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Duncan H. Mak, MS
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Journal Articles

MLN0128, a Second-Generation mTOR Kinase Inhibitor, Disrupts Survival Signaling and Triggers Apoptosis in AML

Zhihong Zeng, MD, Rui-Yu Wang, MD PhD, Yuexi Shi, MD, Yihua Qiu, MD, Duncan H Mak, MS, Kevin Coombes, PhD, Suk Young Yoo, PhD, Katti Jessen, Yi Liu, PhD, Christian Rommel, PhD, Hagop M. Kantarjian, MD, Steven M. Kornblau, MD, David Fruman, PhD, Michael Andreeff, MD PhD, Marina Konopleva, MD PhD
Journal: Blood
Blood (2014) 124 (21): 3613.
https://doi.org/10.1182/blood.V124.21.3613.3613
Published: 2014
Journal Articles

Combination of Tyrosine Kinase Inhibitor with β-Catenin/CBP Modulator C82 Reverses TKI Resistance, Eradicates Quiescent CML Stem/Progenitors Cells, and Overcomes MSC-Associated Microenvironmental Protection

Hongsheng Zhou, MDPhD, Po Yee Mak, Hong Mu, MD PhD, Duncan H Mak, MS, Hiroyuki Kouji, Marina Konopleva, MD PhD, Jorge E. Cortes, Michael Andreeff, MD PhD, Bing Z Carter, PhD
Journal: Blood
Blood (2014) 124 (21): 401.
https://doi.org/10.1182/blood.V124.21.401.401
Published: 2014
Journal Articles

Triptolide Induces Cell Death Independent of Cellular Responses to Imatinib in Blast Crisis CML Cells and Sensitizes Imatinib.

Duncan H. Mak, MS, Wendy D. Schober, BS, Wenjing Chen, MD, Jorge E. Cortes, MD, Hagop M. Kantarjian, MD, Michael Andreeff, MD, PhD., Bing Z. Carter, PhD
Journal: Blood
Blood (2007) 110 (11): 1610.
https://doi.org/10.1182/blood.V110.11.1610.1610
Published: 2007
Journal Articles

Inhibition of KSP by ARRY-520 Induces Cell Cycle Block and Cell Death Via the Mitochondrial Pathway in AML Cells.

Bing Z. Carter, PhD, Duncan H. Mak, MS, Wendy D. Schober, BS, Richard Woessner, PhD, Stefan Gross, PhD, David Harris, BS, Zeev Estrov, MD, Michael Andreeff, MD, PhD
Journal: Blood
Blood (2007) 110 (11): 2782.
https://doi.org/10.1182/blood.V110.11.2782.2782
Published: 2007