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Connie Lesnick, M.Sc
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Journal Articles

Targeted Inhibition of Axl Primes Chronic Lymphocytic Leukemia B-Cells for Apoptosis: Synergistic/Additive Effects in Combination with Bruton Tyrosine Kinase Inhibitors

Sutapa Sinha, PhD, Justin Boysen, Michael Nelson, Charla Secreto, Steven L. Warner, PhD, David J. Bearss, PhD, Connie Lesnick, M.Sc, Tait D. Shanafelt, MD, Neil E. Kay, MD, Asish K Ghosh, PhD
Journal: Blood
Blood (2014) 124 (21): 1946.
https://doi.org/10.1182/blood.V124.21.1946.1946
Published: 2014
Journal Articles

Activated Chronic Lymphocytic Leukemia B-Cells Preferentially Shed CD52 + Microvesicles, but Not CD19 + , and May Predict Therapeutic Outcome

Sutapa Sinha, PhD, Justin Boysen, Michael Nelson, Connie Lesnick, M.Sc, Tait D. Shanafelt, MD, Neil E. Kay, MD, Asish K Ghosh, PhD
Journal: Blood
Blood (2014) 124 (21): 1961.
https://doi.org/10.1182/blood.V124.21.1961.1961
Published: 2014
Journal Articles

The AKT Inhibitor MK2206 In Combination With Rituximab and Bendamustine Is Tolerable and Active In Relapsed Or Refractory Chronic Lymphocytic Leukemia: Results From a Phase 1 Study (NCCTG N1087 Alliance)

Wei Ding, MD, PhD, Tait D Shanafelt, MD, Clive S. Zent, MD, Jose F. Leis, MD, PhD, Betsy R. LaPlant, Timothy G. Call, MD, Curtis A Hanson, MD, Charles Erlichman, MD, Thomas M. Habermann, MD, Craig Reeder, MD, Daniel Nikcevich, Deborah Bowen, CNP, Michael J. Conte, PA-C, Justin Boysen, Charla Secreto, Connie Lesnick, M.Sc, Renee C. Tschumper, Diane F. Jelinek, PhD, Neil E. Kay, MD
Journal: Blood
Blood (2013) 122 (21): 2882.
https://doi.org/10.1182/blood.V122.21.2882.2882
Published: 2013
Journal Articles

Novel Pharmacological Agents Differentially Modulate Cytokine Release On CLL B-Cell-Stromal Cell Co-Culture: Implications for Stromal Rescue of CLL B-Cells From Chemotherapy

Connie Lesnick, M.Sc, Asish K Ghosh, PhD, Betsy R. LaPlant, Wei Ding, MD, PhD, Neil E. Kay, MD, Tait D. Shanafelt, MD
Journal: Blood
Blood (2012) 120 (21): 3927.
https://doi.org/10.1182/blood.V120.21.3927.3927
Published: 2012
Journal Articles

Allosteric Akt Inhibitor MK2206 Synergizes with Bendamustine in Promoting the Apoptosis of Chronic Lymphocytic Leukemia Cells and Selectively Targets B-Cell Receptor Mediated Cytokine Production

Wei Ding, MD, PhD, Tait D. Shanafelt, MD, Connie Lesnick, M.Sc, Traci Sassoon, Charla Secreto, Charles Erlichman, MD, Jose Leis, MD, PhD, Timothy G. Call, MD, Deborah Bowen, CNP, Shaji K. Kumar, MD, Neil E. Kay, MD
Journal: Blood
Blood (2012) 120 (21): 3928.
https://doi.org/10.1182/blood.V120.21.3928.3928
Published: 2012