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David Jarjoura, PhD
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Journal Articles

The Hsp90 Inhibitor 17-DMAG Increases SOCS3 and Regulates Cytokine Production, Migration and Cell Death in Chronic Lymphocytic Leukemia

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Erin K Hertlein, PhD, Timothy L. Chen, Rainer Claus, MD, Christoph Plass, PhD, Amy Lehman, David Jarjoura, PhD, Kami Maddocks, MD, Jeffrey A. Jones, MD, MPH, David M. Lucas, PhD, Amy J. Johnson, PhD, John C. Byrd, MD
Journal: Blood
Blood (2012) 120 (21): 1362.
https://doi.org/10.1182/blood.V120.21.1362.1362
Published: 2012
Journal Articles

Aberrant Epigenetic Suppression of the Ptprot Gene Encoding a Protein Tyrosine Phosphatase Targeting KIT in Acute Myeloid Leukemia

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Tasneem Motiwala, PhD, Satavisha Roy, Shujun Liu, Ph.D, Sebastian Schwind, MD, Rainer Claus, MD, Xiaokui Mo, PhD, Ramiro Garzon, MD, Hartmut Dohner, MD, Konstanze Dohner, MD, PhD, David Jarjoura, PhD, Christoph Plass, PhD, Guido Marcucci, MD, Samson T. Jacob, PhD
Journal: Blood
Blood (2012) 120 (21): 1322.
https://doi.org/10.1182/blood.V120.21.1322.1322
Published: 2012
Journal Articles

A Transgenic Mouse Model of Aggressive B-Cell Malignancy for Evaluating Anti-Human CD37 Therapeutics

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Kyle A Beckwith, B.S., Frank W Frissora, M.S., Matthew R Stefanovski, B.S., Jutta Deckert, Ph.D., Carlo M Croce, M.D., Xiaokui Mo, PhD, David Jarjoura, PhD, John C. Byrd, MD, Natarajan Muthusamy, DVM, Ph.D
Journal: Blood
Blood (2012) 120 (21): 188.
https://doi.org/10.1182/blood.V120.21.188.188
Published: 2012
Journal Articles

Comparative Assessment of Different Clinically Utilized CD20 Directed Antibodies in Chronic Lymphocytic Leukemia (CLL) Cells Reveals Divergent NK-Cell, Monocyte and Macrophage Properties,

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Sarwish Rafiq, MS, Jonathan P. Butchar, PhD, Carolyn Cheney, Xiaokui Mo, PhD, David Jarjoura, PhD, Susheela Tridandapani, PhD, Natarajan Muthusamy, DVM, Ph.D, John C. Byrd, MD
Journal: Blood
Blood (2011) 118 (21): 3717.
https://doi.org/10.1182/blood.V118.21.3717.3717
Published: 2011
Journal Articles

Targeting the Cyclin D - CDK4/6 - Rb Axis in Mantle Cell Lymphoma with the Novel Translation Inhibitor Silvestrol,

Free
Lapo Alinari, MD., Ph.D., Ryan B. Edwards, Courtney J. Prince, William H. Towns, Rajeswaran Mani, DVM, Amy Lehman, Xiaoli Zhang, PhD, MS, David Jarjoura, PhD, Li Pan, PhD, A. Douglas Kinghorn, PhD, DSc, Michael R. Grever, M.D., Robert A. Baiocchi, M.D., Ph.D., David M. Lucas, PhD
Journal: Blood
Blood (2011) 118 (21): 3498.
https://doi.org/10.1182/blood.V118.21.3498.3498
Published: 2011
Journal Articles

The Mll PTD and Flt3 ITD Double Knock-In Mouse Develops Acute Leukemia and Recapitulates Phenotypic, Molecular and Epigenetic Characteristics of the Counterpart Human Acute Myeloid Leukemia

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Nicholas Zorko, Susan P. Whitman, PhD, Kelsie Bernot, PhD, Myntee T. Ngangana, Ronald Siebenaler, Shujun Liu, Ph.D., Yue-Zhong Wu, MS, Chidimma Kalu, Xiaoli Zhang, PhD, MS, David Jarjoura, PhD, Zhiliang Xie, MD, Kenneth K. Chan, PhD, Adrienne M. Dorrance, PhD, Benjamin H. Lee, MD, PhD, Roger Briesewitz, PhD, Danilo Perrotti, MD, PhD, Guido Marcucci, MD, Michael A. Caligiuri, MD
Journal: Blood
Blood (2010) 116 (21): 150.
https://doi.org/10.1182/blood.V116.21.150.150
Published: 2010
Journal Articles

GlycoVariant Anti-CD37 Small Modular Immuno-Pharmaceutical Exhibits Superior Natural Killer Cell Mediated Cytotoxicity Against Chronic Lymphocytic Leukemia Cells at Low Concentrations and Low Antigen Density

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Sarwish Rafiq, MA, Carolyn M Cheney, BS, Gerard Lozanski, MD, Rosa Lapalombella, PhD, Xiaokui Mo, PhD, Anthony Siadak, MD, David Jarjoura, PhD, John C. Byrd, MD, Natarajan Muthusamy, DVM, PhD
Journal: Blood
Blood (2010) 116 (21): 1847.
https://doi.org/10.1182/blood.V116.21.1847.1847
Published: 2010
Journal Articles

Early Fludarabine Treatment of TCL-1 Transgenic Mice Promotes Drug Resistance through a Mechanism Not Involving p53 Mutations: Implications for Patients with Chronic Lymphocytic Leukemia (CLL).

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Michael D. De Lay, Amy J. Johnson, PhD, David M. Lucas, PhD, Darius T. Durr, Ellen M. Sass, Virginia M. Goettl, DVM, PhD, Amy Lehman, David Jarjoura, PhD, Michael R. Grever, MD, John C. Byrd, MD
Journal: Blood
Blood (2007) 110 (11): 3095.
https://doi.org/10.1182/blood.V110.11.3095.3095
Published: 2007