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Journal Articles

Concomitant Targeting of FLT3 and BTK with CG'806 Overcomes FLT3-Inhibitor Resistance through Inhibition of Autophagy

Weiguo Zhang, MD PhD, Guopan Yu, MD, PhD, Hongying Zhang, MD, PhD, Charlie Ly, BS, Bin Yuan, Vivian Ruvolo, MS, Sujan Piya, PhD, Seemana Bhattacharya, PhD, Qi Zhang, PhD, Gautam Borthakur, MD, Venkata Lokesh Battula, PhD, Marina Y. Konopleva, MD PhD, William G Rice, PhD, Michael Andreeff, MD PhD

Blood (2018) 132 (Supplement 1): 2635.

https://doi.org/10.1182/blood-2018-99-116643

Published: 2018

Journal Articles

CG '806, a Novel Pan-FLT3/BTK Multi-Kinase Inhibitor, Induces Cell Cycle Arrest, Apoptosis or Autophagy in AML Cells Depending on FLT3 Mutation Status

Guopan Yu, MD, PhD, Weiguo Zhang, MD PhD, Charlie Ly, BS, Hongying Zhang, MD, William Rice, PhD, Michael Andreeff, MD PhD

Blood (2017) 130 (Supplement 1): 4629.

https://doi.org/10.1182/blood.V130.Suppl_1.4629.4629

Published: 2017

Journal Articles

The Pan-FLT3/BTK Multi-Kinase Inhibitor CG '806 Induces AML Killing in FLT-Mutant and Wild Type Cells, and Exerts Synergistic Pro-Apoptotic Effects with Concomitant Targeting of Anti-Apoptotic Bcl-2 and/or Mcl-1

Charlie Ly, BS, Weiguo Zhang, MD PhD, Guopan Yu, MD, PhD, Hong Mu, MD PhD, Hongying Zhang, MD, William Rice, PhD, Michael Andreeff, MD PhD

Blood (2017) 130 (Supplement 1): 3348.

https://doi.org/10.1182/blood.V130.Suppl_1.3348.3348

Published: 2017

Journal Articles

APP Gene Is Correlated with C-KIT Mutations and Indicates Poor Disease Outcome in AML1-ETO-Positive Acute Myeloid Leukemia

Guopan Yu, MD, Ling Jiang, MDPhD, Fan Yi Meng, MD, Changxin Yin, Zhixiang Wang, MD, Hongsheng Zhou, MDPhD, Xuejie Jiang, MDPhD, Qingxiu Zhong, MD, Rui Cao, Libin Liao

Blood (2014) 124 (21): 942.

https://doi.org/10.1182/blood.V124.21.942.942

Published: 2014

Journal Articles

Molecular Mechanisms of EML in AML1/ETO+ AML and Its Targeting Treatments

Fan Yi Meng, MD, Ling Jiang, MD PhD, Qingxiu Zhong, MD, Li Chun Wang, MD, Guopan Yu, MD, Xinhua Zhu, MD

Blood (2014) 124 (21): 5953.

https://doi.org/10.1182/blood.V124.21.5953.5953

Published: 2014

Journal Articles

A Two-Year Follow-Up Of a Prospective Study Of Intensified Conditioning Regimen With High-Dose-Etoposide Allogeneic Hematopoietic Stem Cell Transplantation For Adult Acute Lymphoblastic Leukemia In China

Hongsheng Zhou, Zhiping Fan, Fen Huang, Yu Zhang, Min Dai, PhD, Na Xu, Guopan Yu, MD, Dan Xu, Qianli Jiang, Jing Sun, MD, Qifa Liu, MD

Blood (2013) 122 (21): 4570.

https://doi.org/10.1182/blood.V122.21.4570.4570

Published: 2013

Journal Articles

Graft-Versus-Host Disease Following Myeloablative Busulfan Plus Fludarabine and Busulfan Plus Cyclophosphamide For Allogeneic Hematopoietic Stem Cell Transplantation In Acute Myeloid Leukemia In First Complete Remission

Qifa Liu, MD, Hui Liu, Daihong Liu, Yongrong Lai, MD, Jing Sun, MD, Chaoyang Song, Yu Zhang, Yang Xiao, MD, Fen Huang, MD, Hongsheng Zhou, Zhiping Fan, Xutao Guo, M.D., Danian Nie, MD, Guopan Yu, MD&M Sci, Xiaojun Huang

Blood (2013) 122 (21): 3290.

https://doi.org/10.1182/blood.V122.21.3290.3290

Published: 2013

Journal Articles

Molecular Mechanism Of Regulation Of Extramedullary Infiltration In AML1/ETO Positive Acute Myeloid Leukemia By APP/ERK/MMP-2

Guopan Yu, MD, Fan Yi Meng, MD, Ling Jiang, MD/PH.D, Changxin Yin, MD, Zhixiang Wang, MD, Hongsheng Zhou, Xuejie Jiang, MD/PH.D, Lingxiu Zhang, MD, Rui Cao, Libin Liao, MB

Blood (2013) 122 (21): 3769.

https://doi.org/10.1182/blood.V122.21.3769.3769

Published: 2013

Journal Articles

Continuous Intravenous Injection Of Mesna Can Reduce Acute Hemorrhagic Cystitis Occurrence Rate In Hematopoietic Stem Cell Transplantation: 359 Allo-HSCT Cases Report

Blood (2013) 122 (21): 4556.

https://doi.org/10.1182/blood.V122.21.4556.4556

Published: 2013

NARROW

Concomitant Targeting of FLT3 and BTK with CG'806 Overcomes FLT3-Inhibitor Resistance through Inhibition of Autophagy

CG '806, a Novel Pan-FLT3/BTK Multi-Kinase Inhibitor, Induces Cell Cycle Arrest, Apoptosis or Autophagy in AML Cells Depending on FLT3 Mutation Status

The Pan-FLT3/BTK Multi-Kinase Inhibitor CG '806 Induces AML Killing in FLT-Mutant and Wild Type Cells, and Exerts Synergistic Pro-Apoptotic Effects with Concomitant Targeting of Anti-Apoptotic Bcl-2 and/or Mcl-1

APP Gene Is Correlated with C-KIT Mutations and Indicates Poor Disease Outcome in AML1-ETO-Positive Acute Myeloid Leukemia

Molecular Mechanisms of EML in AML1/ETO+ AML and Its Targeting Treatments

A Two-Year Follow-Up Of a Prospective Study Of Intensified Conditioning Regimen With High-Dose-Etoposide Allogeneic Hematopoietic Stem Cell Transplantation For Adult Acute Lymphoblastic Leukemia In China

Graft-Versus-Host Disease Following Myeloablative Busulfan Plus Fludarabine and Busulfan Plus Cyclophosphamide For Allogeneic Hematopoietic Stem Cell Transplantation In Acute Myeloid Leukemia In First Complete Remission

Molecular Mechanism Of Regulation Of Extramedullary Infiltration In AML1/ETO Positive Acute Myeloid Leukemia By APP/ERK/MMP-2

Continuous Intravenous Injection Of Mesna Can Reduce Acute Hemorrhagic Cystitis Occurrence Rate In Hematopoietic Stem Cell Transplantation: 359 Allo-HSCT Cases Report

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American Society of Hematology

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ASH Publications

American Society of Hematology

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