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Journal Articles

Small Molecular Modulators of Histone Demethylases Selectively Inhibits Growth of Hematopoietic Malignancies

Xin Xu, PhD, Wilhelm G Dirks, PhD, Hans G. Drexler, MD PhD, Zhenbo Hu, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3941.
https://doi.org/10.1182/blood-2018-99-112376
Published: 2018
Journal Articles

Normal and Aberrant NKL-Code in B-Cell Development and Lymphoma

Stefan Nagel, PhD, MacLeod A.F. Roderick, PhD, Corinna Meyer, Maren Kaufmann, Hans G. Drexler, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3901.
https://doi.org/10.1182/blood-2018-99-110286
Published: 2018
Journal Articles

SLAMF7 in Primary Effusion Lymphoma, Target for Individualized Therapy?

Hilmar Quentmeier, PhD, Claudia Pommerenke, PhD, Wilhelm G Dirks, PhD, Vivien Hauer, Max Koeppel, PhD, Stefan Nagel, PhD, Michaela Scherr, PhD, Margarete Zaborski, Hans G. Drexler, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5300.
https://doi.org/10.1182/blood-2018-99-110054
Published: 2018
Journal Articles

Epigenetic Modifier Mutations in the LL-100 Panel

Hilmar Quentmeier, PhD, Claudia Pommerenke, PhD, Hans G. Drexler, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5271.
https://doi.org/10.1182/blood-2018-99-110060
Published: 2018
Journal Articles

A Small Molecular Agonist of Histone Demethylase KDM3B Selectively Represses MLL -Rearranged Acute Leukemia

Xin Xu, PhD, Wilhelm G Dirks, PhD, Hans G. Drexler, MD PhD, Zhenbo Hu, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4682.
https://doi.org/10.1182/blood-2018-99-112018
Published: 2018
Journal Articles

Primary Mediastinal Large B-Cell Lymphoma Exhibits Autonomous BCR Signaling and Responds to the Second Generation BTK Inhibitor Acalabrutinib

Marvyn T. Koning, BSc, Rudolf Übelhart, PhD, Sander A.J. van der Zeeuw, BSc, Philip Kluin, MD PhD, Marieke Griffioen, PhD, Hans G. Drexler, MD PhD, Szymon M. Kielbasa, PhD, Marcelo A. Navarrete, MD PhD, Hassan Jumaa, PhD, Hendrik Veelken, MD PhD
Journal: Blood
Blood (2016) 128 (22): 4171.
https://doi.org/10.1182/blood.V128.22.4171.4171
Published: 2016
Journal Articles

Aberrant Expression of Homeobox Gene SIX1 in Hodgkin Lymphoma

Stefan Nagel, PhD, Corinna Meyer, Maren Kaufmann, Roderick MacLeod, Hans G. Drexler, MD PhD
Journal: Blood
Blood (2015) 126 (23): 2638.
https://doi.org/10.1182/blood.V126.23.2638.2638
Published: 2015
Journal Articles

A New Entity of Acute Myeloid Leukemia Driven By Epigenetic and Somatic Dis-Regulation of Uncx , a Novel Homeobox Transcription Factor Gene

Giulia Daniele, Clelia Tiziana Storlazzi, Cristina Papayannidis, MD PhD, Ilaria Iacobucci, PhD, Angelo Lonoce, Margherita Perricone, Mariana Lomiento, Fabiana Mammoli, Elena Marasco, Vilma Mantovani, Hilmar Quentmeier, PhD, Giorgia Simonetti, PhD, Antonella Padella, Vincenzo Franza, Hans G. Drexler, MD PhD, Jie Ding, PhD, Orazio Palumbo, Massimo Carella, Niroshan Nadarajah, M.Sc., Renè Massimiliano Marsano, Antonio Palazzo, Emanuela Ottaviani, Carmen Baldazzi, PhD, Nicoletta Testoni, Sergio Ferrari, MD PhD, Giovanni Martinelli, MD PhD
Journal: Blood
Blood (2015) 126 (23): 1356.
https://doi.org/10.1182/blood.V126.23.1356.1356
Published: 2015
Journal Articles

Inhibition Of PI3K/mTOR Overcomes Nilotinib Resistance In BCR-ABL1 Positive Leukemia Cells

Jie Ding, PhD, Julia Romani, Margarete Zaborski, Roderick AF MacLeod, PhD, Stefan Nagel, PhD, Hans G. Drexler, MD, PhD, Hilmar Quentmeier, PhD
Journal: Blood
Blood (2013) 122 (21): 4906.
https://doi.org/10.1182/blood.V122.21.4906.4906
Published: 2013
Journal Articles

NKL Homeobox Gene MSX1 Reactivates An Oncogenic Network In Lymphoid and Myeloid Malignancies

Stefan Nagel, PhD, Stefan Ehrentraut, PhD, Corinna Meyer, Maren Kaufmann, Hans G. Drexler, MD, PhD, Roderick AF MacLeod, PhD
Journal: Blood
Blood (2013) 122 (21): 3765.
https://doi.org/10.1182/blood.V122.21.3765.3765
Published: 2013
Journal Articles

T(8;9)(p22;p24)/PCM1-JAK2 Activates SOCS2 and SOCS3 Via STAT5

Stefan Ehrentraut, Stefan Nagel, PhD, Michaela Scherr, Bjoern Schneider, Hilmar Quentmeier, PhD, Robert Geffers, PhD, Monika Prochorec-Sobieszek, Rhett P Ketterling, MD, Ryan A Knudson, Andrew L. Feldman, MD, Marshall Kadin, Hans G. Drexler, MD, PhD, Roderick AF MacLeod
Journal: Blood
Blood (2012) 120 (21): 1567.
https://doi.org/10.1182/blood.V120.21.1567.1567
Published: 2012
Journal Articles

Aberrant Chromatin Modifications Mediate Ectopic Expression of Homeobox Gene NKX2-1 in B-Cell Lymphoma

Stefan Nagel, PhD, Corinna Meyer, Maren Kaufmann, Roderick AF MacLeod, PhD, Hans G. Drexler, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 3494.
https://doi.org/10.1182/blood.V120.21.3494.3494
Published: 2012
Journal Articles

Transcriptional Deregulation of Homeobox Gene ZHX2 in Hodgkin Lymphoma

Stefan Nagel, PhD, Björn Schneider, PhD, Corinna Meyer, Maren Kaufmann, Roderick AF MacLeod, PhD, Hans G. Drexler, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 2629.
https://doi.org/10.1182/blood.V118.21.2629.2629
Published: 2011
Journal Articles

CRLF2 and JAK2 Mutations: Occurrence and Function In Pre-B ALL Cell Lines

Hilmar Quentmeier, PhD, Sonja Eberth, PhD, Roderick AF MacLeod, PhD, Stefan Nagel, PhD, Julia Romani, Margarete Zaborski, Hans G. Drexler, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 5109.
https://doi.org/10.1182/blood.V116.21.5109.5109
Published: 2010
Journal Articles

Transcriptional Regulation of Oncogenic MEF2C In T-Cell Acute Lymphoblastic Leukemia (T-ALL).

Stefan Nagel, PhD, Letizia Venturini, PhD, Corinna Meyer, Maren Kaufmann, Michaela Scherr, PhD, Hans G. Drexler, MD, PhD, Roderick AF MacLeod, PhD
Journal: Blood
Blood (2010) 116 (21): 3636.
https://doi.org/10.1182/blood.V116.21.3636.3636
Published: 2010
Journal Articles

Induction of Apoptosis In Imatinib-Resistant BCR-ABL1 -Positive Leukemia Cell Lines by Bortezomib

Hilmar Quentmeier, PhD, Sonja Eberth, PhD, Julia Romani, Margarete Zaborski, Hans G. Drexler, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 4469.
https://doi.org/10.1182/blood.V116.21.4469.4469
Published: 2010
Journal Articles

Activation of Paired-Homeobox Gene PITX1 by Del(5)(q31) In T-Cell Acute Lymphoblastic Leukemia (T-ALL)

Stefan Nagel, PhD, Letizia Venturini, PhD, Grzegorz K. Przybylski, MD, Piotr Grabarczyk, PhD, Björn Schneider, PhD, Corinna Meyer, Maren Kaufmann, Christian A. Schmidt, MD, Michaela Scherr, PhD, Hans G. Drexler, MD, PhD, Roderick AF MacLeod, PhD
Journal: Blood
Blood (2010) 116 (21): 4644.
https://doi.org/10.1182/blood.V116.21.4644.4644
Published: 2010
Journal Articles

Micro-RNA Gene Deregulation by Chromosome Translocations with Fragile Genomic Regions in B-Cell Lymphoma Cells

Bjoern Schneider, PhD, Stefan Nagel, PhD, Maren Kaufmann, Hans G. Drexler, MD, Roderick A.F. MacLeod, PhD
Journal: Blood
Blood (2008) 112 (11): 786.
https://doi.org/10.1182/blood.V112.11.786.786
Published: 2008
Journal Articles

Comprehensive Analysis of Homeobox Genes in Hodgkin Lymphoma Cell Lines Identified Dysregulated Expression of HOXB9 Mediated by Constitutive Active ERK5 Signalling Pathway and BMI1.

Stefan Nagel, PhD, Cristof Burek, PhD, Letizia Venturini, PhD, Michaela Scherr, PhD, Hilmar Quentmeier, PhD, Corinna Meier, Andreas Rosenwald, MD, Hans G. Drexler, MD, Roderick A.F. MacLeod, PhD
Journal: Blood
Blood (2006) 108 (11): 471.
https://doi.org/10.1182/blood.V108.11.471.471
Published: 2006
Journal Articles

Analysis of MLL Amplification and 5q Deletions in AML/MDS Cell Lines Identifies Novel Targets.

Bjoern Schneider, Stefan Nagel, PhD, Maren Kaufmann, Hilmar Quentmeier, PhD, Yoshinobu Matsuo, PhD, Hans G. Drexler, MD, Roderick A.F. MacLeod, PhD
Journal: Blood
Blood (2006) 108 (11): 1424.
https://doi.org/10.1182/blood.V108.11.1424.1424
Published: 2006