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Elenoe C Smith, PhD
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Journal Articles

Crispr-Cas9 Saturating Mutagenesis Reveals an Achilles Heel in the BCL11A Erythroid Enhancer for Fetal Hemoglobin Induction (by Genome Editing)

Daniel E. Bauer, MD, PhD, Matthew C. Canver, B.S., Elenoe C. Smith, PhD, Falak Sher, PhD, Luca Pinello, PhD, Neville E. Sanjana, PhD, Ophir Shalem, PhD, Diane D. Chen, B.S., Patrick G. Schupp, B.S., Divya S. Vinjamur, PhD, Sara P. Garcia, PhD, Sidinh Luc, PhD, Ryo Kurita, PhD, Yukio Nakamura, MD, PhD, Yuko Fujiwara, PhD, Takahiro Maeda, MD, PhD, Guo-Cheng Yuan, PhD, Guillaume Lettre, PhD, Feng Zhang, PhD, Stuart H. Orkin, MD
Journal: Blood
Blood (2015) 126 (23): 638.
https://doi.org/10.1182/blood.V126.23.638.638
Published: 2015
Journal Articles

Fine-Mapping and Genome Editing Reveal An Essential Erythroid Enhancer At The HbF-Associated BCL11A Locus

Daniel E. Bauer, MD, PHD, Sophia C. Kamran, MD, Samuel Lessard, BS, Jian Xu, PhD, Yuko Fujiwara, PhD, Carrie Lin, BS, Zhen Shao, PhD, Matthew C. Canver, BS, Elenoe C. Smith, PhD, Luca Pinello, PhD, Peter J. Sabo, PhD, Jeff Vierstra, BS, Richard A. Voit, BS, Guo-Cheng Yuan, PhD, Matthew H. Porteus, MD, PhD, John Stamatoyannopoulos, MD, Guillaume Lettre, PhD, Stuart H. Orkin, MD
Journal: Blood
Blood (2013) 122 (21): 437.
https://doi.org/10.1182/blood.V122.21.437.437
Published: 2013
Journal Articles

Identification Of BCL11A Structure-Function Domains For Fetal Hemoglobin Silencing

Jian Xu, PHD, Daniel E. Bauer, MD, PhD, Cong Peng, PhD, Elenoe C. Smith, PhD, Stuart H. Orkin, MD
Journal: Blood
Blood (2013) 122 (21): 435.
https://doi.org/10.1182/blood.V122.21.435.435
Published: 2013
Journal Articles

Induction of Megakaryocyte Differentiation Drives Nuclear Accumulation and Transcriptional Function of MKL1 Via Actin Polymerization and RhoA Activation

Elenoe C Smith, PhD, Alexandra M Teixeira, Rachel C Chen, Lin Wang, Yuan Gao, PhD, Katherine Hahn, PhD, Diane S Krause, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 3440.
https://doi.org/10.1182/blood.V120.21.3440.3440
Published: 2012