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Journal Articles

A Phase 1 Single Dose Escalation Study of Palifermin Administered Pre-Transplant Conditioning in Subjects Undergoing Matched Unrelated Donor Allogeneic Hematopoietic Stem Cell Transplantation

Alen Ostojic, MD, Noa G. Holtzman, MD, Lauren M. Curtis, MD, Brian C. Shaffer, MD, Jeffrey S Rubin, MD PhD, Frances T. Hakim, PhD, Jacqueline W Mays, DDS, PhD, Theo Heller, MD, Edward W Cowen, MD, Sabine Werner, PhD, Michael Emanuel, BSN, RN, Seth M. Steinberg, PhD, Ronald E. Gress, MD, Steven Z. Pavletic, MD MS

Blood (2020) 136 (Supplement 1): 21.

https://doi.org/10.1182/blood-2020-140059

Published: 2020

Journal Articles

Phase 1 Study of Alvelestat, an Oral Neutrophil Elastase Inhibitor, in Patients with Bronchiolitis Obliterans Syndrome after Hematopoietic Cell Transplantation

Annie Im, MD, Noa G. Holtzman, MD, Lauren M. Curtis, MD, Laura Parsons-Wandell, RN, Jeannette Nashed, BSN MSN CRNP, Cody Peer, PhD, William D. Figg, PhD, Amisha Barochia, MBBS, MHS, Jeremy J. Rose, MS, Frances T. Hakim, PhD, Steven Z. Pavletic, MD MS

Blood (2020) 136 (Supplement 1): 18–19.

https://doi.org/10.1182/blood-2020-140481

Published: 2020

Journal Articles

Efficacy and Safety of Baricitinib in Refractory Chronic Graft-Versus-Host Disease (cGVHD): Preliminary Analysis Results of a Phase 1/2 Study

Noa G. Holtzman, MD, Annie Im, MD, Alen Ostojic, MD, Lauren M. Curtis, MD, Laura Parsons-Wandell, RN, Jeannette Nashed, BSN MSN CRNP, Cody Peer, PhD, William D. Figg, Sr., PharmD, M. Teresa Magone, MD, Edward W Cowen, MD, Jacqueline W Mays, DDS, PhD, Frances T. Hakim, PhD, Jeremy J. Rose, MS, Marie C Pouzelles, PhD, Naomi Taylor, MD PhD, Steven Z. Pavletic, MD MS

Blood (2020) 136 (Supplement 1): 1.

https://doi.org/10.1182/blood-2020-140392

Published: 2020

Journal Articles

Single-Cell RNA-Seq Identifies Potentially Pathogenic B Cell Populations That Uniquely Circulate in Patients with Chronic Gvhd

Jonathan C Poe, PhD, Dadong Zhang, PhD, Jichun Xie, PhD, Rachel A. DiCioccio, BS, Xiaodi Qin, MS, Jiyuan Fang, MS, Vincent T. Ho, MD, Jeremy J. Rose, MS, Steven Z. Pavletic, MD MS, Frances T. Hakim, PhD, Wei Jia, MD PhD, Amy N. Suthers, PhD, Mitchell E. Horwitz, MD, David A. Rizzieri, MD, William C. McManigle, MD, Nelson J. Chao, MD, Kouros Owzar, PhD, Stefanie Sarantopoulos, MD PhD

Blood (2019) 134 (Supplement_1): 874.

https://doi.org/10.1182/blood-2019-130928

Published: 2019

Journal Articles

Clinical Characterization and Cytokine Profile of Fatigue in Patients with Chronic Gvhd

Sencer Goklemez, MD, Saligan Leorey, PhD, Filip Pirsl, Seth M. Steinberg, PhD, Sandra A Mitchell, PhD, Frances T. Hakim, PhD, Jeremy J. Rose, MS, Zhigang Kang, MD, Yunkai Yu, Liang Cao, Annie Im, MD, Steven Z. Pavletic, MD MS

Blood (2019) 134 (Supplement_1): 3282.

https://doi.org/10.1182/blood-2019-124055

Published: 2019

Journal Articles

Accelerated T Cell Senescence after Allogeneic Hematopoeitic Stem Cell Transplantation

Sean C. Dougherty, Veena Kapoor, Andrew J Uhlman, B.S., Sarfraz Memon, MD, Monica Cho, Jeremy Rose, PhD, Gregory A. Swan, B.S., Frances T. Hakim, PhD, Ronald E. Gress, MD

Blood (2017) 130 (Supplement 1): 4523.

https://doi.org/10.1182/blood.V130.Suppl_1.4523.4523

Published: 2017

Journal Articles

Increased TLR7 Signaling of BCR-Activated B Cells in Chronic Graft-Versus Host Disease (cGVHD)

Amy N. Suthers, PhD, Hsuan Su, MS, Sarah M. Anand, MD, Jonathan C Poe, PhD, Jeremy J. Rose, MS, Frances T. Hakim, PhD, Steven Z. Pavletic, MD, David A. Rizzieri, MD, Mitchell E. Horwitz, MD, Yiping Yang, MD PhD, Nelson J. Chao, MDM.B.A, Stefanie Sarantopoulos, MD PhD

Blood (2017) 130 (Supplement 1): 75.

https://doi.org/10.1182/blood.V130.Suppl_1.75.75

Published: 2017

Journal Articles

All- Trans Retinoic Acid (ATRA) Targets IRF4 Deficient, NOTCH2-Activated B Cells from Chronic Gvhd Patients

Jonathan C. Poe, PhD, Wei Jia, MD, Hsuan Su, MS, Zhiguo Li, PhD, Frances T. Hakim, PhD, Steven Z. Pavletic, MD, Jeremy J. Rose, MS, David A Rizzieri, MD, Yiping Yang, MD PhD, Benny J. Chen, MD, Sarah Anand, MD, Jerome Ritz, MD, Christian W. Siebel, PhD, Nelson J. Chao, MD, Ivan Maillard, MD PhD, Stefanie Sarantopoulos, MD PhD

Blood (2016) 128 (22): 669.

https://doi.org/10.1182/blood.V128.22.669.669

Published: 2016

Journal Articles

Pilot Study of Radiation-Targeted Donor Lymphocyte Infusion for Cancer Progression after Allogeneic Hematopoietic Stem Cell Transplantation

Nancy M. Hardy, MD, Deborah Citrin, MD, Frances T. Hakim, PhD, Daniele N. Avila, CRNP, Bazetta Blacklock-Schuver, RN, Stephanie Cotton, RN, Monica Cho, Daniel H. Fowler, MD, Juan C. Gea-Banacloche, MD, Noa G. Holtzman, MD, Karen A. Kurdziel, MD, Sarfraz Memon, MD, Steven Z. Pavletic, MD, Stefania Pittaluga, MD PhD, Jeremy J. Rose, BA, Claude Sportes, MD, Jennifer S. Wilder, RN, Ronald E. Gress, MD, Michael R. Bishop, MD

Blood (2015) 126 (23): 1962.

https://doi.org/10.1182/blood.V126.23.1962.1962

Published: 2015

Journal Articles

Clinical and Immunologic Characteristics of Patients with Chronic Graft-Versus-Host Disease Persisting Seven or More Years after Diagnosis

Annie Im, MD, Frances T. Hakim, PhD, Filip Pirsl, Seth M. Steinberg, PhD, Lauren M. Curtis, MD, Sandra A. Mitchell, CRNP, PhD AOCN, Edward W. Cowen, MD MHSc, Jennifer Hsu, RN, Judy Baruffaldi, Licia Masuch, Juan C. Gea-Banacloche, MD, David C. Halverson, MD, Daniel H. Fowler, MD, Ronald E. Gress, MD, Steven Z. Pavletic, MD

Blood (2015) 126 (23): 1937.

https://doi.org/10.1182/blood.V126.23.1937.1937

Published: 2015

Journal Articles

Remissions of Multiple Myeloma during a First-in-Humans Clinical Trial of T Cells Expressing an Anti-B-Cell Maturation Antigen Chimeric Antigen Receptor

Syed Abbas Ali, MD, Victoria Shi, Michael Wang, MD, David Stroncek, MD, Irina Maric, Jennifer N Brudno, MD, Maryalice Stetler-Stevenson, Jeremy J. Rose, BA, Steven Feldman, Brenna Hansen, Frances T. Hakim, PhD, Ronald E. Gress, MD, James N. Kochenderfer, MD

Blood (2015) 126 (23): LBA-1.

https://doi.org/10.1182/blood.V126.23.LBA-1.LBA-1

Published: 2015

Journal Articles

Alemtuzumab-Cyclosporine Versus Tacrolimus-Methotrexate-Sirolimus for Graft-Versus-Host Disease Prophylaxis in Reduced Intensity Allogeneic Hematopoietic Stem Cell Transplantation from Unrelated Donors: Final Results of a Randomized Trial

Blood (2015) 126 (23): 65.

https://doi.org/10.1182/blood.V126.23.65.65

Published: 2015

Journal Articles

Upregulation of Interferon-Inducible and Damage Response Receptors in Chronic Graft-Versus-Host Disease

Frances T. Hakim, PhD, Sarfraz Memon, MD, Ping Jin, PhD, Matin M. Imanguli, DDS, MD, Najibah Rehman, MD, Xiao-Yi Yan, MS, Jeremy J. Rose, BA, Jacqueline W. Mays, DDS, PhD, Susan Dhamala, BA, Veena Kapoor, William Telford, PhD, David C. Halverson, MD, Kristin Baird, MD, Daniel H. Fowler, MD, David Stroncek, MD, Edward W. Cowen, MD MHSc, Steven Z. Pavletic, MD, Ronald E. Gress, MD

Blood (2015) 126 (23): 922.

https://doi.org/10.1182/blood.V126.23.922.922

Published: 2015

Journal Articles

Targeting the Human Notch 2-BCR Axis: A Driver of B-Cell Hyper-Responsiveness in Active Chronic Graft-Versus Host Disease (cGVHD)

Jonathan C. Poe, PhD, Wei Jia, MD, Zhiguo Li, PhD, Frances T. Hakim, PhD, Steven Z. Pavletic, MD, Jeremy J. Rose, BA, David A. Rizzieri, MD, Yiping Yang, MD PhD, Benny J. Chen, MD, Michael Green, MD, Sarah Anand, MD, Christian W. Siebel, PhD, Ivan Maillard, MD PhD, Nelson J. Chao, MD, Stefanie Sarantopoulos, MD PhD

Blood (2015) 126 (23): 145.

https://doi.org/10.1182/blood.V126.23.145.145

Published: 2015

Journal Articles

FLT Imaging Reveals Kinetics and Biology of Engraftment after Myeloablative HSCT

Blood (2014) 124 (21): 1147.

https://doi.org/10.1182/blood.V124.21.1147.1147

Published: 2014

Journal Articles

Donor-Derived Anti-CD19 Chimeric-Antigen-Receptor-Expressing T Cells Cause Regression Of Malignancy Persisting After Allogeneic Hematopoietic Stem Cell Transplantation

Blood (2013) 122 (21): 151.

https://doi.org/10.1182/blood.V122.21.151.151

Published: 2013

Journal Articles

B Cell Deficiency and CD21low B Cells As Markers For Measuring Cgvhd Severity and Activity In a Large Patient Cohort

Zoya Kuzmina, MD, Jeremy Rose, Najibah Rehman, Edward W. Cowen, MD, Kristin Baird, MD, Kristen Cole, RN, Judy Baruffaldi, Ronald E. Gress, MD, Steven Z. Pavletic, MD, Frances T. Hakim, PhD

Blood (2013) 122 (21): 4623.

https://doi.org/10.1182/blood.V122.21.4623.4623

Published: 2013

Journal Articles

Infectious Complications After Unrelated Donor Allogeneic Hematopoietic Cell Transplantation With Or Without Alemtuzumab Based In Vivo Lymphocyte Depletion

Brian C. Shaffer, MD, Andrew Flynn, David Moorshead, Zach Powell, Jennifer Hsu, RN, Rachel B Salit, MD, Frances T. Hakim, PhD, Ronald E. Gress, MD, Michael Bishop, MD, Juan Gea-Banacloche, MD, Steven Z. Pavletic, MD

Blood (2013) 122 (21): 4580.

https://doi.org/10.1182/blood.V122.21.4580.4580

Published: 2013

Journal Articles

Influence of Graft Versus-Host Disease Prophylaxis Regimen On T-Cell Repertoire Diversity Following Reduced-Intensity HLA-Matched Unrelated Donor Allogeneic Hematopoietic Stem Cell Transplantation.

Rachel B. Salit, MD, Frances T. Hakim, PhD, Michael R. Bishop, MD, Thea M. Friedman, PhD, Robert Korngold, PhD, Kira Goldgirsh, PhD, Sarfraz Memon, MD, Seth M. Steinberg, PhD, David Liewehr, MS, Daniel Peaceman, BS, Jennifer Wilder, RN, Kelly Bryant, RN, Daniel H. Fowler, MD, Juan Gea-Banacloche, MD, Ronald E. Gress, MD, Steven Z. Pavletic, MD

Blood (2012) 120 (21): 3054.

https://doi.org/10.1182/blood.V120.21.3054.3054

Published: 2012

Journal Articles

Pre-Emptive T-Rapa Cell DLI for Therapy of High-Risk Lymphoma After Low-Intensity Allogeneic HCT

Blood (2012) 120 (21): 471.

https://doi.org/10.1182/blood.V120.21.471.471

Published: 2012

NARROW

A Phase 1 Single Dose Escalation Study of Palifermin Administered Pre-Transplant Conditioning in Subjects Undergoing Matched Unrelated Donor Allogeneic Hematopoietic Stem Cell Transplantation

Phase 1 Study of Alvelestat, an Oral Neutrophil Elastase Inhibitor, in Patients with Bronchiolitis Obliterans Syndrome after Hematopoietic Cell Transplantation

Efficacy and Safety of Baricitinib in Refractory Chronic Graft-Versus-Host Disease (cGVHD): Preliminary Analysis Results of a Phase 1/2 Study

Single-Cell RNA-Seq Identifies Potentially Pathogenic B Cell Populations That Uniquely Circulate in Patients with Chronic Gvhd

Clinical Characterization and Cytokine Profile of Fatigue in Patients with Chronic Gvhd

Accelerated T Cell Senescence after Allogeneic Hematopoeitic Stem Cell Transplantation

Increased TLR7 Signaling of BCR-Activated B Cells in Chronic Graft-Versus Host Disease (cGVHD)

All- Trans Retinoic Acid (ATRA) Targets IRF4 Deficient, NOTCH2-Activated B Cells from Chronic Gvhd Patients

Pilot Study of Radiation-Targeted Donor Lymphocyte Infusion for Cancer Progression after Allogeneic Hematopoietic Stem Cell Transplantation

Clinical and Immunologic Characteristics of Patients with Chronic Graft-Versus-Host Disease Persisting Seven or More Years after Diagnosis

Remissions of Multiple Myeloma during a First-in-Humans Clinical Trial of T Cells Expressing an Anti-B-Cell Maturation Antigen Chimeric Antigen Receptor

Alemtuzumab-Cyclosporine Versus Tacrolimus-Methotrexate-Sirolimus for Graft-Versus-Host Disease Prophylaxis in Reduced Intensity Allogeneic Hematopoietic Stem Cell Transplantation from Unrelated Donors: Final Results of a Randomized Trial

Upregulation of Interferon-Inducible and Damage Response Receptors in Chronic Graft-Versus-Host Disease

Targeting the Human Notch 2-BCR Axis: A Driver of B-Cell Hyper-Responsiveness in Active Chronic Graft-Versus Host Disease (cGVHD)

FLT Imaging Reveals Kinetics and Biology of Engraftment after Myeloablative HSCT

Donor-Derived Anti-CD19 Chimeric-Antigen-Receptor-Expressing T Cells Cause Regression Of Malignancy Persisting After Allogeneic Hematopoietic Stem Cell Transplantation

B Cell Deficiency and CD21low B Cells As Markers For Measuring Cgvhd Severity and Activity In a Large Patient Cohort

Infectious Complications After Unrelated Donor Allogeneic Hematopoietic Cell Transplantation With Or Without Alemtuzumab Based In Vivo Lymphocyte Depletion

Influence of Graft Versus-Host Disease Prophylaxis Regimen On T-Cell Repertoire Diversity Following Reduced-Intensity HLA-Matched Unrelated Donor Allogeneic Hematopoietic Stem Cell Transplantation.

Pre-Emptive T-Rapa Cell DLI for Therapy of High-Risk Lymphoma After Low-Intensity Allogeneic HCT

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American Society of Hematology

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American Society of Hematology

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