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James Bradner, M.D.
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Journal Articles

Treatment with Histone Deacetylase 6-Specific Inhibitor WT-161 Disrupts hsp90 Function, Abrogates Aggresome Formation and Sensitizes Human Mantle Cell Lymphoma Cells to Lethal ER Stress Induced by Proteasome Inhibitor Carfilzomib

Rekha Rao, Warren Fiskus, BSc, PhD, Ramesh Balusu, Hongwei Ma, James Bradner, M.D., Jianguo Tao, MD, PhD, Eduardo M. Sotomayor, MD, Kapil N. Bhalla, MD
Journal: Blood
Blood (2010) 116 (21): 2856.
https://doi.org/10.1182/blood.V116.21.2856.2856
Published: 2010
Journal Articles

Selective Inhibition of HDAC1 and HDAC2 Is a Potential Therapeutic Option for B-All

Matthew C. Stubbs, PhD, Won-Il Kim, Ph.D., Tina Davis, Jun Qi, Ph.D., James Bradner, M.D., Andrew L. Kung, MD, PhD, Scott A. Armstrong, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 2900.
https://doi.org/10.1182/blood.V116.21.2900.2900
Published: 2010
Journal Articles

Selective Inhibition of HDAC6 with a New Prototype Inhibitor (ACY-1215) Overcomes Bortezomib Resistance In Multiple Myeloma (MM)

Loredana Santo, MD, Teru Hideshima, MD, PhD, Andrew L. Kung, MD, PhD, Matthew Jarpe, PhD, Diana Cirstea, M.D., Kishan Patel, Samantha Pozzi, MD, Jen C. Tseng, PhD, Scott J Rodig, James Bradner, M.D., Kenneth C. Anderson, MD, Simon Jones, PhD, Noopur Raje, MD
Journal: Blood
Blood (2010) 116 (21): 2997.
https://doi.org/10.1182/blood.V116.21.2997.2997
Published: 2010
Journal Articles

Autophagy as a Target Pathway in Multiple Myeloma: A Forward Chemical Genetic Approach.

John P. Shen, BS, Sanjay Divakaran, Letian Kuai, Ph.D., Xiang Wang, Ph.D., Shao-En Ong, Ph.D., Ravi Amaravadi, M.D., John Wood, Ph.D., Steven Carr, Ph.D., Stuart Schreiber, Ph.D., Stephen Haggarty, Ph.D., James Bradner, M.D.
Journal: Blood
Blood (2007) 110 (11): 2510.
https://doi.org/10.1182/blood.V110.11.2510.2510
Published: 2007
Journal Articles

Direct Inhibition of the Notch Transactivation Complex with Synthetic Constrained Peptides in T-Cell Acute Lymphoblastic Leukemia.

Raymond Moellering, BA, Melanie Cornejo, B.A., Jennifer Rocknik, B.A., Michael Hancock, Ph.D., Christina DelBianco, Ph.D., Stephen Blacklow, M.D., Ph.D., Gary Gilliland, M.D., Ph.D., Gregory Verdine, Ph.D., James Bradner, M.D.
Journal: Blood
Blood (2007) 110 (11): 2819.
https://doi.org/10.1182/blood.V110.11.2819.2819
Published: 2007
Journal Articles

Identification and Characterization of Novel Small-Molecule Inhibitors of the Replication Checkpoint.

James Bradner, M.D., Yong-Son Kim, M.D., Angela Koehler, Ph.D., Masaoki Kawasumi, M.D., Xiaodong Li, Ph.D., Stuart L. Schreiber, Ph.D., Paul Nghiem, M.D., Ph.D.
Journal: Blood
Blood (2004) 104 (11): 763.
https://doi.org/10.1182/blood.V104.11.763.763
Published: 2004
Journal Articles

Fondaparinux in the Treatment of Heparin-Induced Thrombocytopenia.

James Bradner, M.D., Robert K. Hallisey, M.S., R.Ph., David J. Kuter, M.D., D.Phil.
Journal: Blood
Blood (2004) 104 (11): 1775.
https://doi.org/10.1182/blood.V104.11.1775.1775
Published: 2004