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Journal Articles

The Infection-Driven Production/Secretion of Inflammatory Cytokines By Circulating Monocytes of Myelofibrosis Is Defective and Is Reactivated after In Vivo JAK1/2 Inhibition

Martina Barone, PhD, Francesca Ricci, BS, Marco Romano, PhD, Dorian Forte, PhD, Giuseppe Auteri, MD, Francesco Fabbri, PhD, Emanuela Ottaviani, Pierluigi Tazzari, MD, Nicola Vianelli, MD, Giovanni Martinelli, MD, Michele Cavo, Francesca Palandri, PhD MD, Lucia Catani

Blood (2019) 134 (Supplement_1): 1686.

https://doi.org/10.1182/blood-2019-127322

Published: 2019

Journal Articles

Molecular Profiling Of Blastic Plasmacytoid Dendritic CELL Neoplasm Reveals A Unique Pattern and Suggests Selective Sensitivity To NF-KB Pathway Inhibition

Blood (2013) 122 (21): 2502.

https://doi.org/10.1182/blood.V122.21.2502.2502

Published: 2013

Journal Articles

Temsirolimus, An Allosteric mTORC1 Inhibitor, Is Synergistic with Clofarabine in AML and AML Leukemia Initiating Cells

Francesca Chiarini, PhD, Cecilia Grimaldi, BS, Francesca Ricci, BS, Pierluigi Tazzari, MD, Ilaria Iacobucci, PhD, Giovanni Martinelli, MD, Pasqualepaolo Pagliaro, MD, James McCubrey, Sergio Amadori, MD, Alberto M Martelli, MD

Blood (2011) 118 (21): 2596.

https://doi.org/10.1182/blood.V118.21.2596.2596

Published: 2011

Journal Articles

Targeted Inhibition of mTORC1 and mTORC2 by the Active-Site mTOR Inhibitors, PP-242 and OSI-027, Has Cytotoxic Effects In T-Cell Acute Lymphoblastic Leukemia

Camilla Evangelisti, PhD, Francesca Chiarini, PhD, Francesca Ricci, BS, Pierluigi Tazzari, MD, Andrea Pession, MD, PhD, James A McCubrey, PhD, Alberto M. Martelli, MD

Blood (2010) 116 (21): 3242.

https://doi.org/10.1182/blood.V116.21.3242.3242

Published: 2010

Journal Articles

AMP-Dependent Kinase/mTOR Complex 1 Signaling In T-Cell Acute Lymphoblastic Leukemia: Therapeutical Implications

Cecilia Grimaldi, BS, Francesca Chiarini, PhD, Francesca Ricci, BS, Pierluigi Tazzari, MD, Michela Battistelli, PhD, Elisabetta Falcieri, MD, Andrea Pession, MD, PhD, James McCubrey, PhD, Alberto M. Martelli, MD

Blood (2010) 116 (21): 3225.

https://doi.org/10.1182/blood.V116.21.3225.3225

Published: 2010

Journal Articles

The CD47 Pathway Is Deregulated In Human Immune Thrombocytopenia (ITP).

Lucia Catani, BS, Daria Sollazzo, BS, Francesca Ricci, BS, Francesca Palandri, Nicola Polverelli, MD, Michele Baccarani, Nicola Vianelli, MD, Roberto M. Lemoli, MD

Blood (2010) 116 (21): 3776.

https://doi.org/10.1182/blood.V116.21.3776.3776

Published: 2010

Journal Articles

PDGFRA Activity Is Mediated by An Autocrine Loop in Peripheral T-Cell Lymphoma/Not Otherwise Specified (PTCL/NOS).

Maura Rossi, Francesco Alviano, Antonella Laginestra, Pierluigi Tazzari, MD, Francesca Ricci, BS, Aurora Esposito, Claudio Agostinelli, Maria Teresa Sista, Anna Gazzola, Claudia Mannu, Simona Righi, Maria Rosaria Sapienza, Gian Paolo Bagnara, Sylvia Hartmann, Martin Leo Hansmann, Pier Luigi Zinzani, Stefano Aldo Pileri, Pier Paolo Piccaluga

Blood (2009) 114 (22): 4631.

https://doi.org/10.1182/blood.V114.22.4631.4631

Published: 2009

Journal Articles

Dual Inhibition of Phosphatidylinositol 3-Kinase and Mammalian Target of Rapamycin with NVP-BEZ235 as a New Therapeutic Option for T-Cell Acute Lymphoblastic Leukemia.

Francesca Chiarini, BS, Cecilia Grimaldi, BS, Francesca Ricci, BS, Pierluigi Tazzari, MD, Camilla Evangelisti, PhD, Andrea Pession, MD, PhD, Pasqualepaolo Pagliaro, MD, James McCubrey, PhD, Alberto M. Martelli, MD

Blood (2009) 114 (22): 2025.

https://doi.org/10.1182/blood.V114.22.2025.2025

Published: 2009

Journal Articles

Aberrant PDGFRA Signalling Is Sustained by An Autocrine Loop in Peripheral T-Cell Lymphoma Not Otherwise Specified

Pier Paolo Piccaluga, Maura Rossi, Aurora Esposito, PierLuigi Tazzari, MD, Francesca Ricci, BS, Claudio Agostinelli, Simona Righi, Anna Gazzola, Philip Went, Francesco Alviano, Gian Paolo Bagnara, P.L. Zinzani, M.D., Stefano A. Pileri

Blood (2008) 112 (11): 5331.

https://doi.org/10.1182/blood.V112.11.5331.5331

Published: 2008

Journal Articles

Erucylphosphohomocholine, the First Intravenously Applicable Alkylphosphocholine, Induces Cell Cycle Arrest, Apoptosis, and Synergizes with Chemotherapeutic Drugs in Acute Myelogenous Leukemia Cells-a Novel Therapeutic Approach for Leukemia.

Veronica Papa, BS, PierLuigi Tazzari, MD, Francesca Chiarini, BS, Francesca Ricci, BS, Giovanni Martinelli, MD, Andrea Bontadini, MD, James McCubrey, PhD, Lars H Lindner, MD, Hansjoerg Eibl, PhD, Alberto M. Martelli, MD

Blood (2008) 112 (11): 1330.

https://doi.org/10.1182/blood.V112.11.1330.1330

Published: 2008

Journal Articles

PI-103, a Dual Inhibitor of Class IA Phosphatidylinositol 3-Kinase and Mammalian Target of Rapamycin, Has Cytotoxic Activity in T-Cell Acute Lymphoblastic Leukemia Cells: A New Therapeutic Strategy in T-Cell Acute Lymphoblastic Leukemia.

Francesca Chiarini, BS, Federica Fala, PhD, Francesca Ricci, BS, PierLuigi Tazzari, MD, Annalisa Astolfi, PhD, Andrea Pession, MD, PhD, James McCubrey, PhD, Alberto M. Martelli, MD

Blood (2008) 112 (11): 1921.

https://doi.org/10.1182/blood.V112.11.1921.1921

Published: 2008

Journal Articles

Synergistic Proapoptotic Activity of Recombinant TRAIL Plus the Akt Inhibitor Perifosine in Acute Myelogenous Leukemia Cells-a Novel Therapeutic Approach for Leukemia Displaying Elevated Akt Signaling.

PierLuigi Tazzari, MD, Veronica Papa, BS, Francesca Ricci, BS, Francesca Chiarini, BS, Camilla Evangelisti, PhD, Giovanni Martinelli, MD, Andrea Bontadini, MD, James McCubrey, PhD, Alberto M. Martelli, MD

Blood (2008) 112 (11): 957.

https://doi.org/10.1182/blood.V112.11.957.957

Published: 2008

Journal Articles

The Novel Akt Inhibitor Perifosine Induces Apoptosis, Cell Cycle Arrest and Synergizes with Chemotherapeutic Drugs in Acute Myelogenous Leukemia Cells by a JNK Dependent Mechanism - A Novel Therapeutic Approach for Leukemia Displaying Elevated Akt Signaling.

Alberto M. Martelli, MD, PhD, Veronica Papa, BS, Pier Luigi Tazzari, MD, Francesca Chiarini, BS, Alessandra Cappellini, PhD, Francesca Ricci, BS, Anna Maria Billi, PhD, Camilla Evangelisti, PhD, Steve L. Abrams, BS, Emanuela Ottaviani, PhD, Giovanni Martinelli, MD, James A. McCubrey, PhD

Blood (2007) 110 (11): 3355.

https://doi.org/10.1182/blood.V110.11.3355.3355

Published: 2007

NARROW

The Infection-Driven Production/Secretion of Inflammatory Cytokines By Circulating Monocytes of Myelofibrosis Is Defective and Is Reactivated after In Vivo JAK1/2 Inhibition

Molecular Profiling Of Blastic Plasmacytoid Dendritic CELL Neoplasm Reveals A Unique Pattern and Suggests Selective Sensitivity To NF-KB Pathway Inhibition

Temsirolimus, An Allosteric mTORC1 Inhibitor, Is Synergistic with Clofarabine in AML and AML Leukemia Initiating Cells

Targeted Inhibition of mTORC1 and mTORC2 by the Active-Site mTOR Inhibitors, PP-242 and OSI-027, Has Cytotoxic Effects In T-Cell Acute Lymphoblastic Leukemia

AMP-Dependent Kinase/mTOR Complex 1 Signaling In T-Cell Acute Lymphoblastic Leukemia: Therapeutical Implications

The CD47 Pathway Is Deregulated In Human Immune Thrombocytopenia (ITP).

PDGFRA Activity Is Mediated by An Autocrine Loop in Peripheral T-Cell Lymphoma/Not Otherwise Specified (PTCL/NOS).

Dual Inhibition of Phosphatidylinositol 3-Kinase and Mammalian Target of Rapamycin with NVP-BEZ235 as a New Therapeutic Option for T-Cell Acute Lymphoblastic Leukemia.

Aberrant PDGFRA Signalling Is Sustained by An Autocrine Loop in Peripheral T-Cell Lymphoma Not Otherwise Specified

Erucylphosphohomocholine, the First Intravenously Applicable Alkylphosphocholine, Induces Cell Cycle Arrest, Apoptosis, and Synergizes with Chemotherapeutic Drugs in Acute Myelogenous Leukemia Cells-a Novel Therapeutic Approach for Leukemia.

PI-103, a Dual Inhibitor of Class IA Phosphatidylinositol 3-Kinase and Mammalian Target of Rapamycin, Has Cytotoxic Activity in T-Cell Acute Lymphoblastic Leukemia Cells: A New Therapeutic Strategy in T-Cell Acute Lymphoblastic Leukemia.

Synergistic Proapoptotic Activity of Recombinant TRAIL Plus the Akt Inhibitor Perifosine in Acute Myelogenous Leukemia Cells-a Novel Therapeutic Approach for Leukemia Displaying Elevated Akt Signaling.

The Novel Akt Inhibitor Perifosine Induces Apoptosis, Cell Cycle Arrest and Synergizes with Chemotherapeutic Drugs in Acute Myelogenous Leukemia Cells by a JNK Dependent Mechanism - A Novel Therapeutic Approach for Leukemia Displaying Elevated Akt Signaling.

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American Society of Hematology

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American Society of Hematology

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