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Francis Y. Lee, Ph.D.
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Journal Articles

Pharmacokinetics- and Pharmacodynamics-Guided Optimization of the Dose and Treatment Schedule for the Dual SRC/ABL Inhibitor BMS-354825.

Feng Roger Luo, Ph.D., Zheng Yang, Ph.D., Amy Camuso, B.S., Richard Smykla, B.S., Stephen Castenada, B.S., Christine Flefleh, B.S., Krista Fager, M.S., Ivan Inigo, B.S., David Kan, B.S., Kelly McGlinchey, B.S., Mei-Li Wen, M.S., Robert Wild, Ph.D., Robert Borzilleri, Ph.D., Louis Lombardo, Ph.D., Robert Kramer, Ph.D., Francis Y. Lee, Ph.D.
Journal: Blood
Blood (2004) 104 (11): 1987.
https://doi.org/10.1182/blood.V104.11.1987.1987
Published: 2004
Journal Articles

BMS-354825, a Dual SRC/ABL Kinase Inhibitor, Displays Potent Anti-Tumor Activity in a Model of Intracranial CML Growth.

Robert Wild, Ph.D., Stephen Castaneda, B.S., Christine Flefleh, B.S., Krista Fager, B.S., Ivan Inigo, B.S., David Kan, B.S., Richard Smykla, B.S., Amy Camuso, B.S., Kelly McGlinchey, B.S., Mei-Li Wen, B.S., Feng Roger Luo, Ph.D., Robert Borzilleri, Ph.D., Louis Lombardo, Ph.D., Robert Kramer, Ph.D., Francis Y. Lee, Ph.D.
Journal: Blood
Blood (2004) 104 (11): 1988.
https://doi.org/10.1182/blood.V104.11.1988.1988
Published: 2004
Journal Articles

BMS-354825 Potently Inhibits the Kinase Activity of KIT Activation Loop Mutations Associated with Systemic Mastocytosis and Induces Apoptosis of Mastocytosis Cell Lines.

Marcus Schittenhelm, M.D., Sharon Shiraga, Francis Y. Lee, Ph.D., Michael C. Heinrich, M.D.
Journal: Blood
Blood (2004) 104 (11): 2424.
https://doi.org/10.1182/blood.V104.11.2424.2424
Published: 2004
Journal Articles

The Crystal Structure of Abl Kinase with BMS-354825, a Dual SRC/ABL Kinase Inhibitor.

John S. Tokarski, Ph.D., John Newitt, Ph.D., Francis Y. Lee, Ph.D., Louis Lombardo, Ph.D., Robert Borzilleri, Ph.D., Kevin Kish, Dianlin Xie, Yaqun Zhang, Janet D. Cheng, Ph.D., Susan E. Kiefer, Chieh Ying J. Chang, Herbert E. Klei, Ph.D.
Journal: Blood
Blood (2004) 104 (11): 553.
https://doi.org/10.1182/blood.V104.11.553.553
Published: 2004