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Franco Izzo, PhD
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Journal Articles

Single-Cell Multi-Omics in Human Clonal Hematopoiesis Reveals That DNMT3A R882 Mutations Perturb Early Progenitor States through Selective Hypomethylation

Anna S Nam, MD, Neville Dusaj, MS, Franco Izzo, PhD, Rekha Murali, MS, Tarek H Mouhieddine, MD, Robert M Myers, Jesus Sotelo, Salima Benbarche, PhD, Federico Gaiti, PhD, Sabrin Tahri, MD MSc, Omar Abdel-Wahab, MD, Irene M. Ghobrial, MD, Ronan Chaligne, PhD, Dan A. Landau, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 1–2.
https://doi.org/10.1182/blood-2020-142574
Published: 2020
Journal Articles

Single-Cell Multi-Omics Reveals Distinct Paths to Survival of Admixed BTK C481 Mutant Vs. Wild-Type Cells in Clinically Progressing Chronic Lymphocytic Leukemia

Andrew Lipsky, MD, Danny Luan, MPH, Shirley Chen, BSc, Ronan Chaligne, PhD, Neville Dusaj, MS, Erica B Bhavsar, BS, Chelston Ang, MS, Anna S Nam, MD, Federico Gaiti, PhD, Paulina Chamely, MSc, Nathaniel D. Omans, MS, Preeti Trisal, MS, Anita K Gandhi, PhD, Kyu-Tae Kim, PhD, Rafael Schulman, BS, Joshua S. Schiffman, PhD, Franco Izzo, PhD, Gregory Mullokandov, MD PhD, Chingiz Underbayev, MD PhD, Adrian Wiestner, MD PhD, John N. Allan, MD, Richard R. Furman, MD, Dan A. Landau, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 40–42.
https://doi.org/10.1182/blood-2020-138374
Published: 2020
Journal Articles

m 6 A Maintains Hematopoietic Stem and Progenitor Cell Identity

Yuanming Cheng, PhD, Hanzhi Luo, PhD, Franco Izzo, PhD, Brian F Pickering, PhD, Ly P Vu, PhD, Alexandra Schurer, BS, Saroj Gourkanti, BA, Samie R. Jaffrey, MD PhD, Dan A. Landau, MD PhD, Michael G. Kharas, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 327.
https://doi.org/10.1182/blood-2018-99-117191
Published: 2018
Journal Articles

High Throughput Droplet Single-Cell Genotyping of Transcriptomes (GoT) Reveals the Cell Identity Dependency of the Transcriptional Output of Somatic Mutations

Anna S Nam, MD, Kyu-Tae Kim, PhD, Ronan Chaligne, PhD, Franco Izzo, PhD, Chelston Ang, MS, Nathaniel Omans, MS, Alessandro Pastore, Justin Taylor, MD, Alicia Alonso, Wayne Tam, MD PhD, Ronald Hoffman, MD, Joseph Scandura, MDPhD, Raul Rabadan, PhD, Omar I Abdel-Wahab, MD, Peter Smibert, PhD, Dan A. Landau, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 541.
https://doi.org/10.1182/blood-2018-99-119236
Published: 2018
Journal Articles

Multimodal Single-Cell Profiling Defines the Epigenetic Determinants of Chronic Lymphocytic Leukemia Evolution

Ronan Chaligne, PhD, Federico Gaiti, PhD, Franco Izzo, PhD, Steven Kothen-Hill, MS, Hongcang Gu, Kevin Huang, BS, Davide Risso, PhD, Rafael Schulman, BS, Ryan M Brand, Stanley C Lee, PhD, Asaf Poran, Kye-Tae Kim, PhD, Alessandro Pastore, Alicia Alonso, Andreas Gnirke, Catherine J. Wu, MD, Omar I Abdel-Wahab, MD, Alexander Meissner, PhD, Dan A. Landau, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1312.
https://doi.org/10.1182/blood-2018-99-115596
Published: 2018
Journal Articles

A Novel iPSC Model Reveals a Role for RUNX1 in the Maintenance of AML Leukemia Stem Cells

Josephine Wesely, PhD MSc, BSc, Andriana G. Kotini, PhD, Maria Georgomanoli, PhD, Hanzhi Luo, PhD, Han Yuan, Franco Izzo, PhD, Dan A. Landau, MD PhD, Christina Leslie, PhD, Michael G. Kharas, PhD, Eirini P. Papapetrou, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 772.
https://doi.org/10.1182/blood-2018-99-111506
Published: 2018
Journal Articles

Single-Cell Methylome and Transcriptome High-Resolution Maps Define the Effects of Epigenetic Modifiers on the Landscape of Hematopoietic Differentiation

Franco Izzo, PhD, Asaf Poran, Stanley Chun-Wei Lee, PhD, Ronan Chaligne, PhD, Federico Gaiti, PhD, Steven Kothen-Hill, MS, Rafael Schulman, BS, Michelle Ki, Kenigsberg Ephraim, PhD, Omar Abdel-Wahab, MD, Dan A. Landau, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 559.
https://doi.org/10.1182/blood.V130.Suppl_1.559.559
Published: 2017