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Grant D. Trobridge, PhD
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Journal Articles

Rapid Expansion of Gene-Marked Lymphocytes in X-SCID Dogs after AMD3100+G-CSF-Based Hematopoietic Stem/Progenitor Cell Mobilization and Intravenous Injection of a Common γ-Chain Expressing Foamy Viral Vector

Free
Frieda Chan, PhD, Olivier Humbert, PhD, Troy Torgerson, MD PhD, Nicholas Hubbard, Patricia O'Donnell, Daniel R Humphrys, B.S., Jennifer E Adair, PhD, Peter Felsburg, Grant D. Trobridge, PhD, Andrew M. Scharenberg, MD, David J. Rawlings, MD, Hans-Peter Kiem, MD FACP
Journal: Blood
Blood (2016) 128 (22): 1348.
https://doi.org/10.1182/blood.V128.22.1348.1348
Published: 2016
Journal Articles

A Point-of-Care Platform for Hematopoietic Stem Cell Gene Therapy

Free
Jennifer E Adair, PhD, Kevin G Haworth, PhD, Guy Sauvageau, MD, PhD, Shelly Heimfeld, PhD, Jonah D Hocum, B.S., Grant D. Trobridge, PhD, Hans-Peter Kiem, MD
Journal: Blood
Blood (2015) 126 (23): 4416.
https://doi.org/10.1182/blood.V126.23.4416.4416
Published: 2015
Journal Articles

In Vivo Selection Unmasks a Dormant Pool of Repopulating Hematopoietic Clones

Free
Jennifer E Adair, PhD, Lauren E Schefter, B.A., Daniel R Humphrys, B.S., Kevin G Haworth, PhD, Jonah D Hocum, B.S., Grant D. Trobridge, PhD, Hans-Peter Kiem, MD
Journal: Blood
Blood (2015) 126 (23): 242.
https://doi.org/10.1182/blood.V126.23.242.242
Published: 2015
Journal Articles

Pgk-Mediated Expression of Common Gamma Chain Is More Effective Than EF1a for Therapeutic Immune Reconstitution of X-SCID Dogs after In Vivo Gene Therapy with Foamy Virus Vector

Free
Olivier Humbert, PhD, Christopher R Burtner, PhD, Patricia O'Donnell, Daniel R Humphrys, B.S., Nicholas Hubbard, Frieda Chan, PhD, Jennifer E Adair, PhD, Grant D. Trobridge, PhD, Troy Torgerson, MD PhD, Andrew M. Scharenberg, MD, David J. Rawlings, MD, Peter Felsburg, Hans-Peter Kiem, MD
Journal: Blood
Blood (2015) 126 (23): 262.
https://doi.org/10.1182/blood.V126.23.262.262
Published: 2015
Journal Articles

Robust Therapeutic Expression of the Common Gamma Chain with the Human Pgk Promoter Using Foamy Virus in Vivo Gene Therapy in a Canine Model of Severe Combined Immunodeficiency

Free
Christopher R Burtner, PhD, Olivier Humbert, PhD, Patricia O'Donnell, Nicholas Hubbard, Daniel Humphrys, Jennifer E Adair, PhD, Grant D Trobridge, PhD, Troy R Torgerson, MD PhD, Andrew M Scharenberg, MD, David Rawlings, MD, Peter J Felsburg, VMD, PhD, Hans-Peter Kiem, MD
Journal: Blood
Blood (2014) 124 (21): 4794.
https://doi.org/10.1182/blood.V124.21.4794.4794
Published: 2014
Journal Articles

Efficient MGMTP140K-Mediated In Vivo Selection and Chemoprotection of Long-Term Repopulating Cells in Nonhuman Primates Following Reduced Intensity Conditioning.

Free
Brian C Beard, PhD, Grant D Trobridge, PhD, Jeannine S McCune, Hans-Peter Kiem, MD
Journal: Blood
Blood (2009) 114 (22): 3572.
https://doi.org/10.1182/blood.V114.22.3572.3572
Published: 2009
Journal Articles

Correction of Fanconi Anemia Group A in Primary Human and Murine Hematopoietic Progenitors with a Clinical Lentiviral Vector

Free
Jason Taylor, MD, PhD, Grant D Trobridge, PhD, Martin Wohlfahrt, Sylvia Chien, Xin Zhao, MD, Brian C Beard, PhD, Hans-Peter Kiem, MD, Pamela S. Becker, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 2357.
https://doi.org/10.1182/blood.V112.11.2357.2357
Published: 2008
Journal Articles

Efficient Gene Marking with a Clinical Gammaretrovirus Vector Expressing MGMTP140K in Baboons and Macaques

Free
Brian C Beard, PhD, Megan L Welsh, MS, Grant D Trobridge, PhD, Hans-Peter Kiem, MD
Journal: Blood
Blood (2008) 112 (11): 3535.
https://doi.org/10.1182/blood.V112.11.3535.3535
Published: 2008
Journal Articles

Transduction of Macaque Hematopoietic Repopulating Cells with Lenti and Foamy Retroviral Vectors with MGMT Selection Cassettes To Evaluate AIDS Gene Therapy Strategies.

Free
Grant D. Trobridge, PhD, Brian C. Beard, Ph.D., David Dickerson, Christina Gooch, Philip Olsen, James Fletcher, Ming-Jie Li, Ph.D., Shiu-Lok Hu, Ph.D., John J. Rossi, Ph.D., Hans-Peter Kiem, M.D.
Journal: Blood
Blood (2006) 108 (11): 3273.
https://doi.org/10.1182/blood.V108.11.3273.3273
Published: 2006
Journal Articles

A Non-Human Primate Model To Study Anti-HIV Gene Therapy Strategies.

Free
Grant D. Trobridge, PhD, Karen Beagles, PhD, Brian Beard, PhD, Ming-Jie Li, PhD, Jiing-Kuan Yee, PhD, John Rossi, PhD, Shiu-lok Hu, PhD, Hans-Peter Kiem, MD
Journal: Blood
Blood (2005) 106 (11): 3046.
https://doi.org/10.1182/blood.V106.11.3046.3046
Published: 2005
Journal Articles

Large Scale Analysis of Foamy Virus Vector Integration Sites in Human CD34+ Cells.

Free
Grant D. Trobridge, PhD, Daniel G. Miller, MD, PhD, Michael A. Jacobs, PhD, James M. Allen, PhD, Erik Olson, Hans-Peter Kiem, MD, Rajinder Kaul, PhD, David W. Russell, MD, PhD
Journal: Blood
Blood (2004) 104 (11): 496.
https://doi.org/10.1182/blood.V104.11.496.496
Published: 2004