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Carolina L. Bigarella, PhD
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Journal Articles

Loss of Foxo3 Reduces Erythroblast Apoptosis and Enhances RBC Production in Beta-Thalassemic Mice

Raymond Liang, B.S., Genís Campreciós, PhD, Carolina L. Bigarella, PhD, Saghi Ghaffari, MD PhD
Journal: Blood
Blood (2015) 126 (23): 756.
https://doi.org/10.1182/blood.V126.23.756.756
Published: 2015
Journal Articles

CXCR7 Participates in Chemotaxis and Homing Mediated By CXCL12

Rita de Cassia Carvalho Melo, MSc, Juliana M. Xavier-Ferrucio, PhD, Lauremilia Ricon, PhD, Karla Priscila Vieira Vieira Ferro, PhD, Carolina L. Bigarella, PhD, Gilberto C. Franchi, Jr., Alexandre Nowill, PhD MD, Sara Teresinha Olalla Saad, PhD MD
Journal: Blood
Blood (2015) 126 (23): 3601.
https://doi.org/10.1182/blood.V126.23.3601.3601
Published: 2015
Journal Articles

A Systems Approach Identifies Essential FOXO3 Functions in Erythroblast Enucleation Process

Raymond Liang, Genís Campreciós, PhD, Yan Kou, Ms, Kathleen E McGrath, PhD, Roberta Novak, Seana C Catherman, B.S., Pauline Rimmele, PhD, Carolina L. Bigarella, PhD, Emery H Bresnick, PhD, Dmitri Papatsenko, PhD, Avi Ma'ayan, Velia M. Fowler, PhD, James Palis, MD, Saghi Ghaffari, MD PhD
Journal: Blood
Blood (2014) 124 (21): 445.
https://doi.org/10.1182/blood.V124.21.445.445
Published: 2014
Journal Articles

Loss Of p53 Rescues The Defective Function Of Foxo3 -/- Hematopoietic Stem Cells But Enhances Their Predisposition To Malignancy

Carolina L. Bigarella, PhD, Pauline Rimmele, PhD, Rebeca Dieguez-Gonzalez, PhD, Raymond Liang, Brigitte Izac, MSc, Dmitri Papatsenko, PhD, Saghi Ghaffari, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 4199.
https://doi.org/10.1182/blood.V122.21.4199.4199
Published: 2013
Journal Articles

Acetylation Is Critical for Foxo3 Protein Stability and Activity in Hematopoietic Stem and Progenitor Cells

Carolina L. Bigarella, PhD, Pauline Rimmele, PhD, Raymond Liang, Yasaman Azodi, Brigitte Izac, MSc, Valentina d'Escamard, MSc, Saghi Ghaffari, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 1198.
https://doi.org/10.1182/blood.V120.21.1198.1198
Published: 2012
Journal Articles

Metabolic Pathways Control Normal and Beta-Thalassemic Erythroid Cell Maturation

Geníis Camprecióos, PhD, Xin Zhang, MD, PhD, Valentina D'Escamard, MSc, Pauline Rimmele, PhD, Carolina L. Bigarella, PhD, Brigitte Izac, MSc, Carlo Brugnara, M.D., Emery H Bresnick, PhD, Stefano Rivella, PhD, Saghi Ghaffari, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 369.
https://doi.org/10.1182/blood.V120.21.369.369
Published: 2012
Journal Articles

Foxo3-Mediated Redox Regulation Is Required for DNA Damage Response in Hematopoietic Stem Cells.

Carolina L. Bigarella, PhD, Pauline Rimmele, PhD, Brigitte Izac, MSc, Valentina d'Escamard, MSc, Saghi Ghaffari, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 2295.
https://doi.org/10.1182/blood.V120.21.2295.2295
Published: 2012
Journal Articles

SIRT1 Deacetylase Is Essential for Hematopoietic Stem Cell Activity Via Regulation of Foxo3.

Pauline Rimmele, PhD, Carolina L. Bigarella, PhD, Valentina d'Escamard, MSc, Brigitte Izac, MSc, David Sinclair, PhD, Saghi Ghaffari, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 2315.
https://doi.org/10.1182/blood.V120.21.2315.2315
Published: 2012