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Journal Articles

All- Trans Retinoic Acid (ATRA) Targets IRF4 Deficient, NOTCH2-Activated B Cells from Chronic Gvhd Patients

Jonathan C. Poe, PhD, Wei Jia, MD, Hsuan Su, MS, Zhiguo Li, PhD, Frances T. Hakim, PhD, Steven Z. Pavletic, MD, Jeremy J. Rose, MS, David A Rizzieri, MD, Yiping Yang, MD PhD, Benny J. Chen, MD, Sarah Anand, MD, Jerome Ritz, MD, Christian W. Siebel, PhD, Nelson J. Chao, MD, Ivan Maillard, MD PhD, Stefanie Sarantopoulos, MD PhD

Blood (2016) 128 (22): 669.

https://doi.org/10.1182/blood.V128.22.669.669

Published: 2016

Journal Articles

Notch Signaling Mediated By Dll1/4 Notch Ligands Controls the Pathogenesis of Both Multi-Organ System Non-Sclerodermatous and Sclerodermatous Chronic Graft-Versus-Host Disease

Vedran Radojcic, MD, Ryan P Flynn, PhD, Jooho Chung, BS, Jing Du, Eric Perkey, BS, Katelyn Paz, Michael Zaiken, Ann Friedman, Minhong Yan, PhD, Christian W. Siebel, PhD, Bruce R. Blazar, MD, Ivan Maillard, MD PhD

Blood (2016) 128 (22): 805.

https://doi.org/10.1182/blood.V128.22.805.805

Published: 2016

Journal Articles

Targeting the Human Notch 2-BCR Axis: A Driver of B-Cell Hyper-Responsiveness in Active Chronic Graft-Versus Host Disease (cGVHD)

Jonathan C. Poe, PhD, Wei Jia, MD, Zhiguo Li, PhD, Frances T. Hakim, PhD, Steven Z. Pavletic, MD, Jeremy J. Rose, BA, David A. Rizzieri, MD, Yiping Yang, MD PhD, Benny J. Chen, MD, Michael Green, MD, Sarah Anand, MD, Christian W. Siebel, PhD, Ivan Maillard, MD PhD, Nelson J. Chao, MD, Stefanie Sarantopoulos, MD PhD

Blood (2015) 126 (23): 145.

https://doi.org/10.1182/blood.V126.23.145.145

Published: 2015

Journal Articles

Delta-like Ligands Expressed By Stromal Cells in Secondary Lymphoid Organs Deliver an Early Pulse of Notch Signaling and Drive T Cell Pathogenicity in Acute Graft-Versus-Host Disease

Jooho Chung, BS, Christen L. Ebens, MDMPH, Vedran Radojcic, MD, Ute Koch, PhD, Ann Friedman, BS, Ivy T. Tran, BS, Qian Chai, PhD, Lucas Onder, PhD, Minhong Yan, PhD, Pavan Reddy, MD, Bruce R. Blazar, MD, Burkhard Ludewig, PhD, Christian W. Siebel, PhD, Freddy Radtke, PhD, Ivan Maillard, MD PhD

Blood (2014) 124 (21): 841.

https://doi.org/10.1182/blood.V124.21.841.841

Published: 2014

Journal Articles

Loss of Notch Receptor-Ligand Engagement Leads to Increased Hematopoietic Stem and Progenitor Cell Egress and Mobilization

Lan Zhou, MD PhD, Weihuan Wang, MD PhD, Grant Zimmerman, Jay Myers, MS, Yuanshuai Huang, MD PhD, Vionnie W.C. Yu, PhD, Dan Huang, MD PhD, Shuiliang Yu, PhD, Yiwei Wang, MD PhD, Xiaoran Huang, MD, Jeongsup Shim, PhD, Minhong Yan, PhD, John Lowe, MD, Wei Xin, MD PhD, Pamela Stanley, PhD BSc, David T. Scadden, MD, Alex Y Huang, MD PhD, Christian W. Siebel, PhD

Blood (2014) 124 (21): 652.

https://doi.org/10.1182/blood.V124.21.652.652

Published: 2014

Journal Articles

Delta-Like Notch Ligands Expressed By Host Non-Hematopoietic Radioresistant Cells Regulate Graft-Versus-Host Disease and Extrathymic T Cell Development After Bone Marrow Transplantation

Christen L Ebens, MD, MPH, Jooho Chung, BS, Ute Koch, PhD, Ivy T Tran, BS, Ashley R Sandy-Sloat, PhD, Ann Friedman, BS, Bruce R Blazar, MD, Pavan Reddy, MD, Minhong Yan, PhD, Christian W Siebel, PhD, Freddy Radtke, PhD, Ivan Maillard, MD, PhD

Blood (2013) 122 (21): 2003.

https://doi.org/10.1182/blood.V122.21.2003.2003

Published: 2013

Journal Articles

In Vivo Blockade of Individual Notch Ligands and Receptors Provides a New Targeted Therapeutic Approach In Graft-Versus-Host Disease

Ivy T Tran, BS, Ashley R Sandy, BS, Alexis Carulli, BS, Gloria T Shan, BS, Vedran Radojcic, MD, Ann Friedman, BS, Amy Shelton, Linda C Samuelson, PhD, Minhong Yan, PhD, Christian W Siebel, PhD, Ivan Maillard, MD, PhD

Blood (2011) 118 (21): 819.

https://doi.org/10.1182/blood.V118.21.819.819

Published: 2011

NARROW

All- Trans Retinoic Acid (ATRA) Targets IRF4 Deficient, NOTCH2-Activated B Cells from Chronic Gvhd Patients

Notch Signaling Mediated By Dll1/4 Notch Ligands Controls the Pathogenesis of Both Multi-Organ System Non-Sclerodermatous and Sclerodermatous Chronic Graft-Versus-Host Disease

Targeting the Human Notch 2-BCR Axis: A Driver of B-Cell Hyper-Responsiveness in Active Chronic Graft-Versus Host Disease (cGVHD)

Delta-like Ligands Expressed By Stromal Cells in Secondary Lymphoid Organs Deliver an Early Pulse of Notch Signaling and Drive T Cell Pathogenicity in Acute Graft-Versus-Host Disease

Loss of Notch Receptor-Ligand Engagement Leads to Increased Hematopoietic Stem and Progenitor Cell Egress and Mobilization

Delta-Like Notch Ligands Expressed By Host Non-Hematopoietic Radioresistant Cells Regulate Graft-Versus-Host Disease and Extrathymic T Cell Development After Bone Marrow Transplantation

In Vivo Blockade of Individual Notch Ligands and Receptors Provides a New Targeted Therapeutic Approach In Graft-Versus-Host Disease

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ASH Publications

American Society of Hematology

All- Trans Retinoic Acid (ATRA) Targets IRF4 Deficient, NOTCH2-Activated B Cells from Chronic Gvhd Patients

Notch Signaling Mediated By Dll1/4 Notch Ligands Controls the Pathogenesis of Both Multi-Organ System Non-Sclerodermatous and Sclerodermatous Chronic Graft-Versus-Host Disease

Targeting the Human Notch 2-BCR Axis: A Driver of B-Cell Hyper-Responsiveness in Active Chronic Graft-Versus Host Disease (cGVHD)

Delta-like Ligands Expressed By Stromal Cells in Secondary Lymphoid Organs Deliver an Early Pulse of Notch Signaling and Drive T Cell Pathogenicity in Acute Graft-Versus-Host Disease

Loss of Notch Receptor-Ligand Engagement Leads to Increased Hematopoietic Stem and Progenitor Cell Egress and Mobilization

Delta-Like Notch Ligands Expressed By Host Non-Hematopoietic Radioresistant Cells Regulate Graft-Versus-Host Disease and Extrathymic T Cell Development After Bone Marrow Transplantation

In Vivo Blockade of Individual Notch Ligands and Receptors Provides a New Targeted Therapeutic Approach In Graft-Versus-Host Disease

Email alerts

ASH Publications

American Society of Hematology

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