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Debra D Pittman, MS
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Journal Articles

In Vitro and In Vivo Characterization of Marstacimab, an Anti-TFPI Antibody

Chuenlei Parng, PhD, Macy Jin, PhD, Matthew Holsti, PhD, Susan Benard, Swapnil Rakhe, MS, Sunita R. Patel-Hett, PhD, Alison Joyce, Rob Webster, Debra D Pittman, MS
Journal: Blood
Blood (2019) 134 (Supplement_1): 2391.
https://doi.org/10.1182/blood-2019-130327
Published: 2019
Journal Articles

Antibodies Against the Erythroferrone N-Terminal Domain Prevent Hepcidin Suppression and Ameliorate Murine Thalassemia

Joao Arezes, BS, MSc, PhD, Niall Foy, Susan Benard, Anagha Sawant, May S Tam, Zachary Maben, Kirsty McHugh, Doris Quinkert, Andrew E Armitage, Sant-Rayn Pasricha, MD PhD, Pei-Jin Lim, Joe Frost, Edward LaVallie, Orla Cunningham, PhD, Matthew Lambert, Debra D Pittman, MS, John E. Murphy, PhD, Simon J Draper, Reema Jasuja, PhD, Alexander Drakesmith
Journal: Blood
Blood (2019) 134 (Supplement_1): 964.
https://doi.org/10.1182/blood-2019-130246
Published: 2019
Journal Articles

Adeno-Associated Virus Mediated Delivery of a TFPI Antibody Restores Hemostasis in Mouse Model of Hemophilia

Swapnil Rakhe, MS, Reema Jasuja, PhD, Rajani Shelke, Anagha Sawant, Suryanarayan Somanathan, PhD, John E. Murphy, PhD, Debra D Pittman, MS
Journal: Blood
Blood (2019) 134 (Supplement_1): 3357.
https://doi.org/10.1182/blood-2019-130054
Published: 2019
Journal Articles

Site-Directed Pegylation at Specific Sites Significantly Prolongs the Half-Life of A1A2A3-VWF By Markedly Attenuating LRP1-Mediated Clearance

Jamie M O'Sullivan, Judicael Fazavana, PhD, Alain Chan, PhD, Niamh Cooke, PhD, Virginie Terraube, Justin Cohen, PhD, Debra D Pittman, MS, Orla Cunningham, PhD, Matthew Lambert, James S O'Donnell, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1165.
https://doi.org/10.1182/blood-2018-99-114966
Published: 2018
Journal Articles

Efficacy of Anti-TFPI Antibody PF-06741086 Alone and in Combination with Activated Prothrombin Complex Concentrates in Mouse Hemophilia a Bleeding Model

Amey Barakat, Reema Jasuja, PhD, John E. Murphy, PhD, Debra D Pittman, MS
Journal: Blood
Blood (2018) 132 (Supplement 1): 2460.
https://doi.org/10.1182/blood-2018-99-118431
Published: 2018
Journal Articles

The Tissue Factor Pathway Inhibitor Antibody, PF-06741086, Increases Thrombin Generation in Rare Bleeding Disorder and Von Willebrand Factor Deficient Plasmas

Swapnil Rakhe, MS, Sunita R. Patel-Hett, PhD, Sheryl Bowley, PhD, John E. Murphy, PhD, Debra D Pittman, MS
Journal: Blood
Blood (2018) 132 (Supplement 1): 2462.
https://doi.org/10.1182/blood-2018-99-119674
Published: 2018
Journal Articles

A Neutralizing Monoclonal Antibody (PF-06741086) Against Tissue Factor Pathway Inhibitor in Combination with Activated Prothrombin Complex Concentrate Increases Hemostasis in Inhibitor Hemophilia Plasmas without Excessive Thrombin Generation

Swapnil Rakhe, MS, Sheryl Bowley, PhD, John E. Murphy, PhD, Debra D Pittman, MS
Journal: Blood
Blood (2018) 132 (Supplement 1): 3779.
https://doi.org/10.1182/blood-2018-99-119831
Published: 2018
Journal Articles

Transcriptomic Analysis Reveals Erythroferrone Modulates BMP6 Signaling Pathways Involved in Iron Homeostasis and Metabolism

Reema Jasuja, PhD, Anagha Sawant, Debra D Pittman, MS, Jie Quan
Journal: Blood
Blood (2018) 132 (Supplement 1): 1049.
https://doi.org/10.1182/blood-2018-99-118724
Published: 2018
Journal Articles

Safety and Tolerability of PF-04447943 across a Clinical Trial Program Including 277 Patients

Robert J Charnigo, MS, Beesan Tan, PhD, Denis Rybin, PhD, Debra D Pittman, MS, Krupa M. Sivamurthy, MBBS, MD, David Beidler, PhD, Nicholas Clarke, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3558.
https://doi.org/10.1182/blood.V130.Suppl_1.3558.3558
Published: 2017
Journal Articles

Elipsis: A Longitudinal Study of Electronic Patient-Reported Outcomes, Actigraphy and Biomarkers to Identify and Assess at-Home Vaso-Occlusive Crises in Adults and Adolescents with Sickle Cell Disease

Michael U. Callaghan, Patrick C. Hines, MD PhD, Debra D Pittman, MS, David Beidler, PhD, Denis Rybin, PhD, Ahmar Urooj Zaidi, MD BSc, Jennell White, PhD, Ke Liu, PhD, Bryan Hannan, MS, Xiufeng Gao, MD, Andreas M Pleil, PhD, Alexandra Barsdorf, PhD, Martin David, Pharm D, Melanie Simmons, PMP, PSM, Andrew L Frelinger, III, PhD, Alan D Michelson, MD, Nick Clarke, PhD, Robert J Charnigo, MS
Journal: Blood
Blood (2017) 130 (Supplement 1): 973.
https://doi.org/10.1182/blood.V130.Suppl_1.973.973
Published: 2017