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Journal Articles

Targeting Critical Kinases and Anti-Apoptotic Molecules Overcomes Steroid Resistance in Infant MLL-Rearranged Leukemia

Anne Pieta De Groot, Yoriko Saito, MD, Eiryo Kawakami, Mari Hashimoto, Yuki Aoki, Rintaro Ono, MD PhD, Ikuko Ogahara, Saera Fujiki, Akiko Kaneko, Takashi Watanabe, PhD, Masatoshi Takagi, MD PhD, Daisuke Tomizawa, MD PhD, Katsuyoshi Koh, MD, Mariko Eguchi, MD, Eiichi Ishii, MD PhD, Osamu Ohara, Leonard Shultz, PhD, Shuki Mizutani, Fumihiko Ishikawa, MD PhD

Blood (2019) 134 (Supplement_1): 3885.

https://doi.org/10.1182/blood-2019-129719

Published: 2019

Journal Articles

Membrane-Bound Human Stem Cell Factor Promotes Differentiation of Human Granulocytes and Mast Cells In Vivo,

Shinsuke Takagi, MD, Yoriko Saito, MD, Atsushi Hijikata, PhD, Satoshi Tanaka, Takashi Watanabe, PhD, Haruhiko Koseki, MD, PhD, Osamu Ohara, PhD, Takashi Saito, PhD, Shuichi Taniguchi, MD, PhD, Leonard Shultz, PhD, Fumihiko Ishikawa, MD, PhD

Blood (2011) 118 (21): 3419.

https://doi.org/10.1182/blood.V118.21.3419.3419

Published: 2011

Journal Articles

Hematopoietic Stem Cells Are Primarily Involved In Pathogenesis of Chronic Lymphocytic Leukemia.

Yoshikane Kikushige, MD, Fumihiko Ishikawa, MD, PhD, Toshihiro Miyamoto, MD, PhD, Koichi Akashi, MD., PhD.

Blood (2010) 116 (21): 4604.

https://doi.org/10.1182/blood.V116.21.4604.4604

Published: 2010

Journal Articles

Cell Cycle Entry Potentiates Elimination of Chemotherapy-Resistant Human AML Stem Cells.

Yoriko Saito, MD, Naoyuki Uchida, MD, PhD, Satoshi Tanaka, Mariko Tomizawa-Murasawa, Nahoko Suzuki, Shinsuke Takagi, MD, Yuho Najima, MD, Yuki Aoki, MD, Akiko Sone, Atsushi Wake, MD, Shuichi Taniguchi, MD, PhD, Leonard D. Shultz, PhD, Fumihiko Ishikawa, MD, PhD

Blood (2009) 114 (22): 1422.

https://doi.org/10.1182/blood.V114.22.1422.1422

Published: 2009

Journal Articles

Development of Novel Stem Cell Transplantation and Gene-Immunotherapy Using WT1-Specific T-Cell Receptor Gene.

Toshiki Ochi, MD, Hiroshi Fujiwara, MD, PhD, Kozo Nagai, MD, Toshiaki Shirakata, MD, PhD, Kiyotaka Kuzushima, MD, PhD, Sachiko Okamoto, PhD, Junichi Mineno, PhD, Hiroshi Shiku, MD, PhD, Hidetoshi Ozawa, PhD, Fumihiko Ishikawa, MD, PhD, Masaki Yasukawa, MD, PhD

Blood (2009) 114 (22): 3028.

https://doi.org/10.1182/blood.V114.22.3028.3028

Published: 2009

Journal Articles

Hematopoietic Stem Cells Are Primarily Involved in Pathogenesis of Chronic Lymphocytic Leukemia

YoshiKane KiKushige, MD, Toshihiro Miyamoto, MD, PhD, Tadafumi Iino, MD, Fumihiko Ishikawa, MD, PhD, Koichi Akashi, MD, PhD

Blood (2008) 112 (11): 29.

https://doi.org/10.1182/blood.V112.11.29.29

Published: 2008

Journal Articles

Analysis of Idiopathic Myelofibrosis Initiating Cell in NOD/SCID/IL2rgKO Mice

Noriyuki Saito, MD, Fumihiko Ishikawa, MD, PhD, Kazuya Shimoda, MD, PhD, Shuro Yoshida, MD, PhD, Yoriko Saito, MD, Mitsuhiro Fukata, MD, Chika Iwamoto, Noriaki Kawano, MD, PhD, Leonard Shultz, PhD, Mine Harada, MD, Koichi Akashi, MD, PhD

Blood (2008) 112 (11): 3715.

https://doi.org/10.1182/blood.V112.11.3715.3715

Published: 2008

Journal Articles

Transplantation of Primary Human CD34+CD38 - Hematopoietic Stem Cells Recapitulates Idiopathic Myelofibrosis in the NOD/scid/IL2rgKO Mice.

Noriyuki Saito, MD, Fumihiko Ishikawa, MD/PhD, Kazuya Shimoda, MD/PhD, Shuro Yoshida, MD/PhD, Yoriko Saito, MD, Mitsuhiro Fukata, MD, Noriaki Kawano, MD/PhD, Leonard D. Shulz, PhD, Koichi Akashi, MD/PhD, Mine Harada, MD

Blood (2007) 110 (11): 260.

https://doi.org/10.1182/blood.V110.11.260.260

Published: 2007

Journal Articles

Establishment of Novel Disease Models for Human Acute Type ATL and HTLV-I Carrier Using NOD-scid/IL2rg null Mouse.

Chika Iwamoto, Fumihiko Ishikawa, MD, PhD, Noriaki Kawano, MD, PhD, Noriyuki Saito, MD, Shen M. Yang, MD, PhD, Mitsuhiro Fukata, MD, Yoriko Saito, MD, PhD, Leonard D. Shultz, PhD, Masao Matsuoka, MD, PhD, Mine Harada, MD, PhD

Blood (2007) 110 (11): 2797.

https://doi.org/10.1182/blood.V110.11.2797.2797

Published: 2007

Journal Articles

Human AML Stem Cells Remain Quiescent and Exhibit Chemotherapy Resistance within the Bone Marrow Endosteal Region.

Yoriko Saito, MD, Shuro Yoshida, MD/PhD, Noriyuki Saito, MD, Mitsuhiro Fukata, MD, Hidetoshi Ozawa, MSc, Takehiko Doi, MD/PhD, Toshihiro Miyamoto, MD/PhD, Koichi Ohshima, MD/PhD, Naoyuki Uchida, MD/PhD, Shuichi Taniguchi, MD/PhD, Koichi Akashi, MD/PhD, Mine Harada, MD, Leonard D. Shultz, PhD, Fumihiko Ishikawa, MD/PhD

Blood (2007) 110 (11): 780.

https://doi.org/10.1182/blood.V110.11.780.780

Published: 2007

Journal Articles

Highly Purified Hematopoietic Stem Cell Can Generate Cardiomyocytes Via Myeloid Progenitors through Cell Fusion.

Mitsuhiro Fukata, MD, Fumihiko Ishikawa, MD, PhD, Hideki Shimazu, MD, Ryu Nakamura, Kazuya Shimoda, MD, PhD, Koichi Akashi, MD, PhD, Shultz D. Leonard, MD, PhD, Mine Harada, MD, PhD

Blood (2006) 108 (11): 279.

https://doi.org/10.1182/blood.V108.11.279.279

Published: 2006

Journal Articles

Expression of CD10 and CD7 Defines Distinct In Vivo Lymphoid Reconstituting Capacity within Human Cord Blood CD34+CD38-Cells.

Shuro Yoshida, MD, PhD, Fumihiko Ishikawa, MD/PhD, Leonard D. Shultz, PhD, Noriyuki Saito, MD, Mitsuhiro Fukata, MD, Kazuya Shimoda, MD/PhD, Koichi Akashi, MD/PhD, Mine Harada, MD

Blood (2006) 108 (11): 3184.

https://doi.org/10.1182/blood.V108.11.3184.3184

Published: 2006

Journal Articles

Xenotransplantation of Primary CD34+CD38- Hematopoietic Stem Cells Results in an In Vivo Model of Idiopathic Myelofibrosis.

Noriyuki Saito, MD, Fumihiko Ishikawa, MD/PhD, Kazuya Shimoda, MD/PhD, Shuro Yoshida, MD/PhD, Yoriko Saito, MD, Noriaki Kawano, MD/PhD, Leonard D. Shulz, PhD, Koichi Akashi, MD/PhD, Mine Harada, MD

Blood (2006) 108 (11): 666.

https://doi.org/10.1182/blood.V108.11.666.666

Published: 2006

Journal Articles

Human Conventional and Plasmacytoid Dendritic Cells Can Originate from Both Lymphoid and Myeloid Progenitors in a New Humanized Mouse System.

Fumihiko Ishikawa, MD, PhD, Tadafumi Iino, MD, Hiroaki Niiro, MD, PhD, Shuro Yoshida, MD, Toshihiro Miyamoto, MD, PhD, Hirokazu Shigematsu, MD, PhD, Leonard D. Shultz, PhD, Mine Harada, MD, Koichi Akashi, MD, PhD

Blood (2005) 106 (11): 2273.

https://doi.org/10.1182/blood.V106.11.2273.2273

Published: 2005

Journal Articles

Long-Term Engraftment and Self-Renewal of AML Stem Cells in the Newborn NOD-scid/IL2rgnull Immunodeficient Mouse Model.

Shuro Yoshida, MD, Fumihiko Ishikawa, MD, PhD, Masaki Yasukawa, MD, PhD, Toshihiro Miyamoto, MD, PhD, Goichi Yoshimoto, MD, Noriaki Kawano, MD, Kazuya Shimoda, MD, Koichi Akashi, MD, PhD, Leonard D. Shultz, PhD, Mine Harada, MD

Blood (2005) 106 (11): 1261.

https://doi.org/10.1182/blood.V106.11.1261.1261

Published: 2005

Journal Articles

In Vivo Generation and the Mechanism of Bone Marrow- and Cord Blood-Derived Cardiomyocytes.

Fumihiko Ishikawa, MD, PhD, Leonard D. Shultz, PhD, Mitsuhifo Fukata, MD, Shuro Yoshida, MD, Masaki Yasukawa, MD, PhD, Mine Harada, MD

Blood (2004) 104 (11): 2695.

https://doi.org/10.1182/blood.V104.11.2695.2695

Published: 2004

Journal Articles

Neonatal NOD/SCID/IL2rg-Null Mice Support the Functional Development of Human Hematopoietic and Immune Systems.

Fumihiko Ishikawa, MD, PhD, Masaki Yasukawa, MD, PhD, Bonnie Lyons, PhD, Shuro Yoshida, MD, Leonard D. Shultz, PhD, Mine Harada, MD

Blood (2004) 104 (11): 2781.

https://doi.org/10.1182/blood.V104.11.2781.2781

Published: 2004

Journal Articles

Human CB-Derived Cells Give Rise to Insulin-Producing-Cells in Xenogeneic Hosts.

Shuro Yoshida, MD, Fumihiko Ishikawa, MD, PhD, Noriaki Kawano, MD, Hua Zhang, MD, Yuan Kong, MD, Kazuya Shimoda, MD, Leonard D. Shultz, PhD, Mine Harada, MD

Blood (2004) 104 (11): 3603.

https://doi.org/10.1182/blood.V104.11.3603.3603

Published: 2004

NARROW

Targeting Critical Kinases and Anti-Apoptotic Molecules Overcomes Steroid Resistance in Infant MLL-Rearranged Leukemia

Membrane-Bound Human Stem Cell Factor Promotes Differentiation of Human Granulocytes and Mast Cells In Vivo,

Hematopoietic Stem Cells Are Primarily Involved In Pathogenesis of Chronic Lymphocytic Leukemia.

Cell Cycle Entry Potentiates Elimination of Chemotherapy-Resistant Human AML Stem Cells.

Development of Novel Stem Cell Transplantation and Gene-Immunotherapy Using WT1-Specific T-Cell Receptor Gene.

Hematopoietic Stem Cells Are Primarily Involved in Pathogenesis of Chronic Lymphocytic Leukemia

Analysis of Idiopathic Myelofibrosis Initiating Cell in NOD/SCID/IL2rgKO Mice

Transplantation of Primary Human CD34+CD38 - Hematopoietic Stem Cells Recapitulates Idiopathic Myelofibrosis in the NOD/scid/IL2rgKO Mice.

Establishment of Novel Disease Models for Human Acute Type ATL and HTLV-I Carrier Using NOD-scid/IL2rg null Mouse.

Human AML Stem Cells Remain Quiescent and Exhibit Chemotherapy Resistance within the Bone Marrow Endosteal Region.

Highly Purified Hematopoietic Stem Cell Can Generate Cardiomyocytes Via Myeloid Progenitors through Cell Fusion.

Expression of CD10 and CD7 Defines Distinct In Vivo Lymphoid Reconstituting Capacity within Human Cord Blood CD34+CD38-Cells.

Xenotransplantation of Primary CD34+CD38- Hematopoietic Stem Cells Results in an In Vivo Model of Idiopathic Myelofibrosis.

Human Conventional and Plasmacytoid Dendritic Cells Can Originate from Both Lymphoid and Myeloid Progenitors in a New Humanized Mouse System.

Long-Term Engraftment and Self-Renewal of AML Stem Cells in the Newborn NOD-scid/IL2rgnull Immunodeficient Mouse Model.

In Vivo Generation and the Mechanism of Bone Marrow- and Cord Blood-Derived Cardiomyocytes.

Neonatal NOD/SCID/IL2rg-Null Mice Support the Functional Development of Human Hematopoietic and Immune Systems.

Human CB-Derived Cells Give Rise to Insulin-Producing-Cells in Xenogeneic Hosts.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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