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Journal Articles

Interferon-Gamma Induced Changes in Gene Expression Dramatically Alter Neutrophil Phenotype

Michael Ellison, PhD, Natalie Briones, MS, Angelina Baroffio, John Murphy, Katherine Gowan, Bridget Sanford, Kenneth L. Jones, PhD, Daniel R. Ambruso, MD

Blood (2018) 132 (Supplement 1): 2398.

https://doi.org/10.1182/blood-2018-99-115314

Published: 2018

Journal Articles

Effects of Interferon-Gamma 1-b (IFN-Î³) on Neutrophil Function and Biochemistry in Patients with Chronic Granulomatous Disease

Daniel R. Ambruso, MD, Michael Ellison, PhD, Natalie Briones, MS, Alexander Tran, MS

Blood (2018) 132 (Supplement 1): 2400.

https://doi.org/10.1182/blood-2018-99-115683

Published: 2018

Journal Articles

Metabolic Abnormalities in G6PC3 Deficient Human Neutrophils Result in Severe Functional Defects

Christopher M. McKinney, MD, Michael A. Ellison, PhD, Natalie Briones, MS, Angelina Baroffio, MS, Julie A. Reisz, PhD, Angelo D'alessandro, PhD, Daniel R. Ambruso, MD

Blood (2016) 128 (22): 1024.

https://doi.org/10.1182/blood.V128.22.1024.1024

Published: 2016

Journal Articles

In Vivo Effects of Interferon-Gamma 1-b (IFN-γ) on Neutrophils

Daniel R. Ambruso, MD, Michael A Ellison, PhD, Natalie Briones, MS, Angelina Baroffio, MS

Blood (2016) 128 (22): 1026.

https://doi.org/10.1182/blood.V128.22.1026.1026

Published: 2016

Journal Articles

IFN-γ Alters the Expression of Diverse Immunity Related Genes in a Cell Culture Model of Maturing Neutrophils

Michael A Ellison, PhD, Christy M Gearheart, PhD, Christopher C. Porter, MD, Daniel R. Ambruso, MD

Blood (2016) 128 (22): 1328.

https://doi.org/10.1182/blood.V128.22.1328.1328

Published: 2016

Journal Articles

Peroxiredoxin 6 (Prdx6) Is Associated with Changes in Autophagy in Myeloid and Non-Myeloid Cells

Michael Ellison, PhD, Gail Thurman, BA, Daniel R. Ambruso, MD

Blood (2014) 124 (21): 1407.

https://doi.org/10.1182/blood.V124.21.1407.1407

Published: 2014

Journal Articles

Myeloid Cells Differentiated in the Presence of Interferon-γ (INF-γ) Compared to Mature Cells Exposed to This Cytokine Exhibit Different Phox Protein Expression and Nox2 Activity

Michael Ellison, PhD, Gail Thurman, BA, Daniel R. Ambruso, MD

Blood (2014) 124 (21): 4103.

https://doi.org/10.1182/blood.V124.21.4103.4103

Published: 2014

Journal Articles

Peroxiredoxin 6 Enhances Phagocyte NADPH Oxidase (phox) Activity in Response to Agonists Acting Via Cell Surface Receptors and Intracellular Signaling Pathways.

Michael A. Ellison, PhD, Daniel R. Ambruso, MD, Gail Thurman, BS

Blood (2012) 120 (21): 2139.

https://doi.org/10.1182/blood.V120.21.2139.2139

Published: 2012

Journal Articles

Adherence of Stored Apheresis Platelets (PLTs) with and without Pathogen Reduction Treatment (PRT) to Collagen in a Microfluidic Flow Chamber

Daniel R. Ambruso, MD, Ryan Seewald, BA, Jorge A Dipaola, MD, Gary Brodsky, PhD, Susanne Marschner, PhD, Raymond P. Goodrich, PhD

Blood (2012) 120 (21): 1179.

https://doi.org/10.1182/blood.V120.21.1179.1179

Published: 2012

Journal Articles

Expression of Platelet (PLT) P-Selectin and PLT-Neutrophil (PMN) Interaction After Treatment of Whole Blood with Mirasol ® PRT.

Daniel R. Ambruso, MD, Ryan Seewald, BA, Susanne Marschner, PhD, Raymond P. Goodrich, PhD

Blood (2012) 120 (21): 2288.

https://doi.org/10.1182/blood.V120.21.2288.2288

Published: 2012

Journal Articles

Neutrophil p29 Peroxiredoxin 6/aiPLA2 (p29 Prdx6) Enhances Superoxide Anion (O 2 - ) Production by Nox2: Role for the PLA2 Active Site

Daniel R Ambruso, MD, Michael Ellison, PhD, Gail Thurman, BS

Blood (2010) 116 (21): 926.

https://doi.org/10.1182/blood.V116.21.926.926

Published: 2010

Journal Articles

Expression of P-Selectin and Platelet-Neutrophil (PMN) Interactions In Untreated and Mirasol ® PRT Treated Platelet Concentrates During Routine Storage.

Daniel R Ambruso, MD, Raymond P Goodrich, PhD, Susanne Marschner, PhD

Blood (2010) 116 (21): 1123.

https://doi.org/10.1182/blood.V116.21.1123.1123

Published: 2010

Journal Articles

Neutrophil p29 Peroxiredoxin VI/aiPLA2 (p29 Prdx VI) Enhances Superoxide Production by the NADPH Oxidase in a Manner Dependent On the PLA2 Active Site.

Michael Ellison, Gail Thurman, Daniel R. Ambruso, MD

Blood (2009) 114 (22): 3592.

https://doi.org/10.1182/blood.V114.22.3592.3592

Published: 2009

Journal Articles

Neutrophil p29 Peroxiredoxin VI (Prdx VI) Enhances Bactericidal Activity and Chemotaxis in Myeloid Cells.

Michael Ellison, Gail Thurman, Daniel R. Ambruso, MD

Blood (2009) 114 (22): 1354.

https://doi.org/10.1182/blood.V114.22.1354.1354

Published: 2009

Journal Articles

Recovery of Donor Peripheral Blood Platelet Count Following Platelet Apheresis.

Larry J. Dumont, PhD, L. Lassahn, Peter A. Tomasulo, MD, Dennis Harpool, S. Pinkard, Neeta Rugg, Jose A. Cancelas, MD, S. Landry, Daniel R. Ambruso, MD, Chris Clementi, Robert Schuyler, PhD

Blood (2007) 110 (11): 2892.

https://doi.org/10.1182/blood.V110.11.2892.2892

Published: 2007

Journal Articles

Knockdown of Neutrophil p29 Peroxiredoxin (Prx) in Transgenic K562 Cells Expressing Phox Proteins Results in Diminished Oxidase Activity.

Daniel R. Ambruso, MD, Gail Thurman

Blood (2006) 108 (11): 1643.

https://doi.org/10.1182/blood.V108.11.1643.1643

Published: 2006

Journal Articles

Complement Activation in Transfusion Related Acute Lung Injury (TRALI).

Daniel R. Ambruso, MD, Christopher C. Silliman, MD, PhD, Marguerite Kelher, Gail Thurman, Patsy Giclas, PhD

Blood (2006) 108 (11): 954.

https://doi.org/10.1182/blood.V108.11.954.954

Published: 2006

Journal Articles

Cysteine Residues on Neutrophil p29 Peroxiredoxin Are Required for Enhanced Oxidase Activity.

Daniel R. Ambruso, MD, Gail Thurman, Carolina Gonzalez-Aller

Blood (2004) 104 (11): 654.

https://doi.org/10.1182/blood.V104.11.654.654

Published: 2004

Journal Articles

Complement Activation Associated with Transfusion Related Acute Lung Injury (TRALI).

Daniel R. Ambruso, MD, Patsy Giclas, PhD, Christopher C. Silliman, MD, PhD, Marguerite Kelher, MS, Steve Geier, PhD

Blood (2004) 104 (11): 2721.

https://doi.org/10.1182/blood.V104.11.2721.2721

Published: 2004

NARROW

Interferon-Gamma Induced Changes in Gene Expression Dramatically Alter Neutrophil Phenotype

Effects of Interferon-Gamma 1-b (IFN-Î³) on Neutrophil Function and Biochemistry in Patients with Chronic Granulomatous Disease

Metabolic Abnormalities in G6PC3 Deficient Human Neutrophils Result in Severe Functional Defects

In Vivo Effects of Interferon-Gamma 1-b (IFN-γ) on Neutrophils

IFN-γ Alters the Expression of Diverse Immunity Related Genes in a Cell Culture Model of Maturing Neutrophils

Peroxiredoxin 6 (Prdx6) Is Associated with Changes in Autophagy in Myeloid and Non-Myeloid Cells

Myeloid Cells Differentiated in the Presence of Interferon-γ (INF-γ) Compared to Mature Cells Exposed to This Cytokine Exhibit Different Phox Protein Expression and Nox2 Activity

Peroxiredoxin 6 Enhances Phagocyte NADPH Oxidase (phox) Activity in Response to Agonists Acting Via Cell Surface Receptors and Intracellular Signaling Pathways.

Adherence of Stored Apheresis Platelets (PLTs) with and without Pathogen Reduction Treatment (PRT) to Collagen in a Microfluidic Flow Chamber

Expression of Platelet (PLT) P-Selectin and PLT-Neutrophil (PMN) Interaction After Treatment of Whole Blood with Mirasol ® PRT.

Neutrophil p29 Peroxiredoxin 6/aiPLA2 (p29 Prdx6) Enhances Superoxide Anion (O 2 - ) Production by Nox2: Role for the PLA2 Active Site

Expression of P-Selectin and Platelet-Neutrophil (PMN) Interactions In Untreated and Mirasol ® PRT Treated Platelet Concentrates During Routine Storage.

Neutrophil p29 Peroxiredoxin VI/aiPLA2 (p29 Prdx VI) Enhances Superoxide Production by the NADPH Oxidase in a Manner Dependent On the PLA2 Active Site.

Neutrophil p29 Peroxiredoxin VI (Prdx VI) Enhances Bactericidal Activity and Chemotaxis in Myeloid Cells.

Recovery of Donor Peripheral Blood Platelet Count Following Platelet Apheresis.

Knockdown of Neutrophil p29 Peroxiredoxin (Prx) in Transgenic K562 Cells Expressing Phox Proteins Results in Diminished Oxidase Activity.

Complement Activation in Transfusion Related Acute Lung Injury (TRALI).

Cysteine Residues on Neutrophil p29 Peroxiredoxin Are Required for Enhanced Oxidase Activity.

Complement Activation Associated with Transfusion Related Acute Lung Injury (TRALI).

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American Society of Hematology

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American Society of Hematology

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