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Hiroshi Handa, M.D.
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Journal Articles

Chromosome 16q Located Genes CDH1, CDH13 and ADAMTS18 Are Correlated and Frequently Methylated But Not Associated With DNMTs levels In Human Lymphoma

Lobna A Alkebsi, Ph.D., Hiroshi Handa, M.D. Ph.D., Kenichi Tahara, M.D., Hiroaki Shimizu, M.D., PhD., Takuma Ishizaki, M.D. Ph.D., Kunio Yanagisawa, M.D., Makiko Takizawa, M.D. Ph.D., Akihiko Yokohama, M.D., Hiromi Koiso, M.D. Ph.D., Takeki Mitsui, M.D. Ph.D., Takayuki Saitoh, M.D. Ph.D., Norifumi Tsukamoto, M.D. Ph.D., Yoshihisa Nojima, M.D. Ph.D., Hirokazu Murakami, M.D.Ph.D.
Journal: Blood
Blood (2013) 122 (21): 4289.
https://doi.org/10.1182/blood.V122.21.4289.4289
Published: 2013
Journal Articles

Normal Karyotype-Acute Myeloid Leukemia With The CD4- CD7+ CD15+ CD34+ Immunophenotype Is a Clinically Distinct Entity With a Favorable Outcome

Noriyoshi Iriyama, Norio Asou, Toru Sakura, MD, PhD, Tomoya Maeda, MD, PhD, Hiroshi Handa, M.D. Ph.D., Masatomo Takahashi, MD, PhD, Shigeki Ohtake, MD, PhD, Yoshihiro Hatta, MD, Hisashi Sakamaki, MD, PhD, Sumihisa Honda, PhD, Yasushi Miyazaki, MD, PhD, Shuichi Miyawaki, MD, Masafumi Taniwaki, MD, PhD, Tomohiko Taki, MD, PhD, Shunichiro Yamaguchi, MD, Shinya Satou, Tomoki Naoe, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 2608.
https://doi.org/10.1182/blood.V122.21.2608.2608
Published: 2013
Journal Articles

Biological Features and Plasticity of CD56-Positive Dendritic-Like Cells: relationship to Blastic Plasmacytoid Dendritic Cell Neoplasm

Yohei Osaki, M.D., Akihiko Yokohama, M.D., Akio Saitoh, M.D. Ph.D., Kenichi Tahara, MD, Kunio Yanagisawa, M.D., Yoshiyuki Ogawa, M.D., Takuma Ishizaki, M.D. Ph.D., Takeki Mitsui, M.D. Ph.D., Hiromi Koiso, M.D. Ph.D., Makiko Takizawa, M.D. Ph.D., Hideki Uchiumi, M.D., Hirokazu Murakami, M.D.Ph.D., Takayuki Saitoh, M.D. Ph.D., Norifumi Tsukamoto, MD, PhD, Hiroshi Handa, M.D. Ph.D., Yoshihisa Nojima, M.D. Ph.D.
Journal: Blood
Blood (2012) 120 (21): 1486.
https://doi.org/10.1182/blood.V120.21.1486.1486
Published: 2012
Journal Articles

The Polymorphisms of Base Excision Repair Genes Influence the Prognosis of Multiple Myeloma

Chiaki Ushie, Takayuki Saitoh, M.D. Ph.D., Atsushi Iwasaki, Norihiko Moriyama, Hikaru Hattori, Morio Matsumoto, MD, Morio Sawamura, M.D. Ph.D., Jun Isoda, M.D. Ph.D., Hiroshi Handa, M.D. Ph.D., Akihiko Yokohama, MD, PhD, Norifumi Tsukamoto, MD, PhD, Hatsue Ogawara, Ph.D., Hirokazu Murakami, M.D., Ph.D.
Journal: Blood
Blood (2012) 120 (21): 3981.
https://doi.org/10.1182/blood.V120.21.3981.3981
Published: 2012
Journal Articles

Association Between Micro-RNA and Epigenetic Modifiers DNA Methyltransferases (DNMTs), Histone Deacetylases (HDACs) in Multiple Myeloma (MM) and Monoclonal Gammmopathy with Undetermined Significance (MGUS)

Hiroshi Handa, M.D. Ph.D., Hikaru Hattori, Noriyuki Takahashi, Yoshiko Sasaki, Takayuki Saitoh, M.D. Ph.D., Yohei Osaki, MD, Kenichi Tahara, MD, Hiromi Koiso, M.D. Ph.D., Takeki Mitsui, M.D. Ph.D., Hiroaki Shimizu, M.D., Makiko Takizawa, M.D. Ph.D., Akihiko Yokohama, MD, PhD, Norifumi Tsukamoto, MD, PhD, Lobna Alkebsi, Yoshihisa Nojima, M.D. Ph.D., Hirokazu Murakami, M.D.Ph.D.
Journal: Blood
Blood (2012) 120 (21): 3942.
https://doi.org/10.1182/blood.V120.21.3942.3942
Published: 2012
Journal Articles

Polymorphisms of IL-10, IL-17A, IL-17F and IL-18 Affect the Clinical Features of Multiple Myeloma in Japanese Patients

Atsushi Iwasaki, Takayuki Saitoh, M.D. Ph.D., Chiaki Ushie, Norihiko Moriyama, Tomonori Takani, Hikaru Hattori, Hiroshi Handa, M.D. Ph.D., Morio Matsumoto, MD, Jun Isoda, M.D. Ph.D., Morio Sawamura, M.D. Ph.D., Hatsue Ogawara, Ph.D., Hirokazu Murakami, M.D. Ph.D.
Journal: Blood
Blood (2012) 120 (21): 4972.
https://doi.org/10.1182/blood.V120.21.4972.4972
Published: 2012
Journal Articles

The Cytokine Polymorphisms Affect the Severity of Thrombocytopenia at Diagnosis in Chronic Immune Thrombocytopenia.

Takayuki Saitoh, M.D. Ph.D., Chiaki Ushie, Atsushi Iwasaki, Norihiko Moriyama, Tomonori Takani, Hattori Hikaru, Hiroshi Handa, M.D. Ph.D., Hiromi Koiso, M.D. Ph.D., Akihiko Yokohama, M.D., Norifumi Tsukamoto, MD, PhD, Hatsue Ogawara, Ph.D., Hirokazu Murakami, M.D.Ph.D.
Journal: Blood
Blood (2012) 120 (21): 2194.
https://doi.org/10.1182/blood.V120.21.2194.2194
Published: 2012
Journal Articles

Clinical Significance of Mixed Phenotype in Adult Patients with Philadelphia Chromosome-Positive Acute Leukemia–no Prognostic Impact in the Imatinib Era.

Hiroaki Shimizu, M.D., Akihiko Yokohama, MD, PhD, Hiroko Koya, M.D., Rumi Shimizu, M.D., Nahoko Hatsumi, M.D., Satoru Takada, MD, Takayuki Saitoh, M.D. Ph.D., Toru Sakura, M.D., Shuichi Miyawaki, MD, Hiroshi Handa, M.D. Ph.D.
Journal: Blood
Blood (2012) 120 (21): 2574.
https://doi.org/10.1182/blood.V120.21.2574.2574
Published: 2012
Journal Articles

Common Fragile Site Gene FRA16D WWOX (WW domain containing oxidoreductase) Is Frequently Altered in Plasma Cells of Multiple Myeloma and MGUS, Possibly Related to Disease Development

Yoshiko Sasaki, Hiroshi Handa, M.D. Ph.D., Noriyuki Takahashi, Hikaru Hattori, Takayuki Saitoh, M.D. Ph.D, Yohei Osaki, MD, Morio Matsumoto, MD, Atsushi Isoda, MD, PhD, Morio Sawamura, M.D. Ph.D., Akio Saito, MD, Akihiko Yokohama, M.D. Ph.D., Hiromi Koiso, M.D. Ph.D., Takeki Mitsui, M.D. Ph.D., Norifumi Tsukamoto, M.D. Ph.D., Yoshihisa Nojima, M.D. Ph.D., Hirokazu Murakami, M.D. Ph.D.
Journal: Blood
Blood (2011) 118 (21): 4646.
https://doi.org/10.1182/blood.V118.21.4646.4646
Published: 2011
Journal Articles

Relation of IL-18 Polymorphism to the Susceptibility and Clinical Feature of Multiple Myeloma in Japanese Patients

Takayuki Saitoh, M.D. Ph.D., Norihiko Moriyama, Tomonori Takani, Chiaki Ushie, Takumi Hoshino, M.D., Takeki Mitsui, M.D. Ph.D., Hiromi Koiso, M.D. Ph.D., Akihiko Yokohama, M.D. Ph.D., Hiroshi Handa, M.D. Ph.D., Norifumi Tsukamoto, M.D. Ph.D., Hatsue Ogawara, Ph.D., Morio Sawamura, M.D. Ph.D., Yoshihisa Nojima, M.D. Ph.D., Hirokazu Murakami, M.D. Ph.D.
Journal: Blood
Blood (2011) 118 (21): 5062.
https://doi.org/10.1182/blood.V118.21.5062.5062
Published: 2011
Journal Articles

Association of Interleukin-18 Gene Polymorphism with Severity of Chronic Immune Thrombocytopenia (ITP).

Takayuki Saitoh, M.D., Norihiko Moriyama, Tomonori Takani, Takeki Mitsui, M.D., Takumi Hoshino, M.D., Hiromi Koiso, M.D., Akihiko Yokohama, M.D., Hiroshi Handa, M.D., Masamitsu Karasawa, M.D., Hatsue Ogawara, Ph.D., Norifumi Tsukamoto, M.D., Hirokazu Murakami, M.D.
Journal: Blood
Blood (2010) 116 (21): 3693.
https://doi.org/10.1182/blood.V116.21.3693.3693
Published: 2010
Journal Articles

Interleukin-10 Gene Polymorphism Reflects the Severity of Chronic Idiopathic Thrombocytopenic Purpura.

Takayuki Saitoh, MD, Tetsuhiro Kasamatsu, Madoka Inoue, W.H.S. Al-ma’Quol, Akihiko Yokohama, M.D., Hiroshi Handa, M.D., Takafumi Matsushima, M.D., Norifumi Tsukamoto, M.D., Masamitsu Karasawa, M.D., Hatsue Ogawara, Ph.D., Yoshihisa Nojima, M.D., Hirokazu Murakami, M.D.
Journal: Blood
Blood (2007) 110 (11): 2111.
https://doi.org/10.1182/blood.V110.11.2111.2111
Published: 2007