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Journal Articles

A Novel Gene Expression Classifier Enriches for Single Agent Clinical Activity of CC-122, a Cereblon Modulator, Administered Orally to Relapsed or Refractory Diffuse Large B-Cell Lymphoma Subjects: Results from the Phase I CC-122-ST-001 Study

Blood (2017) 130 (Supplement 1): 4118.

https://doi.org/10.1182/blood.V130.Suppl_1.4118.4118

Published: 2017

Journal Articles

Establishment and Characterization of a Patient-Derived Model of ALK-Positive Anaplastic Large Cell Lymphoma

Michael J Wick, PhD, Elena Helman, PhD, Teresa L Vaught, DVM, Monica Farley, BS, Drew W Rasco, MD, Lon Smith, MD, Anthony Tolcher, MD, Amita Patnaik, MD, Michael Clark, PhD, Kyriakos P Papadopoulos, MD

Blood (2015) 126 (23): 5121.

https://doi.org/10.1182/blood.V126.23.5121.5121

Published: 2015

Journal Articles

ASN002: A Potent Dual SYK/JAK Inhibitor Currently in a Phase I/II Study Shows Strong Antitumor Activity in Preclinical Studies

Niranjan S. Rao, PhD, Sanjeeva Reddy, PhD, Gupta Sandeep, PhD, Nitin K Damle, PhD, Venkatesan M Aranapakam, PhD, Scott Thompson, PhD, Roger Smith, PhD, Terry Plasse, MD, Penelope Bristow, MS, Anthony Tolcher, MD, Kyriakos P Papadopoulos, MD, Amita Patnaik, MD, Drew W Rasco, MD

Blood (2015) 126 (23): 4009.

https://doi.org/10.1182/blood.V126.23.4009.4009

Published: 2015

Journal Articles

CC-122 Expands Activated and Memory CD4 and CD8 T Cells In Vivo and Induces T Cell Activation Ex Vivo in Subjects with Relapsed or Refractory Diffuse Large B Cell Lymphoma and Multiple Myeloma

Blood (2015) 126 (23): 2704.

https://doi.org/10.1182/blood.V126.23.2704.2704

Published: 2015

Journal Articles

CC-122 Dosing on a Novel Intermittent Schedule Mitigates Neutropenia and Maintains Clinical Activity in Subjects with Relapsed or Refractory Diffuse Large B Cell Lymphoma

Cecilia Carpio, MD, Loïc Ysebaert, MDPhD, Raúl Cordoba, MD, Armando Santoro, MD, José Antonio López-Martín, MD, Juan Manuel Sancho, MD PhD, Carlos Panizo, PhD, Mecide Meric Gharibo, MD, Drew W Rasco, MD, Anne-Marie Stoppa, MD, Sylvia Damian, MD, Xin Wei, Patrick Hagner, PhD, Kristen Hege, Soraya Carrancio, PhD, Anita K. Gandhi, PhD, Michael Pourdehnad, MD, Vincent Ribrag, MD

Blood (2015) 126 (23): 1494.

https://doi.org/10.1182/blood.V126.23.1494.1494

Published: 2015

Journal Articles

CC-122 Degrades the Lymphoid Transcription Factor Aiolos (IKZF3) By Modulating Cereblon and Shows Clinical Activity in a Phase Ib Study of Subjects with Relapsed or Refractory Non-Hodgkin’s Lymphoma and Multiple Myeloma

Vincent Ribrag, MD, Silvia Damien, MD, Mecide Gharibo, MD, Mercede Gironella, MD, Armando Santoro, MD, Drew W Rasco, MD, William Edenfield, MD, Xin Wei, PhD, Angela James, PhD, Patrick Hagner, PhD, Anita K. Gandhi, PhD, Rajesh Chopra, MD PhD, Jorge F. DiMartino, MD PhD, Michael Pourdehnad, MD, Anne-Marie Stoppa, MD

Blood (2014) 124 (21): 3500.

https://doi.org/10.1182/blood.V124.21.3500.3500

Published: 2014

Journal Articles

A First In Human Dose Escalation Study Of CC-122, A First-In-Class Pleiotropic Pathway Modulator™ (PPM) Compound In Subjects With Relapsed Or Refractory Solid Tumors, Multiple Myeloma and Non-Hodgkin’s Lymphoma

Drew W Rasco, MD, Anita K Gandhi, PhD, Angela James, PhD, Shaoyi Li, PhD, Edward O'Mara, MD, Rajesh Chopra, M.D., Ph.D., Jorge F. DiMartino, MD, PhD, Kent Shih, MD

Blood (2013) 122 (21): 2905.

https://doi.org/10.1182/blood.V122.21.2905.2905

Published: 2013

Journal Articles

Phase I Study of Intravenous PI3K Inhibitor Bay 80–6946: Preliminary Activity in Patients with Relapsed Non-Hodgkin Lymphoma (NHL) Treated in an MTD Expansion Cohort

Amita Patnaik, MD, Ramesh K Ramanathan, MD, Leonard Joseph Appleman, MD, PhD, Anthony W Tolcher, MD, FRCP, James M Mountz, MD, PhD, Muralidhar Beerham, MD, Glen J Weiss, MD, Drew W Rasco, MD, Michael T Lotze, MD, Frederico GS Toledo, MD, Matthew J Oborski, MS, Prabhu Rajagopalan, PhD, Michael Jeffers, PhD, Andrea Kelly, Isabelle Genvresse, MD

Blood (2012) 120 (21): 3704.

https://doi.org/10.1182/blood.V120.21.3704.3704

Published: 2012

NARROW

A Novel Gene Expression Classifier Enriches for Single Agent Clinical Activity of CC-122, a Cereblon Modulator, Administered Orally to Relapsed or Refractory Diffuse Large B-Cell Lymphoma Subjects: Results from the Phase I CC-122-ST-001 Study

Establishment and Characterization of a Patient-Derived Model of ALK-Positive Anaplastic Large Cell Lymphoma

ASN002: A Potent Dual SYK/JAK Inhibitor Currently in a Phase I/II Study Shows Strong Antitumor Activity in Preclinical Studies

CC-122 Expands Activated and Memory CD4 and CD8 T Cells In Vivo and Induces T Cell Activation Ex Vivo in Subjects with Relapsed or Refractory Diffuse Large B Cell Lymphoma and Multiple Myeloma

CC-122 Dosing on a Novel Intermittent Schedule Mitigates Neutropenia and Maintains Clinical Activity in Subjects with Relapsed or Refractory Diffuse Large B Cell Lymphoma

CC-122 Degrades the Lymphoid Transcription Factor Aiolos (IKZF3) By Modulating Cereblon and Shows Clinical Activity in a Phase Ib Study of Subjects with Relapsed or Refractory Non-Hodgkin’s Lymphoma and Multiple Myeloma

A First In Human Dose Escalation Study Of CC-122, A First-In-Class Pleiotropic Pathway Modulator™ (PPM) Compound In Subjects With Relapsed Or Refractory Solid Tumors, Multiple Myeloma and Non-Hodgkin’s Lymphoma

Phase I Study of Intravenous PI3K Inhibitor Bay 80–6946: Preliminary Activity in Patients with Relapsed Non-Hodgkin Lymphoma (NHL) Treated in an MTD Expansion Cohort

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American Society of Hematology

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ASH Publications

American Society of Hematology

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