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Journal Articles

Two BMP responsive elements, STAT, and bZIP/HNF4/COUP motifs of the hepcidin promoter are critical for BMP, SMAD1, and HJV responsiveness

Jaroslav Truksa, Pauline Lee, Ernest Beutler

Blood (2009) 113 (3): 688–695.

https://doi.org/10.1182/blood-2008-05-160184

Published: 2009

Includes: Supplemental data

Journal Articles

Evidence for Increased Red Cell Turnover in Unexplained Anemia in Patients Over 70 Years of Age

Jeff Friedman, MD, PhD, Jill Waalen, MD, MPH, Alisa Takeda, Ernest Beutler, MD

Blood (2008) 112 (11): 3445.

https://doi.org/10.1182/blood.V112.11.3445.3445

Published: 2008

Journal Articles

Association of SMAD3/4, COUP-Tf, HNF4α, C/EBPα, GATA2 and STAT5 to the Hamp1 Promoter

Pauline Lee, PhD, Jaroslav Truksa, PhD, Ernest Beutler, MD

Blood (2008) 112 (11): 3837.

https://doi.org/10.1182/blood.V112.11.3837.3837

Published: 2008

Journal Articles

Inhibition of Hamp1 Expression by TMPRSS6, GDF15, PIAS4 and SMAD6 Utilize Several Target Sites in the Hamp1 Promoter

Jaroslav Truksa, PhD, Pauline Lee, PhD, Ernest Beutler, MD

Blood (2008) 112 (11): 3838.

https://doi.org/10.1182/blood.V112.11.3838.3838

Published: 2008

Journal Articles

Response: Screening for treatable disease is better than just screening for hemochromatosis

Jill Waalen, Vincent J. Felitti, Terri Gelbart, Ernest Beutler

Blood (2008) 111 (7): 3897.

https://doi.org/10.1182/blood-2008-01-132977

Published: 2008

Journal Articles

Screening for hemochromatosis by measuring ferritin levels: a more effective approach

Jill Waalen, Vincent J. Felitti, Terri Gelbart, Ernest Beutler

Blood (2008) 111 (7): 3373–3376.

https://doi.org/10.1182/blood-2007-07-102673

Published: 2008

Journal Articles

Glucose-6-phosphate dehydrogenase deficiency: a historical perspective

Ernest Beutler

Blood (2008) 111 (1): 16–24.

https://doi.org/10.1182/blood-2007-04-077412

Published: 2008

Journal Articles

The Mask Mutation Identifies TMPRSS6 as an Essential Suppressor of Hepcidin Gene Expression, Required for Normal Uptake of Dietary Iron.

Ernest Beutler, MD, Pauline Lee, PhD, Terri Gelbart, BS, Xin Du, PhD, Bruce Beutler, MD

Blood (2007) 110 (11): 3.

https://doi.org/10.1182/blood.V110.11.3.3

Published: 2007

Journal Articles

Transcriptional Regulation of Hepcidin by Iron.

Pauline Lee, PhD, Truksa Jaroslav, Ph.D., Hongfan Peng, Ernest Beutler, M.D.

Blood (2007) 110 (11): 2664.

https://doi.org/10.1182/blood.V110.11.2664.2664

Published: 2007

Journal Articles

Screening for Hemochromatosis by Measuring Ferritin Levels: A More Effective Approach.

Jill Waalen, MD, MPH, Ernest Beutler, MD

Blood (2007) 110 (11): 2673.

https://doi.org/10.1182/blood.V110.11.2673.2673

Published: 2007

Journal Articles

The distal location of the iron responsive region of the hepcidin promoter

Jaroslav Truksa, Pauline Lee, Hongfan Peng, Jonathan Flanagan, Ernest Beutler

Blood (2007) 110 (9): 3436–3437.

https://doi.org/10.1182/blood-2007-05-091108

Published: 2007

Journal Articles

Response: Correlation between Gaucher disease clinical severity and surrogate markers is weak

Ari Zimran, Deborah Elstein, Ernest Beutler

Blood (2007) 109 (1): 387–388.

https://doi.org/10.1182/blood-2006-07-034439

Published: 2007

Journal Articles

Investigation of the Iron Responsive Elements of the Hepcidin Promoter by In Vivo Imaging of Mice.

Jonathan Flanagan, PhD, Jaroslav Truksa, Ph.D., Hongfan Peng, Pauline Lee, Ph.D., Ernest Beutler, M.D.

Blood (2006) 108 (11): 1539.

https://doi.org/10.1182/blood.V108.11.1539.1539

Published: 2006

Journal Articles

Characterization of IL-6 Responsive Elements in Hepcidin Promoters at the Molecular Level: Lessons from the Two Closely Related Promoter Sequences, Murine Hepc1 and Hepc2 .

Jaroslav Truksa, PhD, Jonathan Flanagan, Ph.D., Pauline Lee, Ph.D., Ernest Beutler, M.D.

Blood (2006) 108 (11): 1555.

https://doi.org/10.1182/blood.V108.11.1555.1555

Published: 2006

Journal Articles

Low-dose therapy trumps high-dose therapy again in the treatment of Gaucher disease

Ari Zimran, Deborah Elstein, Ernest Beutler

Blood (2006) 108 (3): 802–803.

https://doi.org/10.1182/blood-2006-03-010801

Published: 2006

Journal Articles

The definition of anemia: what is the lower limit of normal of the blood hemoglobin concentration?

Ernest Beutler, Jill Waalen

Blood (2006) 107 (5): 1747–1750.

https://doi.org/10.1182/blood-2005-07-3046

Published: 2006

Journal Articles

Analysis of the Effect of Soluble Transferrin Receptor 1 (sTfR1) on Iron Metabolism in Mice.

Jonathan M. Flanagan, PhD, Hongfan Peng, Pauline L. Lee, PhD, Ernest Beutler, MD

Blood (2005) 106 (11): 3584.

https://doi.org/10.1182/blood.V106.11.3584.3584

Published: 2005

Journal Articles

A New Perspective on the Natural History of Hereditary Hemochromatosis.

Jill Waalen, MD, MPH, Ernest Beutler, MD

Blood (2005) 106 (11): 3595.

https://doi.org/10.1182/blood.V106.11.3595.3595

Published: 2005

Journal Articles

Three Kinships with ALAS2 P520L Mutations, Two in Association with Severe Iron Overload, and One with Sideroblastic Anemia and Severe Iron Overload.

Pauline L. Lee, PhD, James C. Barton, MD, Sreenivas V. Rao, MD, Ronald T. Acton, PhD, Brian K. Adler, MD, Ernest Beutler, MD

Blood (2005) 106 (11): 3723.

https://doi.org/10.1182/blood.V106.11.3723.3723

Published: 2005

Journal Articles

Examination of ALAS2 , ABC7 , Rag1 , and IL6 Genes as Candidate Modifiers of Iron Overload in HFE C282Y Homozygotes with Severe Iron Overload.

Pauline L. Lee, PhD, James C. Barton, MD, Carol West, AA, Karen Crain, BS, Sreenivas V. Rao, MD, Ernest Beutler, MD

Blood (2005) 106 (11): 3724.

https://doi.org/10.1182/blood.V106.11.3724.3724

Published: 2005

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Two BMP responsive elements, STAT, and bZIP/HNF4/COUP motifs of the hepcidin promoter are critical for BMP, SMAD1, and HJV responsiveness

Evidence for Increased Red Cell Turnover in Unexplained Anemia in Patients Over 70 Years of Age

Association of SMAD3/4, COUP-Tf, HNF4α, C/EBPα, GATA2 and STAT5 to the Hamp1 Promoter

Inhibition of Hamp1 Expression by TMPRSS6, GDF15, PIAS4 and SMAD6 Utilize Several Target Sites in the Hamp1 Promoter

Response: Screening for treatable disease is better than just screening for hemochromatosis

Screening for hemochromatosis by measuring ferritin levels: a more effective approach

Glucose-6-phosphate dehydrogenase deficiency: a historical perspective

The Mask Mutation Identifies TMPRSS6 as an Essential Suppressor of Hepcidin Gene Expression, Required for Normal Uptake of Dietary Iron.

Transcriptional Regulation of Hepcidin by Iron.

Screening for Hemochromatosis by Measuring Ferritin Levels: A More Effective Approach.

The distal location of the iron responsive region of the hepcidin promoter

Response: Correlation between Gaucher disease clinical severity and surrogate markers is weak

Investigation of the Iron Responsive Elements of the Hepcidin Promoter by In Vivo Imaging of Mice.

Characterization of IL-6 Responsive Elements in Hepcidin Promoters at the Molecular Level: Lessons from the Two Closely Related Promoter Sequences, Murine Hepc1 and Hepc2 .

Low-dose therapy trumps high-dose therapy again in the treatment of Gaucher disease

The definition of anemia: what is the lower limit of normal of the blood hemoglobin concentration?

Analysis of the Effect of Soluble Transferrin Receptor 1 (sTfR1) on Iron Metabolism in Mice.

A New Perspective on the Natural History of Hereditary Hemochromatosis.

Three Kinships with ALAS2 P520L Mutations, Two in Association with Severe Iron Overload, and One with Sideroblastic Anemia and Severe Iron Overload.

Examination of ALAS2 , ABC7 , Rag1 , and IL6 Genes as Candidate Modifiers of Iron Overload in HFE C282Y Homozygotes with Severe Iron Overload.

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American Society of Hematology

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