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Daniel S. Wechsler, MD, PhD
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Journal Articles

Characterizing Proteins That Mediate CALM-AF10 Leukemogenesis

Rafi Kazi, MD, Waitman K. Aumann, MDMS, Pritha Bagchi, PhD, Daniel S. Wechsler, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 14.
https://doi.org/10.1182/blood-2020-138816
Published: 2020
Journal Articles

Single Cell Transcriptomics Revealed AML and Non-AML Cell Clusters Relevant to Relapse and Remission in Pediatric AML

Beena E Thomas, Pruthvi Perumalla, MS, Swati S Bhasin, PhD, Debasree Sarkar, PhD, Bhakti Dwivedi, PhD, Sunita I Park, MD, Deborah DeRyckere, BS,PhD, Curtis J. Henry, PhD, Sunil S. Raikar, MD, Christopher C. Porter, MD, Melinda Pauly, MD, Ryan J Summers, MD, Sharon M. Castellino, MD MSc, Daniel S. Wechsler, MD PhD, Douglas K Graham, MD PhD, Manoj Bhasin, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 24–25.
https://doi.org/10.1182/blood-2020-142513
Published: 2020
Journal Articles

The SIX1 homeobox Gene Is a Novel Therapeutic Target in CALM-AF10 Leukemogenesis

Waitman K. Aumann, MDMS, Catherine P. Lavau, DVM, PhD, Amanda Harrington, MD, Donald Tope, Amanda E. Conway, PhD, Hengbo Zhou, PhD, Heide Ford, PhD, Daniel S. Wechsler, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 38–39.
https://doi.org/10.1182/blood-2020-140754
Published: 2020
Journal Articles

SIX1 Is a Novel Effector Gene in CALM-AF10 Leukemia

Waitman K. Aumann, MDMS, Catherine P. Lavau, DVM, PhD, Amanda Harrington, MD, Amanda E. Conway, PhD, Daniel S. Wechsler, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5035.
https://doi.org/10.1182/blood-2019-130178
Published: 2019
Journal Articles

The SQSTM1-NUP214 Fusion Protein Cooperates with Crm1 to Activate Hoxa Genes and Drives Leukemogenesis in Mice

Waitman K. Aumann, MDMS, Sei-Gyung K. Sze, MD, Veerain Gupta, Katelyn Ripple, Sarah Port, Ralph Kehlenbach, PhD, Daniel S. Wechsler, MD PhD, Catherine P. Lavau, DVM, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1434.
https://doi.org/10.1182/blood-2019-130530
Published: 2019
Journal Articles

A Role for the CRM1 Nuclear Export Receptor in HOXA Gene Deregulation and CALM-AF10 Leukemogenesis

Waitman K. Aumann, MD, Jessica L. Heath, MD, Sei-Gyung K. Sze, MD, Amanda E. Conway, PhD, Catherine P. Lavau, DVM, PhD, Daniel S. Wechsler, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 369.
https://doi.org/10.1182/blood.V130.Suppl_1.369.369
Published: 2017
Journal Articles

The CRM1 Nuclear Export Receptor Activates HOXA Gene Expression in Leukemogenesis

Catherine P Lavau, DVM, PhD, Jessica L Heath, MD, William H Lee, Amanda E Conway, PhD, Daniel S Wechsler, MD PhD
Journal: Blood
Blood (2014) 124 (21): 2190.
https://doi.org/10.1182/blood.V124.21.2190.2190
Published: 2014
Journal Articles

Iron Deprivation Impairs Proliferation of CALM-AF10 leukemia Cells in Vitro and in Vivo

Jessica L Heath, MD, Joshua Weiss, Paula B. Scotland, PhD, Catherine P. Lavau, DVM, PhD, Daniel S. Wechsler, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 1386.
https://doi.org/10.1182/blood.V120.21.1386.1386
Published: 2012
Journal Articles

CALM Insufficiency Impairs Leukemia Cell Proliferation by Limiting Iron Uptake

Catherine P. Lavau, DVM, PhD, Jessica L Heath, MD, Paula B. Scotland, PhD, Daniel S. Wechsler, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 1478.
https://doi.org/10.1182/blood.V118.21.1478.1478
Published: 2011
Journal Articles

Complete Responses in Patients with Autoimmune Lymphoproliferative Syndrome (ALPS) Using the mTOR Inhibitor Sirolimus (rapamycin)

Davi d T. Teachey, MD, Robert J Greiner, MD, Dirk Schwabe, MD, Jack Bleesing, MD, PhD, Catherine Scott Manno, MD, Kathleen Sullivan, MD, PhD, Daniel S. Wechsler, MD, PhD, Stephan A. Grupp, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 2569.
https://doi.org/10.1182/blood.V112.11.2569.2569
Published: 2008
Journal Articles

Perturbed Endocytosis as a Mechanism of CALM-Dependent Leukemogenesis: Identification of Specific CALM Domains Required for Internalization and Demonstration of Prolonged JAK2 Signaling in Response to GM-CSF.

Natasha L. Brooks, MS, David A. Erichsen, Daniel S. Wechsler, MD, PhD
Journal: Blood
Blood (2007) 110 (11): 1817.
https://doi.org/10.1182/blood.V110.11.1817.1817
Published: 2007
Journal Articles

Perturbed Endocytosis by Leukemogenic CALM -Containing Fusion Proteins Is Associated with Prolonged Growth Factor Signaling and Enhanced Cellular Proliferation.

Mwe Mwe Chao, MD, David A. Erichsen, BS, Megan L. Krajewski, BS, Stefan K. Bohlander, MD, Daniel S. Wechsler, MD, PhD
Journal: Blood
Blood (2005) 106 (11): 2476.
https://doi.org/10.1182/blood.V106.11.2476.2476
Published: 2005
Journal Articles

Perturbed Endocytosis by CALM-Containing Fusion Proteins: A Leukemogenic Mechanism in AML.

Mwe Mwe Chao, MD, Ann C. Walker, BSc, Molly B. Pendergast, BSc, Stefan K. Bohlander, MD, Daniel S. Wechsler, MD, PhD
Journal: Blood
Blood (2004) 104 (11): 3380.
https://doi.org/10.1182/blood.V104.11.3380.3380
Published: 2004
Journal Articles

Mechanisms of Leukemogenesis by MLL-CALM: Characterization of a CALM-Derived Transcriptional Regulatory Domain.

Mwe Mwe Chao, MD, Emily J. Fox, Daniel S. Wechsler, MD, PhD.
Journal: Blood
Blood (2004) 104 (11): 3387.
https://doi.org/10.1182/blood.V104.11.3387.3387
Published: 2004