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Hakim Djaballah
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Journal Articles

MYC-Dependent PI3K and MCL-1 Feedbacks Attenuate BET Inhibitors Activity in Diffuse Large B-Cell Lymphoma

Enrico Derenzini, MD PhD, Patrizia Mondello, MD MSc, Yuxuan Liu, PhD, Mary Scallion, Zahra Asgari, John Philip, Patrick Hilden, MS, Hakim Djaballah, PhD, Ouathek Ouerfelli, PhD, Elisa de Stanchina, PhD, Venkatraman Seshan, PhD, Ronald Hendrickson, PhD, Andrew D. Zelenetz, Anas Younes, MD
Journal: Blood
Blood (2016) 128 (22): 294.
https://doi.org/10.1182/blood.V128.22.294.294
Published: 2016
Journal Articles

Thioguanine Combined with Decitabine Can Overcome Resistance to Hypomethylating Agents: Final Results of a Phase I Trial of a Pharmacodynamically-Conceived Thioguanine/Decitabine Combination in Patients with Advanced Myeloid Malignancies

Daniel J. Lee, MD, Todd L. Rosenblat, MD MS, Mark Lawrence Heaney, MD PhD, Joseph G. Jurcic, MD, Azra Raza, MD, Kristina Gazivoda, Katherine Harwood, Ryan Shelton, Hakim Djaballah, PhD, Joseph M. Scandura, MD PhD, Anthony Letai, MD PhD, Mark G. Frattini, MD PhD
Journal: Blood
Blood (2016) 128 (22): 2816.
https://doi.org/10.1182/blood.V128.22.2816.2816
Published: 2016
Journal Articles

A Phase I Trial of a Pharmacodynamically-Conceived Decitabine and Thioguanine Combination in Patients with Advanced Myeloid Malignancies

Todd Rosenblat, MD, Mark L. Heaney, MD PhD, Joseph G Jurcic, MD, Azra Raza, MD, John G. Mears, MD, Ruth Santos, BS, Diana Carrillo, BS, David Shum, MS, Jacquelyn Gonzales, BSN, RN, Kevin Zikaras, BS, Martin Santos, BS, Rong Zhang, MS, Glorymar Ibanezs, MS, Leah Hogdal, BA, Jennifer Crombie, MD, Hakim Djaballah, PhD, Joseph M. Scandura, MD PhD, Anthony G. Letai, MD PhD, Mark G. Frattini, MD PhD
Journal: Blood
Blood (2014) 124 (21): 974.
https://doi.org/10.1182/blood.V124.21.974.974
Published: 2014
Journal Articles

Preclinical Assessment of a Novel CDC7 Inhibitor: Genomewide RNAi Screening Identifies Unique Synergetic and Resistance Genes,

Nancy Liu-Sullivan, Bhavneet Bhinder, David Shum, Christina Ramirez, Constantin Radu, Hakim Djaballah, PhD, Mark G. Frattini, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 3570.
https://doi.org/10.1182/blood.V118.21.3570.3570
Published: 2011
Journal Articles

Clinical Implementation of a Novel High-Throughput Screen of Primary Leukemia Cells to Customize Therapy for Relapsed/Refractory Acute Myeloid Leukemia (AML).

Kristen M O'Dwyer, M.D., David Shum, M.S., Mark Heaney, MD, PhD, Renier J. Brentjens, MD, PhD, Peter Maslak, MD, Joseph G Jurcic, MD, Hakim Djaballah, Ph.D., Mark G. Frattini, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 2657.
https://doi.org/10.1182/blood.V114.22.2657.2657
Published: 2009
Journal Articles

Discovery and Validation of a Novel Class of Small Molecule Inhibitors of the CDC7 Kinase: Modulation of Tumor Cell Growth in Vitro and In Vivo .

Mark G. Frattini, MD, PhD, David Shum, M.S., Kristen M O'Dwyer, M.D., Renier J. Brentjens, MD, PhD, Peter Maslak, MD, Mark Heaney, MD, PhD, Joseph G Jurcic, MD, Hakim Djaballah, Ph.D., Thomas J Kelly, M.D., Ph.D.
Journal: Blood
Blood (2009) 114 (22): 3771.
https://doi.org/10.1182/blood.V114.22.3771.3771
Published: 2009
Journal Articles

Small Molecule Inhibition of Cdc7, a Key Cell Cycle Regulator and Novel Therapeutic Target, Successfully Inhibits Leukemia Cell Growth in Vitro and in Vivo

Mark G. Frattini, MD, PhD, David Shum, M.S., Kristen M O’Dwyer, M.D., Renier J. Brentjens, MD, PhD, Ray Yeh, Ph.D., Peter Maslak, MD, Mark Lawrence Heaney, MD, PhD, Joseph Jurcic, MD, Hakim Djaballah, Ph.D., Thomas J Kelly, M.D., Ph.D.
Journal: Blood
Blood (2008) 112 (11): 2668.
https://doi.org/10.1182/blood.V112.11.2668.2668
Published: 2008