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Journal Articles

Anti-CD20-Mediated B Cell Depletion Is Associated with Reduced Osteoclastogenic Signals and Bone Mass Preservation: Clinical Observation in Patients with Follicular Lymphoma Supplemented By Animal Studies in a Murine Model

Albert Kolomansky, MD, Irit Kay, MD, Nathalie Ben-Califa, PhD, Anton Gorodov, BSc, Zamzam Awida, BSc, Ofer Sadovnic, MD, Maria Ibrahim, BSc, Tamar Liron, PhD, Sahar Hiram-Bab, PhD, Howard S. Oster, MD PhD, Nadav Sarid, MD, Chava Perry, MD PhD, Yankel Gabet, DMD, PhD, Moshe Mittelman, MD, Drorit Neumann, PhD

Blood (2020) 136 (Supplement 1): 13.

https://doi.org/10.1182/blood-2020-142295

Published: 2020

Journal Articles

B Cell Specific Knockdown of the Erythropoietin (EPO) Receptor Attenuates EPO-Induced Bone Loss in Mice

Albert Kolomansky, MD, Naamit Deshet-Unger, PhD, Nathalie Ben-Califa, PhD, Zamzam Awida, Maria Ibrahim, B.Sc., Tamar Liron, PhD, Sahar Hiram-Bab, PhD, Howard S. Oster, MD PhD, Moshe Mittelman, MD, Martina Rauner, PhD, Ben Wielockx, PhD, Yankel Gabet, DMD, PhD, Drorit Neumann, PhD

Blood (2019) 134 (Supplement_1): 939.

https://doi.org/10.1182/blood-2019-127092

Published: 2019

Journal Articles

Erythropoietin (EPO) Regulates Bone Mass Via EPO Receptors on Myeloid and Lymphocytic Cells

Sahar Hiram-Bab, PhD, Albert Kolomansky, MD, Naamit Deshet-Unger, PhD, Nathalie Ben-Califa, PhD, Tamar Liron, PhD, Martina Rauner, PhD, Ben Wielockx, PhD, Moshe Mittelman, MD, Howard S. Oster, MD PhD, Yankel Gabet, DMD, PhD, Drorit Neumann, PhD

Blood (2018) 132 (Supplement 1): 846.

https://doi.org/10.1182/blood-2018-99-111643

Published: 2018

Journal Articles

Depletion of Mature B Cells By Anti CD20-Directed Antibody Induces Trabecular Bone Loss in Young Mice: An Alert for Clinicians?

Albert Kolomansky, MD, Naamit Deshet-Unger, PhD, Alina Ostrovsky, Nathalie Ben-Califa, PhD, Sahar Hiram-Bab, PhD, Tamar Liron, PhD, Howard S. Oster, MD PhD, Moshe Mittelman, MD, Yankel Gabet, DMD, PhD, Drorit Neumann, PhD

Blood (2017) 130 (Supplement 1): 5642.

https://doi.org/10.1182/blood.V130.Suppl_1.5642.5642

Published: 2017

Journal Articles

Immune Dysfunction in Patients with MDS Is Partially Corrected in EPO-Treated Patients: Differences According to WHO Classification

Howard S Oster, MD PhD, Naamit Deshet-Unger, MSc, Drorit Neumann, PhD, Moshe Mittelman, MD, Nir Maaravi, MD, Sara Prutchi-Sagiv, PhD, Golishevski Nataliya, MD

Blood (2016) 128 (22): 3165.

https://doi.org/10.1182/blood.V128.22.3165.3165

Published: 2016

Journal Articles

Recombinant Erythropoietin and Darbepoetin Alpha Exert a Similar Dose-Dependent Osteopenic Effect Which May Advocate for "Start Low, Go Slow" Dosing Strategy in Clinical Practice

Kolomansky Albert, MD, Sahar Hiram-Bab, PhD, Naamit Deshet-Unger, MSc, Nathalie Ben-Califa, PhD, Dafna Gilboa, MSc, Tamar Liron, PhD, Howard S Oster, MD PhD, Moshe Mittelman, MD, Yankel Gabet, DMD, PhD, Drorit Neumann, PhD

Blood (2016) 128 (22): 2445.

https://doi.org/10.1182/blood.V128.22.2445.2445

Published: 2016

Journal Articles

Transdifferentiation of Bone Marrow Pro-B Cells into Bone-Resorbing Osteoclasts- an Unexpected Role for Erythropoietin

Naamit Deshet-Unger, MSc, Sahar Hiram-Bab, PhD, Nathalie Ben-Califa, PhD, Dafna Gilboa, MSc, Tamar Liron, PhD, Kolomansky Albert, MD, Howard S Oster, MD PhD, Moshe Mittelman, MD, Yankel Gabet, DMD, PhD, Drorit Neumann, PhD

Blood (2016) 128 (22): 5043.

https://doi.org/10.1182/blood.V128.22.5043.5043

Published: 2016

Journal Articles

Erythropoietin Mediated Increase in Monocyte-Derived Liver Macrophages; A Role for Kupffer Cells?

Dafna Gilboa, Yasmin Haim-Ohana, Nathali Ben-Califa, PhD, Naamit Deshet-Unger, MS, Sahar Bab-Hiram, PhD, Max Gassmann, DVM, Moshe Mittelman, MD, Drorit Neumann, PhD

Blood (2015) 126 (23): 2201.

https://doi.org/10.1182/blood.V126.23.2201.2201

Published: 2015

Journal Articles

Erythropoietin May Affect B-Cell Maturation and Plasma Cell Antibody Production in Mice

Howard S Oster, MD PhD, Naamit Deshet-Unger, MS, Max Gassmann, DVM, Moshe Mittelman, MD, Drorit Neumann, PhD

Blood (2015) 126 (23): 4620.

https://doi.org/10.1182/blood.V126.23.4620.4620

Published: 2015

Journal Articles

Erythropoietin Stimulates Bone Resorption Via Direct Activation of the Monocytic Lineage and Via Increased RANKL Production By B Cells and Osteoblasts

Sahar Hiram-Bab, PhD, Naamit Deshet, M.Sc., Tamar Liron, PhD, Moshe Mittelman, MD, Max Gassmann, DVM, Martina Rauner, PhD, Kristin Franke, Ben Wielockx, PhD, Yankel Gabet, DMD, PhD, Drorit Neumann, PhD

Blood (2014) 124 (21): 247.

https://doi.org/10.1182/blood.V124.21.247.247

Published: 2014

Journal Articles

Liver Macrophages (Kupffer cells) As Novel Targets of Erythropoietin

Dafna Gilboa, M.Sc, Yasmin Ohana Haim, M.Sc., Naamit Deshet, M.Sc., Mor Gross, M.Sc., Nathalie Ben-Califa, PhD, Max Gassmann, DVM, Miriam C. Souroujon, PhD, Moshe Mittelman, MD, Drorit Neumann, PhD

Blood (2014) 124 (21): 4351.

https://doi.org/10.1182/blood.V124.21.4351.4351

Published: 2014

Journal Articles

Erythropoietin Potentiates The Immune System Yet Induces Bone Resorption In a Myeloma Mouse Model

Naamit Deshet-Unger, MSc, Sahar Hiram-Bab, PhD, Mor Gross, Yasmin Haim-Ohana, Miriam C. Souroujon, PhD, Howard S. Oster, MD, PhD, Moshe Mittelman, MD, Yankel Gabet, DMD, PhD, Drorit Neumann, PhD

Blood (2013) 122 (21): 1849.

https://doi.org/10.1182/blood.V122.21.1849.1849

Published: 2013

Journal Articles

Polycythemia-Inducing Mutations In The Erythropoietin Receptor (EPOR): Mechanism and Function Elucidated By EGFR– EPOR Chimeras

Mor Gross, Nathalie Ben-Califa, PhD, Hans Carl Hasselbalch, MD, DMSc, Mary Frances McMullin, MD, Melanie Percy, PhD, Celeste Bento, MD, Holger Cario, MD, Milen Minkov, MD, PhD, Drorit Neumann, PhD

Blood (2013) 122 (21): 2174.

https://doi.org/10.1182/blood.V122.21.2174.2174

Published: 2013

Journal Articles

Sensitive and Specific Antibody Probes Directed Against The Erythropoietin Receptor – From Basic Studies To Clinical Implementation

Blood (2013) 122 (21): 2175.

https://doi.org/10.1182/blood.V122.21.2175.2175

Published: 2013

Journal Articles

Erythropoietin-Associated Increase in the Proportion of Kupffer Cells

Yasmin Haim Ohana, Naamit Deshet, Miriam Souroujon, PhD, Max Gassmann, DVM, Moshe Mittelman, MD, Drorit Neumann, PhD

Blood (2012) 120 (21): 3266.

https://doi.org/10.1182/blood.V120.21.3266.3266

Published: 2012

Journal Articles

Erythropoietin Treatment in Multiple Myeloma – Friend or Foe?

Naamit Deshet-Unger, Msc, Sahar Hiram-Bab, PhD, Yasmin Haim Ohana, Mor Gross, Miriam Souroujon, PhD, Moshe Mittelman, MD, Drorit Neumann, PhD

Blood (2012) 120 (21): 5013.

https://doi.org/10.1182/blood.V120.21.5013.5013

Published: 2012

Journal Articles

Erythropoietin Treatment Is Associated with Decreased Blood Glucose Levels: A Preliminary Study in Hematologic Patients

Howard S Oster, MD, PhD, Moran Gvili, BA, Odelia Katz, PhD, Michael Hoffman, MD, Drorit Neumann, PhD, Moshe Mittelman, MD

Blood (2011) 118 (21): 4793.

https://doi.org/10.1182/blood.V118.21.4793.4793

Published: 2011

Journal Articles

Dexamethasone Reduces Viability of Bone Marrow Derived Macrophages

Yasmin Ohana, Miriam C Souroujon, PhD, Moshe Mittelman, MD, Drorit Neumann, PhD

Blood (2011) 118 (21): 4732.

https://doi.org/10.1182/blood.V118.21.4732.4732

Published: 2011

Journal Articles

Erythropoietin Treatment Leads to Reduced Blood Glucose Levels and Body Mass: Insights From Murine Models.

Odelia Katz, PhD, Matthew Stuible, Nataliya Golishevski, MD, Lilach Lifshitz, MD/PhD-student, Michel Tremblay, PhD, FRSC, Max Gassman, PhD, Howard S Oster, MD, PhD, Moshe Mittelman, MD, Drorit Neumann, PhD

Blood (2009) 114 (22): 4557.

https://doi.org/10.1182/blood.V114.22.4557.4557

Published: 2009

Journal Articles

Erythropoietin as a Novel Pro-Inflammatory Mediator of Macrophages.

Lilach Lifshitz, MD/PhD, student, Galit Tabak, MA, student, Max Gassman, PhD, Moshe Mittelman, MD, Drorit Neumann, PhD

Blood (2009) 114 (22): 3596.

https://doi.org/10.1182/blood.V114.22.3596.3596

Published: 2009

NARROW

Anti-CD20-Mediated B Cell Depletion Is Associated with Reduced Osteoclastogenic Signals and Bone Mass Preservation: Clinical Observation in Patients with Follicular Lymphoma Supplemented By Animal Studies in a Murine Model

B Cell Specific Knockdown of the Erythropoietin (EPO) Receptor Attenuates EPO-Induced Bone Loss in Mice

Erythropoietin (EPO) Regulates Bone Mass Via EPO Receptors on Myeloid and Lymphocytic Cells

Depletion of Mature B Cells By Anti CD20-Directed Antibody Induces Trabecular Bone Loss in Young Mice: An Alert for Clinicians?

Immune Dysfunction in Patients with MDS Is Partially Corrected in EPO-Treated Patients: Differences According to WHO Classification

Recombinant Erythropoietin and Darbepoetin Alpha Exert a Similar Dose-Dependent Osteopenic Effect Which May Advocate for "Start Low, Go Slow" Dosing Strategy in Clinical Practice

Transdifferentiation of Bone Marrow Pro-B Cells into Bone-Resorbing Osteoclasts- an Unexpected Role for Erythropoietin

Erythropoietin Mediated Increase in Monocyte-Derived Liver Macrophages; A Role for Kupffer Cells?

Erythropoietin May Affect B-Cell Maturation and Plasma Cell Antibody Production in Mice

Erythropoietin Stimulates Bone Resorption Via Direct Activation of the Monocytic Lineage and Via Increased RANKL Production By B Cells and Osteoblasts

Liver Macrophages (Kupffer cells) As Novel Targets of Erythropoietin

Erythropoietin Potentiates The Immune System Yet Induces Bone Resorption In a Myeloma Mouse Model

Polycythemia-Inducing Mutations In The Erythropoietin Receptor (EPOR): Mechanism and Function Elucidated By EGFR– EPOR Chimeras

Sensitive and Specific Antibody Probes Directed Against The Erythropoietin Receptor – From Basic Studies To Clinical Implementation

Erythropoietin-Associated Increase in the Proportion of Kupffer Cells

Erythropoietin Treatment in Multiple Myeloma – Friend or Foe?

Erythropoietin Treatment Is Associated with Decreased Blood Glucose Levels: A Preliminary Study in Hematologic Patients

Dexamethasone Reduces Viability of Bone Marrow Derived Macrophages

Erythropoietin Treatment Leads to Reduced Blood Glucose Levels and Body Mass: Insights From Murine Models.

Erythropoietin as a Novel Pro-Inflammatory Mediator of Macrophages.

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American Society of Hematology

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American Society of Hematology

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