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Journal Articles

Genotype-Phenotype Correlations in Patients with Myeloid Malignancies Using Explainable Artificial Intelligence

Nathan Radakovich, BA, Luca Malcovati, MD, Manja Meggendorfer, PhD, Mikkael A. Sekeres, MD MS, Jacob Shreve, MD MS, Cameron Beau Hilton, MD, Yazan Rouphail, Wencke Walter, PhD, Stephan Hutter, PhD, Anna Gallì, Sarah Pozzi, Aaron T. Gerds, MDMS, Sudipto Mukherjee, MD PhD MPH, Cassandra M Kerr, MS, Babal K. Jha, PhD, Claudia Haferlach, MD, Jaroslaw P. Maciejewski, MD PhD, Torsten Haferlach, MD, Aziz Nazha, MD

Blood (2020) 136 (Supplement 1): 31–32.

https://doi.org/10.1182/blood-2020-140023

Published: 2020

Journal Articles

Personalized Transcriptomic Analyses Identify Unique Signatures That Correlate with Genomic Subtypes in Acute Myeloid Leukemia (AML) Using Explainable Artificial Intelligence

Yazan Rouphail, Nathan Radakovich, BA, Jacob Shreve, MD MS, Sudipto Mukherjee, MD PhD MPH, Babal K. Jha, PhD, Jaroslaw P. Maciejewski, MD PhD, Mikkael A. Sekeres, MD MS, Aziz Nazha, MD

Blood (2020) 136 (Supplement 1): 33–34.

https://doi.org/10.1182/blood-2020-139522

Published: 2020

Journal Articles

Aberrant Telomere Length and Composition Are Recurrent Features of Myeloid Disorders

Adam Wahida, Stephan Hutter, PhD, Manja Meggendorfer, PhD, Claudia Haferlach, MD, Wolfgang Kern, MD, Jaroslaw P. Maciejewski, MD PhD, Torsten Haferlach, MD

Blood (2020) 136 (Supplement 1): 29–30.

https://doi.org/10.1182/blood-2020-140662

Published: 2020

Journal Articles

Immunogenomics of Aplastic Anemia: The Role of HLA Somatic Mutations and the HLA Evolutionary Divergence

Simona Pagliuca, MD, Carmelo Gurnari, MD, Hassan Awada, MD, Cassandra M Kerr, MS, Bhumika J. Patel, MD, Laila Terkawi, Misam Zawit, MBBS, Sunisa Kongkiatkamon, MD, Pedro H Prata, MD, Ashwin Kishtagari, MBBS, Adam Wahida, Thomas Laframboise, PhD, Valeria Visconte, PhD, Regis Peffault De Latour, MD PhD, Jaroslaw P. Maciejewski, MD PhD

Blood (2020) 136 (Supplement 1): 20–21.

https://doi.org/10.1182/blood-2020-142501

Published: 2020

Journal Articles

Immunogenomics of Paroxysmal Nocturnal Hemoglobinuria: A Model of Immune Escape

Carmelo Gurnari, MD, Simona Pagliuca, MD, Cassandra M Kerr, MS, Hassan Awada, MD, Sunisa Kongkiatkamon, MD, Laila Terkawi, Neetha Parameswaran, PhD, Misam Zawit, MBBS, Adam Wahida, Valeria Visconte, PhD, Jaroslaw P. Maciejewski, MD PhD

Blood (2020) 136 (Supplement 1): 21–22.

https://doi.org/10.1182/blood-2020-140030

Published: 2020

Journal Articles

Molecular and Expression Characterization of Monosomy 7 and Del(7q)

Vera Adema, PhD, Cassandra M Kerr, MS, Hassan Awada, MD, Sunisa Kongkiatkamon, MD, Bhumika J. Patel, MD, Mikkael A. Sekeres, MD MS, Valeria Visconte, PhD, John Barnard, Jaroslaw P. Maciejewski, MD PhD, Torsten Haferlach, MD

Blood (2020) 136 (Supplement 1): 33.

https://doi.org/10.1182/blood-2020-142507

Published: 2020

Journal Articles

Double Genetic Hits and Subclonal Mosaicism in the Ras Signaling Pathway in Myeloid Neoplasia

Sunisa Kongkiatkamon, MD, Yasunobu Nagata, MD PhD, Vera Adema, PhD, Hassan Awada, MD, Misam Zawit, MD, Laila Terkawi, Simona Pagliuca, MD, Carmelo Gurnari, MD, Cassandra M Kerr, MS, Mikkael A. Sekeres, MD MS, Hetty E. Carraway, MD MBA, Yogenthiran Saunthararajah, MD, Bhumika J. Patel, MD, Jaroslaw P. Maciejewski, MD PhD, Valeria Visconte, PhD

Blood (2020) 136 (Supplement 1): 34–35.

https://doi.org/10.1182/blood-2020-143210

Published: 2020

Journal Articles

Leveraging Whole Genome Sequencing to Define the Mutational Landscape in Paroxysmal Nocturnal Hemoglobinuria

Adam Wahida, Stephan Hutter, PhD, Manja Meggendorfer, PhD, Cassandra M. Kerr, MS, Carmelo Gurnari, MD, Elisabeth Weiss, PhD, Claudia Haferlach, MD, Wolfgang Kern, MD, Jaroslaw P. Maciejewski, MD PhD, Torsten Haferlach, MD

Blood (2020) 136 (Supplement 1): 8.

https://doi.org/10.1182/blood-2020-139335

Published: 2020

Journal Articles

The Genomic Landscape of Wilms' Tumor 1 ( WT1 ) Mutant Acute Myeloid Leukemia

Hassan Awada, MD, Arda Durmaz, Carmelo Gurnari, MD, Misam Zawit, MBBS, Sunisa Kongkiatkamon, MD, Simona Pagliuca, MD, Cassandra M. Kerr, MS, Hetty E. Carraway, MD MBA, Aziz Nazha, MD, Mikkael A. Sekeres, MD MS, Jaroslaw P. Maciejewski, MD PhD, Valeria Visconte, PhD

Blood (2020) 136 (Supplement 1): 28.

https://doi.org/10.1182/blood-2020-139920

Published: 2020

Journal Articles

Venetoclax Inhibition of Pyrimidine Synthesis Guides Methods for Integration with Decitabine or 5-Azacytidine That Are Non-Myelosuppressive

Xiaorong Gu, PhD, Rita Tohme, PhD, Mendel Goldfinger, MD, Benjamin K. Tomlinson, MD, Nneha Sakre, PhD, Shannon Hanmer, Babal K. Jha, PhD, Jaroslaw P. Maciejewski, MD PhD, Amit Verma, MBBS, Yogenthiran Saunthararajah, MD

Blood (2020) 136 (Supplement 1): 26–27.

https://doi.org/10.1182/blood-2020-143200

Published: 2020

Journal Articles

Inhibition of Critical DNA Dioxygenase Activity in IDH1/2 Mutant Myeloid Neoplasms

Simona Pagliuca, MD, Yihong Guan, PhD, Anand D. Tiwari, PhD, Dale Grabowski, BS, Carmelo Gurnari, MD, Cassandra M Kerr, MS, Sunisa Kongkiatkamon, MD, Metis Hasipek, PhD, Laila Terkawi, Misam Zawit, MBBS, Hassan Awada, MD, Valeria Visconte, PhD, Yogenthiran Saunthararajah, MD, James G Phillips, PhD, Jaroslaw P. Maciejewski, MD PhD, Babal K. Jha, PhD

Blood (2020) 136 (Supplement 1): 28.

https://doi.org/10.1182/blood-2020-143094

Published: 2020

Journal Articles

A Personalized Clinical-Decision Tool to Improve the Diagnostic Accuracy of Myelodysplastic Syndromes

Blood (2020) 136 (Supplement 1): 33–35.

https://doi.org/10.1182/blood-2020-139412

Published: 2020

Journal Articles

Targeted Sequencing of 7 Genes Can Help Reduce Pathologic Misclassification of MDS

Blood (2020) 136 (Supplement 1): 32–33.

https://doi.org/10.1182/blood-2020-140317

Published: 2020

Journal Articles

Multicenter Validation of a Personalized Model to Predict Hypomethylating Agent Response in Myelodysplastic Syndromes (MDS)

Nathan Radakovich, BA, David A. Sallman, MD, Rena J. Buckstein, MD FRCPC, Andrew M. Brunner, MD, Sudipto Mukherjee, MD PhD MPH, Rami Komrokji, MD, Najla Al Ali, M.Sc, Jacob Shreve, MD MS, Yazan Rouphail, Cassandra M Kerr, MS, Yihong Guan, PhD, Teodora Kuzmanovic, BA, Metis Hasipek, PhD, Babal K. Jha, PhD, Jaroslaw P. Maciejewski, MD PhD, Mikkael A. Sekeres, MD MS, Aziz Nazha, MD

Blood (2020) 136 (Supplement 1): 54–55.

https://doi.org/10.1182/blood-2020-139815

Published: 2020

Journal Articles

A Phase I/II Trial of CPX-351 + Palbociclib in Patients with Acute Myeloid Leukemia

Aziz Nazha, MD, Sudipto Mukherjee, MD PhD MPH, Caitlin Siebenaller, PharmD, Madeline Waldron, PharmD, BCOP, Eric Parsons, RN, Jenna Thomas, Hetty E. Carraway, MD MBA, Dale Grabowski, BS, Yihong Guan, PhD, Aaron T. Gerds, MDMS, Bhumika J. Patel, MD, Anjali S Advani, MD, Jaroslaw P. Maciejewski, MD PhD, Mikkael A. Sekeres, MD MS

Blood (2020) 136 (Supplement 1): 13–14.

https://doi.org/10.1182/blood-2020-139494

Published: 2020

Journal Articles

Genotype-Phenotype Relationships and Therapeutic Targets in Acute Erythroid Leukemia

June Takeda, MD, Kenichi Yoshida, MDPhD, Akinori Yoda, PhD, Lee-Yung Shih, MD, Yasuhito Nannya, MD PhD, Yotaro Ochi, MD, Ayana Kon, MD PhD, Kenichi Chiba, Yuichi Shiraishi, PhD, Yusuke Shiozawa, MD PhD, Tetsuichi Yoshizato, MD PhD, Cassandra M Kerr, MS, Yasunobu Nagata, MD PhD, Toshiyuki Kitano, MD PhD, Akira Hangaishi, MD PhD, Ken Ishiyama, MD PhD, Hisashi Tsurumi, MD PhD, Yasushi Miyazaki, MD PhD, Nobuhiro Hiramoto, MD, Takayuki Ishikawa, MD PhD, Masahiro Marshall Nakagawa, MDPhD, Akifumi Takaori-Kondo, MD PhD, Shigeru Chiba, MD PhD, Hideyuki Nakazawa, MD PhD, Ming-Chung Kuo, MD, Keisuke Kataoka, MD PhD, Ryunosuke Saiki, MD, Hiroko Tanaka, Kensuke Usuki, MD PhD, Shuichi Miyawaki, MD PhD, Satoru Miyano, PhD, Jaroslaw P. Maciejewski, MD PhD, Arnold Ganser, Michael Heuser, Prof., MD, Felicitas Thol, Hideki Makishima, MD PhD, Seishi Ogawa, MD PhD

Blood (2020) 136 (Supplement 1): 17–18.

https://doi.org/10.1182/blood-2020-141750

Published: 2020

Journal Articles

Molecular and Clinical Aspects of Acute Myeloid Leukemia with Inv(3)(q21q26)/t(3;3)(q21;q26) Carrying Spliceosomal Mutations

Hassan Awada, MD, Cassandra M Kerr, MS, Heesun J. Rogers, MD PhD, Jaroslaw P. Maciejewski, MD PhD, Valeria Visconte, PhD

Blood (2020) 136 (Supplement 1): 7–8.

https://doi.org/10.1182/blood-2020-139953

Published: 2020

Journal Articles

Genomic Landscape of Splicing Factor Mutant Acute Myeloid Leukemia

Hassan Awada, MD, Arda Durmaz, Cassandra M. Kerr, MS, Jaroslaw P. Maciejewski, MD PhD, Valeria Visconte, PhD

Blood (2020) 136 (Supplement 1): 36.

https://doi.org/10.1182/blood-2020-139470

Published: 2020

Journal Articles

TET2 Inhibitory Effects of Eltrombopag Contribute Its Hematopoietic Activity

Yihong Guan, PhD, Metis Hasipek, PhD, Bhumika J. Patel, MD, Dale Grabowski, BS, Anand D. Tiwari, PhD, Sunisa Kongkiatkamon, MD, Cassandra M Kerr, MS, Aziz Nazha, MD, Yogenthiran Saunthararajah, MD, Mikkael A. Sekeres, MD MS, Jaroslaw P. Maciejewski, MD PhD, Babal K. Jha, PhD

Blood (2020) 136 (Supplement 1): 2–3.

https://doi.org/10.1182/blood-2020-142875

Published: 2020

Journal Articles

Impact of Pathogenic Germ Line Variants in Adults with Acquired Bone Marrow Failure Syndromes Vs . Myeloid Neoplasia

Misam Zawit, MBBS, Jibran Durrani, MD, Wenyi Shen, MD, Vera Adema, PhD, Cassandra M Kerr, MS, Hassan Awada, MD, Sunisa Kongkiatkamon, MD, Carmelo Gurnari, MD, Simona Pagliuca, MD, Laila Terkawi, Bhumika J. Patel, MD, Valeria Visconte, PhD, Hetty E. Carraway, MD MBA, Thomas LaFramboise, PhD, Seth J. Corey, MD, Torsten Haferlach, MD, Jaroslaw P. Maciejewski, MD PhD

Blood (2020) 136 (Supplement 1): 1.

https://doi.org/10.1182/blood-2020-142586

Published: 2020

NARROW

Genotype-Phenotype Correlations in Patients with Myeloid Malignancies Using Explainable Artificial Intelligence

Personalized Transcriptomic Analyses Identify Unique Signatures That Correlate with Genomic Subtypes in Acute Myeloid Leukemia (AML) Using Explainable Artificial Intelligence

Aberrant Telomere Length and Composition Are Recurrent Features of Myeloid Disorders

Immunogenomics of Aplastic Anemia: The Role of HLA Somatic Mutations and the HLA Evolutionary Divergence

Immunogenomics of Paroxysmal Nocturnal Hemoglobinuria: A Model of Immune Escape

Molecular and Expression Characterization of Monosomy 7 and Del(7q)

Double Genetic Hits and Subclonal Mosaicism in the Ras Signaling Pathway in Myeloid Neoplasia

Leveraging Whole Genome Sequencing to Define the Mutational Landscape in Paroxysmal Nocturnal Hemoglobinuria

The Genomic Landscape of Wilms' Tumor 1 ( WT1 ) Mutant Acute Myeloid Leukemia

Venetoclax Inhibition of Pyrimidine Synthesis Guides Methods for Integration with Decitabine or 5-Azacytidine That Are Non-Myelosuppressive

Inhibition of Critical DNA Dioxygenase Activity in IDH1/2 Mutant Myeloid Neoplasms

A Personalized Clinical-Decision Tool to Improve the Diagnostic Accuracy of Myelodysplastic Syndromes

Targeted Sequencing of 7 Genes Can Help Reduce Pathologic Misclassification of MDS

Multicenter Validation of a Personalized Model to Predict Hypomethylating Agent Response in Myelodysplastic Syndromes (MDS)

A Phase I/II Trial of CPX-351 + Palbociclib in Patients with Acute Myeloid Leukemia

Genotype-Phenotype Relationships and Therapeutic Targets in Acute Erythroid Leukemia

Molecular and Clinical Aspects of Acute Myeloid Leukemia with Inv(3)(q21q26)/t(3;3)(q21;q26) Carrying Spliceosomal Mutations

Genomic Landscape of Splicing Factor Mutant Acute Myeloid Leukemia

TET2 Inhibitory Effects of Eltrombopag Contribute Its Hematopoietic Activity

Impact of Pathogenic Germ Line Variants in Adults with Acquired Bone Marrow Failure Syndromes Vs . Myeloid Neoplasia

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American Society of Hematology

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American Society of Hematology

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