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Journal Articles

Induction of a Leukemic Bone Marrow Niche Mediated By TGFB1 of Leukemic Blasts in Pediatric Acute Mekaryoblastic Leukemia: Results of an in Vitro and In Vivo Analysis

Theresa Hack, MSc, Stefanie Bertram, MD, Guntram Büsche, MD, Helmut Hanenberg, MD, Ludger Klein-Hitpass, PhD, Nils Von Neuhoff, PhD, Dirk Reinhardt, MD, Markus Schneider, PhD, Mareike Rasche, MD

Blood (2019) 134 (Supplement_1): 3734.

https://doi.org/10.1182/blood-2019-126536

Published: 2019

Journal Articles

Mutational Landscape of Pediatric Acute Myeloid Leukemia: A Report of the AML-BFM Study Group with a Targeted NGS Approach in 525 Patients Integrating De Novo, Relapsed and Secondary AML

Christiane Walter, MSc, Markus Schneider, PhD, Nils Von Neuhoff, PhD, Helmut Hanenberg, MD, Dirk Reinhardt, MD, Mareike Rasche, MD

Blood (2019) 134 (Supplement_1): 1398.

https://doi.org/10.1182/blood-2019-129778

Published: 2019

Journal Articles

NHEJ-Mediated Gene Editing, a Versatile Approach to Correct a Variety of Fanconi Anemia Genes in HSCs

Francisco J Roman-Rodriguez, PhD, Laura Ugalde, Lara A. Alvarez, Begoña Díez-Cabezas, PhD, Jordi Surrallés, PhD, Maria Jose Ramirez, PhD, Massimo Bogliolo, PhD, Helmut Hanenberg, MD PhD, Julian Sevilla, MD PhD, Sandra Rodriguez-Perales, PhD, Raul Torres-Ruiz, PhD, Juan A. Bueren, PhD, Paula Rio, PhD

Blood (2019) 134 (Supplement_1): 4639.

https://doi.org/10.1182/blood-2019-129946

Published: 2019

Journal Articles

P38α/JNK Signaling Restrains Erythropoiesis By Suppressing Ezh2-Mediated Epigenetic Silencing of Bim

Ping Hu, MD PhD, Angel Nebreda, PhD, Helmut Hanenberg, MD, Garrett Kinnebrew, MD, Mircea Ivan, MD PhD, Mervin C. Yoder, MD, Marie-Dominique Filippi, PhD, Hal E. Broxmeyer, PhD, Reuben Kapur, PhD

Blood (2018) 132 (Supplement 1): 3837.

https://doi.org/10.1182/blood-2018-99-117098

Published: 2018

Journal Articles

IL-33/ST2 Triggering of IL-9-Secreting T Cells Alters the Balance of Fatal Immunity and Tumor Immunity

Abdulraouf Ramadan, PhD, Jilu Zhang, PhD, Mohammad Abu Zaid, MD, Heather O'Leary, PhD, Reuben Kapur, PhD, Helmut Hanenberg, MD, Jie Sun, PhD, Hal E. Broxmeyer, PhD, Mark H. Kaplan, PhD, Sophie Paczesny, MD PhD

Blood (2015) 126 (23): 231.

https://doi.org/10.1182/blood.V126.23.231.231

Published: 2015

Journal Articles

Establishing Modified Human CYP4B1 As a Novel Suicide Gene System for Adoptive T-Cell Therapies

Katharina Roellecke, M.Sc., Constanze Wiek, PhD, Christof Kramm, MD, Allan Rettie, PhD, Helmut Hanenberg, MD

Blood (2015) 126 (23): 5550.

https://doi.org/10.1182/blood.V126.23.5550.5550

Published: 2015

Journal Articles

Novel Functional Roles for Ten-Eleven-Translocation 2 (Tet2) in Normal and Leukemic Growth of Mast Cells

Raghuveer Mali, PhD, Holly Rene Martin, PhD, Baskar Ramdas, PhD, Lakshmi Palam, PhD, Valeria Visconte, PhD, Tiu Ramon, MD, Helmut Hanenberg, MD, Mingjiang Xu, MD PhD, Reuben Kapur, PhD

Blood (2015) 126 (23): 775.

https://doi.org/10.1182/blood.V126.23.775.775

Published: 2015

Journal Articles

A Novel Th17-Prone CD146 + CCR5 + T-Cell Population As an Early Marker of Intestinal Graft-Versus-Host Disease

Wei Li, PhD, Liangyi Liu, Aurelie Gomez, MD, Qing Zhang, Jilu Zhang, PhD, Abdulraouf Ramadan, PhD, Christen L Mumaw, BS, Joel K. Greenson, MD, Suntrea Hammer, MD, Jingmei Lin, MD PhD, Thomas M. Braun, PhD, Di Jiang, Elizabeth Virts, PhD, Stephanie L Kelich, Hong Wei Chu, MD PhD, Samir Hanash, MD PhD, Helmut Hanenberg, MD, Sophie Paczesny, MD PhD

Blood (2014) 124 (21): 3.

https://doi.org/10.1182/blood.V124.21.3.3

Published: 2014

Journal Articles

Generation Of FANCA-/- Human CD34+ Hematopoietic Stem Cells By shRNA Knockdown

Zejin Sun, MD, PhD, Rikki Enzor, Paula Rio, PhD, D. Wade Clapp, MD, Helmut Hanenberg, MD

Blood (2013) 122 (21): 2903.

https://doi.org/10.1182/blood.V122.21.2903.2903

Published: 2013

Journal Articles

FANCA Controls Mitotic Phosphosignaling Networks To Ensure Genome Stability During Cell Division

Rikki Enzor, Zahi Abdul Sater, Donna Cerabona, Zejin Sun, MD, PhD, Su-jung Park, PhD, Helmut Hanenberg, MD, D. Wade Clapp, MD, Grzegorz Nalepa, MD, PhD

Blood (2013) 122 (21): 801.

https://doi.org/10.1182/blood.V122.21.801.801

Published: 2013

Journal Articles

Role Of CD166 In Multiple Myeloma Cell Homing To The Bone Marrow Microenvironment and Disease Progression

Linlin Xu, Christophe Machal, Hao Wu, Bradley Poteat, Colin D. Crean, Angelo A. Cardoso, MD, PhD, John M Chirgwin, PhD, Helmut Hanenberg, MD, Khalid S. Mohammad, M.D. Ph.D., Attaya Suvannasankha, MD, Edward F Srour, PhD

Blood (2013) 122 (21): 3102.

https://doi.org/10.1182/blood.V122.21.3102.3102

Published: 2013

Journal Articles

Transduction of Hematopoietic Stem/Progenitor Cells with a Lentivirus Expressing FANCA off the Human Phosphoglycerate Kinase Promoter Corrects the Fanconi Anemia Phenotype,

Zejin Sun, MD, PhD, Jingling Li, Yanzhu Yang, Yan Li, MD, PhD, Dirk Lindemann, Feng-chun Yang, MD, PhD, D. Wade Clapp, MD, Helmut Hanenberg, MD

Blood (2011) 118 (21): 4178.

https://doi.org/10.1182/blood.V118.21.4178.4178

Published: 2011

Journal Articles

A Modified Foamy Viral Envelope Enhances Gene Transfer Efficiency and Reduces Toxicity of Lentiviral FANCA Vectors in Fanca-/- HSCs.

Zejin Sun, MD, PhD, Yan Li, MD, PhD, Jingling Li, MS, Shanbao Cai, MD, PhD, Yi Zeng, MD, PhD, Dirk Lindemann, PhD, Karen E Pollok, PhD, Helmut Hanenberg, MD, PhD, D. Wade Clapp, MD

Blood (2009) 114 (22): 696.

https://doi.org/10.1182/blood.V114.22.696.696

Published: 2009

Journal Articles

Increased TNF/NGF Receptor Expression on BCP-ALL Blasts Carrying the Prognostically Favorable TEL-AML Rearrangement.

Anja Troeger, MD, Ludmila Glouchkova, PhD, Birgit Ackermann, PhD, Gabriele Escherich, MD, Roland Meisel, MD, Hans-Juergen Laws, MD, Helmut Hanenberg, MD, Silja Roettgers, PhD, Gritta Janka-Schaub, MD, Arndt Borkhardt, MD, Ulrich Goebel, MD, Dagmar Dilloo, MD

Blood (2007) 110 (11): 1431.

https://doi.org/10.1182/blood.V110.11.1431.1431

Published: 2007

Journal Articles

High Expression of CD40 on BCP-ALL Blasts Is an Independent Risk Factor Associated with Improved Survival and Enhanced Capacity To Upregulate the Death Receptor CD95.

Anja Troeger, MD, Ludmila Glouchkova, PhD, Birgit Ackermann, PhD, Gabriele Escherich, MD, Roland Meisel, MD, Helmut Hanenberg, MD, Gritta Janka, MD, Ulrich Goebel, MD, Hans-Juergen Laws, MD, Dagmar Dilloo, MD

Blood (2006) 108 (11): 2282.

https://doi.org/10.1182/blood.V108.11.2282.2282

Published: 2006

Journal Articles

In Vivo Selection of Murine Long-Term Repopulating Cells Transduced with a Foamy Virus Vector That Expresses MGMTP140K.

Karen E. Pollok, PhD, Aaron G. Ernstberger, MS, Scott Goebel, MD, PhD, Helmut Hanenberg, MD, PhD, Shanbao Cai, MD, PhD

Blood (2005) 106 (11): 3061.

https://doi.org/10.1182/blood.V106.11.3061.3061

Published: 2005

Journal Articles

Efficient Transduction of Common Marmoset (Callithrix jacchus) Hematopoietic and Embryonic Stem Cells Using Foamyvirus Vectors.

Peter A. Horn, MD, Melanie Wurm, Ryo Kurita, PhD, Tomoko Yokoo, Rainer Blasczyk, MD, Dirk Lindemann, PhD, Helmut Hanenberg, MD, Kenzaburo Tani, MD, PhD

Blood (2005) 106 (11): 5530.

https://doi.org/10.1182/blood.V106.11.5530.5530

Published: 2005

Journal Articles

A Rapid Method for Retroviral Mediated Subtyping of Complementation Group in Fanconi Anemia Patients.

Saurabh Chandra, MBBS, PhD, Orna Levran, PhD, Ingrid Jurickova, MD, Chiel Mass, Rick Kapur, Helmut Hanenberg, MD, Arleen D. Auerbach, PhD, David A. Williams, MD

Blood (2004) 104 (11): 5261.

https://doi.org/10.1182/blood.V104.11.5261.5261

Published: 2004

Journal Articles

High Sensitivity and Specificity of Retroviral Complementation Group Assignment in Primary T Cells of Fanconi Anemia (FA) Patients.

Helmut Hanenberg, MD, Stephan Lobitz, MD, Indira Kokemohr, MD, Silke Furlan, BS, Orna Levran, PhD, Arleen D. Auerbach, PhD, Reinhard Kalb, PhD, Michaela Gross, PhD, Richard Friedl, BS, B. Gottwald, BS, Detlev Schindler, MD

Blood (2004) 104 (11): 3249.

https://doi.org/10.1182/blood.V104.11.3249.3249

Published: 2004

NARROW

Induction of a Leukemic Bone Marrow Niche Mediated By TGFB1 of Leukemic Blasts in Pediatric Acute Mekaryoblastic Leukemia: Results of an in Vitro and In Vivo Analysis

Mutational Landscape of Pediatric Acute Myeloid Leukemia: A Report of the AML-BFM Study Group with a Targeted NGS Approach in 525 Patients Integrating De Novo, Relapsed and Secondary AML

NHEJ-Mediated Gene Editing, a Versatile Approach to Correct a Variety of Fanconi Anemia Genes in HSCs

P38α/JNK Signaling Restrains Erythropoiesis By Suppressing Ezh2-Mediated Epigenetic Silencing of Bim

IL-33/ST2 Triggering of IL-9-Secreting T Cells Alters the Balance of Fatal Immunity and Tumor Immunity

Establishing Modified Human CYP4B1 As a Novel Suicide Gene System for Adoptive T-Cell Therapies

Novel Functional Roles for Ten-Eleven-Translocation 2 (Tet2) in Normal and Leukemic Growth of Mast Cells

A Novel Th17-Prone CD146 + CCR5 + T-Cell Population As an Early Marker of Intestinal Graft-Versus-Host Disease

Generation Of FANCA-/- Human CD34+ Hematopoietic Stem Cells By shRNA Knockdown

FANCA Controls Mitotic Phosphosignaling Networks To Ensure Genome Stability During Cell Division

Role Of CD166 In Multiple Myeloma Cell Homing To The Bone Marrow Microenvironment and Disease Progression

Transduction of Hematopoietic Stem/Progenitor Cells with a Lentivirus Expressing FANCA off the Human Phosphoglycerate Kinase Promoter Corrects the Fanconi Anemia Phenotype,

A Modified Foamy Viral Envelope Enhances Gene Transfer Efficiency and Reduces Toxicity of Lentiviral FANCA Vectors in Fanca-/- HSCs.

Increased TNF/NGF Receptor Expression on BCP-ALL Blasts Carrying the Prognostically Favorable TEL-AML Rearrangement.

High Expression of CD40 on BCP-ALL Blasts Is an Independent Risk Factor Associated with Improved Survival and Enhanced Capacity To Upregulate the Death Receptor CD95.

In Vivo Selection of Murine Long-Term Repopulating Cells Transduced with a Foamy Virus Vector That Expresses MGMTP140K.

Efficient Transduction of Common Marmoset (Callithrix jacchus) Hematopoietic and Embryonic Stem Cells Using Foamyvirus Vectors.

A Rapid Method for Retroviral Mediated Subtyping of Complementation Group in Fanconi Anemia Patients.

High Sensitivity and Specificity of Retroviral Complementation Group Assignment in Primary T Cells of Fanconi Anemia (FA) Patients.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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