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Dong-Myung Shin, Ph.D.
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Journal Articles

Unexpected Evidence That Chronic IGF-1 Deficiency In Laron Dwarf Mice Maintains High Levels of Hematopoietic Stem Cells (HSCs) In BM - Are HSCs Gradually Depleted From BM with Age In An IGF-1–dependent Manner? Implications for the Novel Effect of Caloric Restriction on the Hematopoietic Stem Cell Compartment and Longevity.

Janina Ratajczak, MD, PhD, Wu Wan, MS, Rui Liu, MB, BS, Dong-Myung Shin, Ph.D., Magdalena Kucia, PhD, Andrzej Bartke, Ph.D., Mariusz Z Ratajczak, MD, PhD, DSc
Journal: Blood
Blood (2010) 116 (21): 1551.
https://doi.org/10.1182/blood.V116.21.1551.1551
Published: 2010
Journal Articles

Polycomb Group Protein-Mediated Bivalent Domains Regulate Pluripotency of Oct4 + Very Small Embryonic-Like (VSEL) Stem Cells In Adult Bone Marrow

Dong-Myung Shin, Ph.D., Rui Liu, MB, BS, Wu Wan, MS, Janina Ratajczak, MD, PhD, Mariusz Z Ratajczak, MD, PhD, DSc, Magdalena Kucia, PhD
Journal: Blood
Blood (2010) 116 (21): 4788.
https://doi.org/10.1182/blood.V116.21.4788.4788
Published: 2010
Journal Articles

The Number of Very Small Embryonic Like Stem Cells (VSELs) Decreases During Aging In An IGF-1-Dependent Manner - a Novel Link Between Aging, Caloric Restriction, and the Size of the Stem Cell Pool

Dong-Myung Shin, Ph.D., Wu Wan, BS, Rui Liu, MB, BS, Janina Ratajczak, MD, PhD, Andrzej Bartke, Ph.D., Magdalena Kucia, PhD, Mariusz Z Ratajczak, MD, PhD, DSc
Journal: Blood
Blood (2010) 116 (21): 4796.
https://doi.org/10.1182/blood.V116.21.4796.4796
Published: 2010
Journal Articles

Quiescent Status of Very Small Embryonic Like Stem Cells (VSELs) Points to Pivotal Role of Autocrine Role of Insulin-Like Growth Factor-2 (Igf2) – Ras-Activating Guanine Nucleotide Exchange Factor (Rasgrf1) Axis in Regulating Proliferation of Embryonic Stem Cells.

Izabela Klich, Ph.D., Maciek Tarnowski, Ph.D., Dong-Myung Shin, Ph.D., Janina Ratajczak, M.D.,Ph.D., Magdalena Kucia, PhD, Mariusz Z Ratajczak, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 1484.
https://doi.org/10.1182/blood.V114.22.1484.1484
Published: 2009
Journal Articles

The Unique Pattern of Somatic Imprint in Oct-4 + Very Small Embryonic Like (VSEL) Stem Cells Isolated from Adult Tissues Further Supports Both Their Epiblast/Germ Line Origin and Explains Quiescent Status: Potential Modification of Somatic Imprint as a Key to Longevity?

Dong-Myung Shin, Ph.D., Ewa K Zuba-Surma, Ph.D., Mariusz Z Ratajczak, M.D., Ph.D., Magdalena Kucia
Journal: Blood
Blood (2008) 112 (11): 385.
https://doi.org/10.1182/blood.V112.11.385.385
Published: 2008