrafish Provides Mechanistic Insights into the Role of Poly(A)-Specific Ribonuclease ( PARN ) in Hematopoietic Stem Cell (HSC) Homeostasis and Bone Marrow Failure

Characterizing Transcriptional and Epigenetic Signatures Induced By FLT3-ITD Activation

Preclinical Determination of the Efficacy of Epigenetic Therapy in High Risk Myeloid Disease Using the Zebrafish Model

Improvement in Treatment Outcome and Identification of a New Prognostic Parameter in Down Syndrome Acute Myeloid Leukemia (DS-AML): Results of the Children’s Oncology Group (COG) Phase III AAML0431 Trial

Zebrafish Xenotransplantation and Focused Chemical Genomics: A Preclinical Therapeutic Model For T-Cell Acute Lymphoblastic Leukemia

Glycine Supplementation – A Novel Therapeutic Strategy for Congenital Sideroblastic Anemia.

Epigenetic Therapy Inhibits NUP98-HOXA9 -Mediated Myeloid Disease – Decitabine and Valproic Acid Work Synergistically to Rescue Normal Hematopoiesis in Transgenic Zebrafish.

Using the Zebrafish As a Tool for Modeling Systemic Mastocytosis,

NUP98-HOXA9 drives High-Risk Myeloid Disease in Zebrafish – An In Vivo platform to Study Interacting Genes and Perform Drug Discovery,

Human Leukemia Xenotransplantation Into Zebrafish Embryos as An In Vivo Assay for Chemotherapy Drug Response

The Incidence and Prognostic Significance of 9p21 Abnormalities In Pediatric Acute Lymphoblastic Leukemia Patients – the IWK Experience

Do the SLC25A38 or ALAS2 Genes Play a Role In the Phenotypic Expression of Ringed Sideroblasts In Acquired Myelodysplastic Syndrome?

Significant Discrepancy In Peripheral Blood Compared to Bone Marrow BCR-ABL Transcript Levels In Chronic Phase Chronic Myeloid Leukemia (CML)

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American Society of Hematology

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American Society of Hematology

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