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Chester A. Metcalf, III
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Journal Articles

In vitro and in vivo activity of ATP-based kinase inhibitors AP23464 and AP23848 against activation-loop mutants of Kit

Amie S. Corbin, Shadmehr Demehri, Ian J. Griswold, Yihan Wang, Chester A. Metcalf, III, Raji Sundaramoorthi, William C. Shakespeare, Joseph Snodgrass, Scott Wardwell, David Dalgarno, John Iuliucci, Tomi K. Sawyer, Michael C. Heinrich, Brian J. Druker, Michael W. N. Deininger
Journal: Blood
Blood (2005) 106 (1): 227–234.
https://doi.org/10.1182/blood-2004-12-4771
Published: 2005
Includes: Supplemental data
Journal Articles

A Potent Src/Abl Kinase Inhibitor (Ap23464) Potently Inhibits the Growth of Myeloid Leukemic Cells Characterized by Flt3-Itd Expression, GM-CSF Dependency, or G-CSF Responsiveness Via an Abl-Independent Mechanism.

Jukka Kanerva, MD, PhD, Ogonna Nwawka, BS, Kevin Hwang, William C. Shakespeare, PhD, Chester A. Metcalf, III, PhD, Tomi K. Sawyer, PhD, Camille L. Bedrosian, MD, Seth J. Corey, MD
Journal: Blood
Blood (2004) 104 (11): 4479.
https://doi.org/10.1182/blood.V104.11.4479.4479
Published: 2004
Journal Articles

In Vitro and In Vivo Activity of the Src/Abl Kinase Inhibitor AP23464 and Analogs Against Activation Loop Mutants of KIT.

Amie S. Corbin, Shadmehr Demehri, Ian J. Griswold, Chester A. Metcalf, III, William C. Shakespeare, Joseph Snodgrass, Scott Wardwell, David C. Dalgarno, John Iuliucci, Tomi K. Sawyer, Brian J. Druker, Michael W. Deininger
Journal: Blood
Blood (2004) 104 (11): 793.
https://doi.org/10.1182/blood.V104.11.793.793
Published: 2004
Journal Articles

Inhibition of wild-type and mutant Bcr-Abl by AP23464, a potent ATP-based oncogenic protein kinase inhibitor: implications for CML

Thomas O'Hare, Roy Pollock, Eric P. Stoffregen, Jeffrey A. Keats, Omar M. Abdullah, Erika M. Moseson, Victor M. Rivera, Hao Tang, Chester A. Metcalf, III, Regine S. Bohacek, Yihan Wang, Raji Sundaramoorthi, William C. Shakespeare, David Dalgarno, Tim Clackson, Tomi K. Sawyer, Michael W. Deininger, Brian J. Druker
Journal: Blood
Blood (2004) 104 (8): 2532–2539.
https://doi.org/10.1182/blood-2004-05-1851
Published: 2004