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Chien-Hsing Chang, Ph.D.
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Journal Articles

Bispecific Hexavalant Antibodies With Enhanced Trogocytosis For Treatment Of Lupus

Edmund A Rossi, Ph.D, Rosana Michel, M.S., Chien-Hsing Chang, Ph.D, David M Goldenberg, ScD, MD
Journal: Blood
Blood (2013) 122 (21): 2282.
https://doi.org/10.1182/blood.V122.21.2282.2282
Published: 2013
Journal Articles

Immunornase Therapy Of Lymphoma With Novel CD22-Targeting Quadruple Ranpirnase

Donglin Liu, Ph.D., Thomas M Cardillo, Ph.D, David M Goldenberg, ScD, MD, Chien-Hsing Chang, Ph.D
Journal: Blood
Blood (2013) 122 (21): 3075.
https://doi.org/10.1182/blood.V122.21.3075.3075
Published: 2013
Journal Articles

A New Platform For Trivalent Bispecific Antibodies Used For T-Cell Redirected Killing Of B-Cell Malignancies

Diane L Rossi, M.S., Edmund A Rossi, Ph.D, David M Goldenberg, ScD, MD, Chien-Hsing Chang, Ph.D
Journal: Blood
Blood (2013) 122 (21): 3078.
https://doi.org/10.1182/blood.V122.21.3078.3078
Published: 2013
Journal Articles

CD22-Targeting Epratuzumab Down-Regulates Multiple BCR Regulators On the Surface of Normal, Lupus, and Malignant B Cells

Edmund A Rossi, Ph.D, Rosana Michel, M.S., Daniel J Wallace, MD, Chien-Hsing Chang, Ph.D, David M Goldenberg, ScD, MD
Journal: Blood
Blood (2012) 120 (21): 1357.
https://doi.org/10.1182/blood.V120.21.1357.1357
Published: 2012
Journal Articles

Prevention of Acute Graft-Versus-Host Disease in Human/Mouse Xenogeneic SCID Mouse Model by Humanized Anti-CD74 Monoclonal Antibody, Milatuzumab

Xiaochuan Chen, Ph.D, Chien-Hsing Chang, Ph.D, Rhona Stein, Ph.D, Thomas M Cardillo, Ph.D, David V. Gold, Ph.D., David M Goldenberg, ScD, MD
Journal: Blood
Blood (2012) 120 (21): 4105.
https://doi.org/10.1182/blood.V120.21.4105.4105
Published: 2012
Journal Articles

A Novel T-Cell Redirecting Anti-CD19-F(ab) 2 /CD3scFv Bispecific Antibody Exhibits Potent Lymphoma Cytotoxicity.

Diane L Rossi, M.S., Edmund A Rossi, Ph.D, Thomas M Cardillo, Ph.D, David M Goldenberg, ScD, MD, Chien-Hsing Chang, Ph.D
Journal: Blood
Blood (2012) 120 (21): 2762.
https://doi.org/10.1182/blood.V120.21.2762.2762
Published: 2012
Journal Articles

A New Class of Hexavalent Bispecific Antibodies and Immunocytokines with Enhanced Pharmacokinetics and Improved Efficacy in Vivo .

Edmund A Rossi, Ph.D, Thomas M Cardillo, Ph.D, David M Goldenberg, ScD, MD, Chien-Hsing Chang, Ph.D
Journal: Blood
Blood (2012) 120 (21): 2451.
https://doi.org/10.1182/blood.V120.21.2451.2451
Published: 2012
Journal Articles

Combination Therapy with FTY720 (Fingolimod) and Bispecific Anti-CD20/CD74 Antibodies in Mantle Cell Lymphoma,

Pankaj Gupta, Ph.D, Rosana Michel, M.S., David M Goldenberg, ScD, MD, Chien-Hsing Chang, Ph.D
Journal: Blood
Blood (2011) 118 (21): 3736.
https://doi.org/10.1182/blood.V118.21.3736.3736
Published: 2011
Journal Articles

Juxtaposing CD20 and CD74 with Novel Bispecific Antibodies Evokes Potent Cytotoxicity in Mantle Cell Lymphoma (MCL)

Pankaj Gupta, Ph.D, David M. Goldenberg, ScD, MD, Edmund A Rossi, Ph.D, Thomas M. Cardillo, Ph.D, John C. Byrd, MD, Natarajan Muthusamy, DVM, Ph.D, Richard R. Furman, MD, Chien-Hsing Chang, Ph.D
Journal: Blood
Blood (2011) 118 (21): 599.
https://doi.org/10.1182/blood.V118.21.599.599
Published: 2011
Journal Articles

A New Class of Dimeric α-Interferons (IFN-α) Made by the Dock and Lock (DNL) Method for Improved Cancer Therapy.

Edmund A. Rossi, PhD, William J. McBride, Ph.D., Diane L. Nordstrom, M.S., Preeti Trisal, M.S., Thomas M. Cardillo, Ph.D., David M. Goldenberg, M.D. Sc.D., Chien-Hsing Chang, Ph.D.
Journal: Blood
Blood (2007) 110 (11): 1396.
https://doi.org/10.1182/blood.V110.11.1396.1396
Published: 2007
Journal Articles

Multivalent Anti-CD20/Anti-CD22 Bispecific Antibody Fusion Proteins Made by the DNL Method Show Potent Lymphoma Cytotoxicity.

Edmund A. Rossi, PhD, Michele J. Losman, Ph.D., Diane L. Nordstrom, M.S., Thomas Cardillo, Ph.D., Meiyu Loo, M.S., John Kopinski, B.S., Zhengxing Qu, Ph.D., David M. Goldenberg, Sc.D., M.D., Chien-Hsing Chang, Ph.D.
Journal: Blood
Blood (2006) 108 (11): 2495.
https://doi.org/10.1182/blood.V108.11.2495.2495
Published: 2006
Journal Articles

Preclinical Safety and Efficacy of Two Novel Immunotoxins Consisting of Ranpirnase (Rap) Fused to an Internalizing Anti-CD74 Humanized IgG4 Antibody in Human Non-Hodgkin’s Lymphoma Xenografts.

Puja Sapra, PhD, Chien-Hsing Chang, Ph.D, Sailaja Vanama, Ph.D, Sharon Singh, BA, Hans J. Hansen, Ph.D, Ivan D. Horak, M.D, David M. Goldenberg, M.D
Journal: Blood
Blood (2005) 106 (11): 346.
https://doi.org/10.1182/blood.V106.11.346.346
Published: 2005