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Journal Articles

Bleeding Diathesis in Mice Lacking JAK2 in Platelets

Nathan Eaton, BS, Saravanan Subramaniam, PhD, Marie L Schulte, PhD, Caleb Drew, BS, David Jakab, BS, Sandra L Haberichter, PhD, Hartmut Weiler, PhD, Herve Falet, PhD

Blood (2020) 136 (Supplement 1): 12.

https://doi.org/10.1182/blood-2020-138510

Published: 2020

Journal Articles

Dependence on Schwann Cell-Derived Laminin-γ1 Differentiates Early Lymphoid and Myeloid Development

Kristin Komnick, MPH, Jennifer May, Pouneh Kermani, PhD, Sreemanti Basu, PhD, Irene Hernandez, Mark Zogg, BS, British L Fields, Joshua Morris, MD, Hartmut Weiler, PhD, Karen-Sue Carlson, MDPhD

Blood (2020) 136 (Supplement 1): 37.

https://doi.org/10.1182/blood-2020-142860

Published: 2020

Journal Articles

Atomic-Level Dissection of the Polyclonal Immune Response to the Human Platelet Alloantigen, HPA-1a (Pl A1 )

Huiying Zhi, PhD, Maria Therese Ahlen, PhD, Aye Myat Myat Thinn, PhD, Hartmut Weiler, PhD, Brian R. Curtis, PhD, Bjorn Skogen, MD, Jieqing Zhu, PhD, Peter Newman, PhD

Blood (2018) 132 (Supplement 1): 1258.

https://doi.org/10.1182/blood-2018-99-111327

Published: 2018

Journal Articles

A Murine Model of Type 2N VWD Was Developed By CRISPR/Cas9 Gene Editing and Recapitulates Human Type 2N VWD

Robert R Montgomery, MD, Scot A Fahs, Jeremy G Mattson, Hartmut Weiler, PhD, Qizhen Shi, MD

Blood (2018) 132 (Supplement 1): 221.

https://doi.org/10.1182/blood-2018-99-110324

Published: 2018

Journal Articles

Protein C Activation Is the Critical Thrombomodulin Function in Embryonic and Adult Survival in Mice

Thijs E van Mens, MD MBA, Helena Liang, PhD, Irene Hernandez, MS, Mark Zogg, BS, Jennifer May, Sreemanti Basu, PhD, Berend H. Isermann, MD PhD, Hartmut Weiler, PhD

Blood (2016) 128 (22): 14.

https://doi.org/10.1182/blood.V128.22.14.14

Published: 2016

Journal Articles

Crispr/Cas9-Mediated Generation of Mouse Platelets Expressing the Human Platelet Alloantigen, HPA-1a

Huiying Zhi, MD PhD, Nanyan Zhang, MD PhD, Jamie Foeckler, Shawn Kalloway, PhD, Sridhar Rao, MD PhD, Brian R Curtis, PhD D(ABMLI), Hartmut Weiler, PhD, Peter J. Newman, PhD

Blood (2015) 126 (23): 2341.

https://doi.org/10.1182/blood.V126.23.2341.2341

Published: 2015

Journal Articles

Physiologic Hematopoiesis Is Dependent on Stromal Expression of Laminin-Î³1

Sreemanti Basu, PhD, Irene Hernandez, MS, Mark Zogg, BS, Hartmut Weiler, PhD, Karen-Sue B. Carlson, MD PhD, Pouneh Kermani, PhD

Blood (2015) 126 (23): 3596.

https://doi.org/10.1182/blood.V126.23.3596.3596

Published: 2015

Journal Articles

Tissue Factor Pathway Inhibitor Modulates Fibrin Deposition In The Brain In a Manner That Is Independent Of Thrombomodulin and Activated Protein C

Susan A. Maroney, DVM, PhD, Paul E. R. Ellery, PhD, Nicholas d Martinez, Mark Zogg, BS, Gary E. Gilbert, M.D., Hartmut Weiler, PhD, Alan E. Mast, MD, PhD

Blood (2013) 122 (21): 2302.

https://doi.org/10.1182/blood.V122.21.2302.2302

Published: 2013

Journal Articles

PAR-4 Deficiency Rescues The Embryonic Lethal Phenotype Of TFPI Null Mice

Paul E. R. Ellery, PhD, Susan A. Maroney, DVM, PhD, Brian C. Cooley, PhD, Mark Zogg, BS, Hartmut Weiler, PhD, Alan E. Mast, MD, PhD

Blood (2013) 122 (21): 199.

https://doi.org/10.1182/blood.V122.21.199.199

Published: 2013

Journal Articles

Thrombin Inhibition Prevents Against Severe Atherosclerosis Progression in Prothrombotic Mice

Henri M.H. Spronk, PhD, Julian I Borissoff, Oliver Soehnlein, Rory Koenen, Rene van Oerle, Sylvia Heeneman, Mat J.A.P. Daemen, Charles T Esmon, PhD, Jay L. Degen, PhD, Hartmut Weiler, PhD, Joanne van Ryn, MSc, PhD, Hugo Ten Cate, MD, PhD

Blood (2012) 120 (21): 103.

https://doi.org/10.1182/blood.V120.21.103.103

Published: 2012

Journal Articles

Factor V Inhibits PAR2-Mediated Lethal Inflammation

Edward J Kerschen, PhD, Hai-Po Helena Liang, Jose A. Fernandez, MD, PhD, Raffaella Toso, PhD, Wolfram Ruf, MD, Rodney M. Camire, PhD, John H. Griffin, PhD, Hartmut Weiler, PhD

Blood (2012) 120 (21): 3360.

https://doi.org/10.1182/blood.V120.21.3360.3360

Published: 2012

Journal Articles

Activated Protein C, Sepsis, and the Innate Immune Response to Infection

Hartmut Weiler, PhD, John H. Griffin, PhD

Blood (2012) 120 (21): SCI-43.

https://doi.org/10.1182/blood.V120.21.SCI-43.SCI-43

Published: 2012

Journal Articles

The Protein C Pathway in Human and Murine Sickle Cell Disease: Alterations in Protein C, Thrombomodulin (TM), and Endothelial Protein C Receptor (EPCR) at Baseline and during Acute Vaso-Occlusion

Yihe Guo, PhD, Teresa Uy, MD, Nancy Wandersee, PhD, J. Paul Scott, MD, Hartmut Weiler, PhD, Sandra Holzhauer, Dawn Retherford, Thomas Foster, Cheryl Hillery, MD

Blood (2008) 112 (11): 538.

https://doi.org/10.1182/blood.V112.11.538.538

Published: 2008

Journal Articles

Structural and Functional Studies to Define the Molecular Basis by Which Platelet Factor 4 (PF4) Increases Survival of Mice in Lipopolysaccharide (LPS)-Induced Endotoxicity

M. Anna Kowalska, PhD, Karine Amirikian, Laurent O. Mosnier, PhD, Hartmut Weiler, PhD, Sriram Krishnaswamy, PhD, Mortimer Poncz, MD

Blood (2008) 112 (11): 19.

https://doi.org/10.1182/blood.V112.11.19.19

Published: 2008

Journal Articles

Fibrinogen Alpha and Gamma Genes and Factor V Leiden in Children with Thromboembolism: Results from Two Family-Based Association Studies

Ulrike Nowak-Gottl, Hartmut Weiler, PhD, Sabine Thedieck, Tanja Seehafer, Monika Stoll

Blood (2008) 112 (11): 3816.

https://doi.org/10.1182/blood.V112.11.3816.3816

Published: 2008

Journal Articles

Epistatic Interaction between Fibrinogen alpha and gamma Genes and Factor V Leiden in Children with Venous Thrombosis: Results from a Family-Based Association Study.

Ulrike Nowak-Gottl, MD, Hartmut Weiler, PhD, Tanja Seehafer, Sabine Thedieck, Monika Stoll, PhD

Blood (2007) 110 (11): 1640.

https://doi.org/10.1182/blood.V110.11.1640.1640

Published: 2007

Journal Articles

Combined Tissue Factor Pathway Inhibitor (TFPI) and Thrombomodulin (TM) Deficiency Produces an Augmented Hypercoagulable State with Tissue Specific Fibrin Deposition.

Susan A. Maroney, DVM, PhD, Brian C. Cooley, PhD, Rashmi Sood, PhD, Hartmut Weiler, PhD, Alan E. Mast, MD PhD

Blood (2007) 110 (11): 265.

https://doi.org/10.1182/blood.V110.11.265.265

Published: 2007

Journal Articles

Mechanisms for Mortality Reduction by Activated Protein C in Severe Sepsis.

Edward J. Kerschen, PhD, Brian C. Cooley, PhD, Francis J. Castellino, PhD, Shaun R. Coughlin, MD, PhD, Jose A. Fernandez, MD, PhD, John H. Griffin, PhD, Hartmut Weiler, PhD

Blood (2006) 108 (11): 1.

https://doi.org/10.1182/blood.V108.11.1.1

Published: 2006

Journal Articles

Impaired Maturation and Survival of T Lymphocytes, B Lymphocytes, and NK Cells in Mice Lacking Gimap5/Ian5.

Ryan D. Schulteis, Xuezhi Dai, Haiyan Chu, PhD, Brandon Edwards, Dipica Haribhai, Calvin B. Williams, MD, PhD, Subramanium Malarkannan, PhD, Hessner J. Martin, PhD, Kwitek E. Anne, PhD, Åke Lernmark, MD, Jack Gorski, PhD, Demin Wang, PhD, Hartmut Weiler, PhD

Blood (2006) 108 (11): 921.

https://doi.org/10.1182/blood.V108.11.921.921

Published: 2006

Journal Articles

Loss of TM-Dependent PC-Activation Predisposes to Diabetic Nephropathy: Potential Role of Endothelial Apoptosis.

Berend Isermann, MD, Madhusudhan Thati, Ilya Vinnikov, MD, Stefanie Herzog, Sina Huntscha, Robert Bünder, MD, Hartmut Weiler, PhD, Angelika Bierhaus, PhD, Peter P. Nawroth, MD

Blood (2005) 106 (11): 1029.

https://doi.org/10.1182/blood.V106.11.1029.1029

Published: 2005

NARROW

Bleeding Diathesis in Mice Lacking JAK2 in Platelets

Dependence on Schwann Cell-Derived Laminin-γ1 Differentiates Early Lymphoid and Myeloid Development

Atomic-Level Dissection of the Polyclonal Immune Response to the Human Platelet Alloantigen, HPA-1a (Pl A1 )

A Murine Model of Type 2N VWD Was Developed By CRISPR/Cas9 Gene Editing and Recapitulates Human Type 2N VWD

Protein C Activation Is the Critical Thrombomodulin Function in Embryonic and Adult Survival in Mice

Crispr/Cas9-Mediated Generation of Mouse Platelets Expressing the Human Platelet Alloantigen, HPA-1a

Physiologic Hematopoiesis Is Dependent on Stromal Expression of Laminin-Î³1

Tissue Factor Pathway Inhibitor Modulates Fibrin Deposition In The Brain In a Manner That Is Independent Of Thrombomodulin and Activated Protein C

PAR-4 Deficiency Rescues The Embryonic Lethal Phenotype Of TFPI Null Mice

Thrombin Inhibition Prevents Against Severe Atherosclerosis Progression in Prothrombotic Mice

Factor V Inhibits PAR2-Mediated Lethal Inflammation

Activated Protein C, Sepsis, and the Innate Immune Response to Infection

The Protein C Pathway in Human and Murine Sickle Cell Disease: Alterations in Protein C, Thrombomodulin (TM), and Endothelial Protein C Receptor (EPCR) at Baseline and during Acute Vaso-Occlusion

Structural and Functional Studies to Define the Molecular Basis by Which Platelet Factor 4 (PF4) Increases Survival of Mice in Lipopolysaccharide (LPS)-Induced Endotoxicity

Fibrinogen Alpha and Gamma Genes and Factor V Leiden in Children with Thromboembolism: Results from Two Family-Based Association Studies

Epistatic Interaction between Fibrinogen alpha and gamma Genes and Factor V Leiden in Children with Venous Thrombosis: Results from a Family-Based Association Study.

Combined Tissue Factor Pathway Inhibitor (TFPI) and Thrombomodulin (TM) Deficiency Produces an Augmented Hypercoagulable State with Tissue Specific Fibrin Deposition.

Mechanisms for Mortality Reduction by Activated Protein C in Severe Sepsis.

Impaired Maturation and Survival of T Lymphocytes, B Lymphocytes, and NK Cells in Mice Lacking Gimap5/Ian5.

Loss of TM-Dependent PC-Activation Predisposes to Diabetic Nephropathy: Potential Role of Endothelial Apoptosis.

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American Society of Hematology

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American Society of Hematology

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