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David Fruman, PhD
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Journal Articles

Statins Enhance Killing of Multiple Myeloma Cells By the BCL-2 Inhibitor Venetoclax and the MCL-1 Inhibitor S63845

David Fruman, PhD, Dennis Juarez, B.S., Grace Diep, Undergraduate, Falisha Nguyen, Undergraduate, Vikas A. Gupta, MD PhD, Lawrence H. Boise, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4413.
https://doi.org/10.1182/blood-2019-131218
Published: 2019
Journal Articles

Combined Targeting of JAK2 with a Type II JAK2 Inhibitor and mTOR with a TOR Kinase Inhibitor Constitutes Synthetic Activity in JAK2-Driven Ph-like Acute Lymphoblastic Leukemia

Ce Shi, PhD, Lina Han, PhD, Qi Zhang, Kathryn G. Roberts, Eugene Park, Yoko Tabe, MD PhD, Rodrigo Omar Jacamo, PhD, Hong Mu, MD PhD, Shuo-Chieh Wu, Jin Zhou, Helen Ma, Zhihong Zeng, MD, Nitin Jain, MD, Elias J Jabbour, MD, Markus Muschen, MDPhD, Sarah K Tasian, MD, Charles G. Mullighan, MBBS, MSc, MD, David M. Weinstock, David Fruman, PhD, Marina Konopleva, MD PhD
Journal: Blood
Blood (2015) 126 (23): 2529.
https://doi.org/10.1182/blood.V126.23.2529.2529
Published: 2015
Journal Articles

MLN0128, a Second-Generation mTOR Kinase Inhibitor, Disrupts Survival Signaling and Triggers Apoptosis in AML

Zhihong Zeng, MD, Rui-Yu Wang, MD PhD, Yuexi Shi, MD, Yihua Qiu, MD, Duncan H Mak, MS, Kevin Coombes, PhD, Suk Young Yoo, PhD, Katti Jessen, Yi Liu, PhD, Christian Rommel, PhD, Hagop M. Kantarjian, MD, Steven M. Kornblau, MD, David Fruman, PhD, Michael Andreeff, MD PhD, Marina Konopleva, MD PhD
Journal: Blood
Blood (2014) 124 (21): 3613.
https://doi.org/10.1182/blood.V124.21.3613.3613
Published: 2014