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Journal Articles

Level of Evidence for FDA Drug Approvals in Pivotal Clinical Trials of Hematological Malignancies

Samer Al Hadidi, MDMSc,FACP, Carlos A. Ramos, MD

Blood (2020) 136 (Supplement 1): 6.

https://doi.org/10.1182/blood-2020-136330

Published: 2020

Journal Articles

A Bank of CD30.CAR-Modified, Epstein-Barr Virus-Specific T Cells That Lacks Host Reactivity and Resists Graft Rejection for Patients with CD30-Positive Lymphoma

David H. Quach, PhD, Haran R. Ganesh, BS, Sachin Thakkar, PhD, Luis Becerra-Dominguez, BS, Birju Mehta, MS, Silvana Perconti, MS, Eric Anderson, BS, Emily M. Hsieh, MD, Olga Dakhova, MD, Huimin Zhang, BS, Bambi J. Grilley, RPh, Malcolm K. Brenner, MD PhD, Helen E. Heslop, MD DSc, Carlos A. Ramos, MD, Rayne H. Rouce, MD, Natalia Lapteva, PhD, Cliona M. Rooney, PhD

Blood (2020) 136 (Supplement 1): 16.

https://doi.org/10.1182/blood-2020-141491

Published: 2020

Journal Articles

Treatment of Severe, Drug-Refractory Viral Infections with Allogeneic, Off-the-Shelf Multi-Virus Specific T Cells in Patients Following HSCT: Results from a Phase 2 Study

Ifigeneia Tzannou, MD, Ayumi Watanabe, Bsc, Anastasia Papadopoulou, PhD, Manik Kuvalekar, Msc, Swati Naik, MBBS, Premal Lulla, MBBS, Robert A. Krance, MD, Carlos A. Ramos, MD, Helen E. Heslop, MD DSc, Ann M. Leen, PhD, Bilal Omer, MD

Blood (2020) 136 (Supplement 1): 2–3.

https://doi.org/10.1182/blood-2020-143037

Published: 2020

Journal Articles

T Cell Immunity Toward Viral- and Tumor-Antigens Is Preserved in MDS Patients

Hussein Hamad, MD, Wingchi K Leung, MD, Spyridoula Vasileiou, PhD, Shivani Mukhi, Quillan Huang, MD, George Carrum, MD, Carlos A. Ramos, MD, Rammurti Kamble, MD, LaQuisa C. Hill, MD, Ann M. Leen, PhD, Premal Lulla, MBBS

Blood (2019) 134 (Supplement_1): 4225.

https://doi.org/10.1182/blood-2019-126792

Published: 2019

Journal Articles

Novel Immunotherapeutic Approaches for Hodgkin Lymphoma

Barbara Savoldo, MD PhD, Natalie S Grover, MD, Carlos A. Ramos, MD, Gianpietro Dotti, MD

Blood (2019) 134 (Supplement_1): SCI-9.

https://doi.org/10.1182/blood-2019-121075

Published: 2019

Journal Articles

Adoptive T-Cell Therapy for Acute Lymphoblastic Leukemia Targeting Multiple Tumor Associated Antigens

Swati Naik, MBBS, Premal Lulla, MBBS, Ifigeneia Tzannou, MD, Robert A. Krance, MD, George Carrum, MD, Rammurti Kamble, MD, Carlos A. Ramos, MD, Catherine Robertson, Manik Kuvalekar, Ayumi Watanabe, Bambi J. Grilley, RPh, Juan F. Vera, MD, Helen E. Heslop, MDDSc, Ann M. Leen, PhD

Blood (2018) 132 (Supplement 1): 2693.

https://doi.org/10.1182/blood-2018-99-115465

Published: 2018

Journal Articles

Rapid Generation of Multivirus-Specific T Lymphocytes for the Prevention and Treatment of Respiratory Viral Infections

Spyridoula Vasileiou, PhD, Annie Turney, Manik Kuvalekar, Shivani Mukhi, Ayumi Watanabe, Premal Lulla, MBBS, Carlos A. Ramos, MD, Juan Vera, MD, Ifigeneia Tzannou, MD, Ann Leen, PhD

Blood (2018) 132 (Supplement 1): 3332.

https://doi.org/10.1182/blood-2018-99-113168

Published: 2018

Journal Articles

Safety and Efficacy of Multiantigen-Targeted T Cells for Multiple Myeloma

Premal Lulla, MBBS, Ifigeneia Tzannou, MD, George Carrum, MD, Carlos A. Ramos, MD, Rammurti Kamble, MD, Mrinalini Bilgi, Shivani Mukhi, Betty Chung, DO,MPH,MA, Ayumi Watanabe, Manik Kuvalekar, Adrian P. Gee, PhD, Bambi J. Grilley, RPh, Malcolm K. Brenner, MD PhD, Helen E. Heslop, MDDSc, Juan F. Vera, MD, Ann M. Leen, PhD

Blood (2018) 132 (Supplement 1): 1014.

https://doi.org/10.1182/blood-2018-99-113118

Published: 2018

Journal Articles

CD30-Chimeric Antigen Receptor (CAR) T Cells for Therapy of Hodgkin Lymphoma (HL)

Carlos A. Ramos, MD, Mrinalini Bilgi, Claudia P. Gerken, Olga Dakhova, Zhuyong Mei, Bambi J. Grilley, RPh, Adrian P. Gee, PhD, Cliona M. Rooney, PhD, Gianpietro Dotti, MD, Barbara Savoldo, MD PhD, Helen E. Heslop, MDDSc, Malcolm K. Brenner, MD PhD

Blood (2018) 132 (Supplement 1): 680.

https://doi.org/10.1182/blood-2018-99-111202

Published: 2018

Journal Articles

Targeting Lymphomas Using Non-Engineered, Multi-Antigen Specific T Cells

George Carrum, MD, Premal Lulla, MBBS, Ifigeneia Tzannou, MD, Ayumi Watanabe, Manik Kuvalekar, Mrinalini Bilgi, Rammurti Kamble, MD, Carlos A. Ramos, MD, Rayne Rouce, MD, Bambi J. Grilley, RPh, Adrian P. Gee, PhD, Malcolm K. Brenner, MD PhD, Helen E. Heslop, MDDSc, Cliona M. Rooney, PhD, Juan F. Vera, MD, Ann M. Leen, PhD

Blood (2018) 132 (Supplement 1): 1685.

https://doi.org/10.1182/blood-2018-99-113140

Published: 2018

Journal Articles

Adoptive Immunotherapy with Rapidly-Generated Multivirus-Specific T Cells Against AdV, EBV, CMV, HHV6 and BK after Allogeneic Hematopoietic Stem Cell Transplant

Blood (2017) 130 (Supplement 1): 4484.

https://doi.org/10.1182/blood.V130.Suppl_1.4484.4484

Published: 2017

Journal Articles

Safety and Efficacy of Adoptively Transferred Donor-Derived Tumor-Directed T Cells with Relapsed AML Post-Allogeneic HSCT

Premal Lulla, MBBS, Swati Naik, MBBS, Ifigeneia Tzannou, MD, Carlos A. Ramos, MD, Rammurti Kamble, MD, Catherine Robertson, Ayumi Watanabe, Manik Kuvalekar, Bambi J. Grilley, RPh, George Carrum, MD, Helen E. Heslop, MDDSc, Juan F. Vera, MD, Ann M. Leen, PhD

Blood (2017) 130 (Supplement 1): 164.

https://doi.org/10.1182/blood.V130.Suppl_1.164.164

Published: 2017

Journal Articles

Administration of Most Closely HLA-Matched Multivirus-Specific T Cells for the Treatment of EBV, CMV, AdV, HHV6, and BKV Post Allogeneic Hematopoietic Stem Cell Transplant

Ifigeneia Tzannou, MD, Anastasia Papadopoulou, PhD, Ayumi Watanabe, Manik Kuvalekar, Adrian P. Gee, PhD, Swati Naik, MD, Caridad Martinez, MD, Kathryn S. Leung, Ghadir S. Sasa, MD, Robert A. Krance, MD, George Carrum, MD, Carlos A. Ramos, MD, Bambi Grilley, Malcolm K. Brenner, MD PhD, Cliona M. Rooney, PhD, Helen E Heslop, MD DSc (Hon), Ann M. Leen, PhD, Bilal Omer, MD

Blood (2016) 128 (22): 501.

https://doi.org/10.1182/blood.V128.22.501.501

Published: 2016

Journal Articles

Rapidly-Generated EBV-Specific T Cells (EBVST-cells) to Treat Type 2 Latency Lymphoma

Rayne H. Rouce, MD, Birju Mehta, Sandhya Sharma, Serena Kimi Perna, MD, Benjamin Shin, Vicky Torrano, Fnu Spoorthi, Natalia Lapteva, PhD, Catherine M. Bollard, MD, Adrian P. Gee, PhD, Carlos A. Ramos, MD, Shannon Inman, Karen L. Hodgkin, Kurt C. Gunter, MD, Malcolm K. Brenner, MD PhD, Helen E. Heslop, MD, Cliona M. Rooney, PhD

Blood (2016) 128 (22): 2990.

https://doi.org/10.1182/blood.V128.22.2990.2990

Published: 2016

Journal Articles

Direct Comparison of In Vivo Fate of Second and Third-Generation CD19-Specific Chimeric Antigen Receptor (CAR)-T Cells in Patients with B-Cell Lymphoma: Reversal of Toxicity from Tonic Signaling

Diogo Gomes da Silva, Malini Mukherjee, Madhuwanti Srinivasan, Olga Dakhova, PhD, Hao Liu, PhD, Bambi Grilley, Adrian P. Gee, PhD, Sattva S. Neelapu, MD, Cliona M. Rooney, PhD, Helen E Heslop, MD DSc (Hon), Barbara Savoldo, MD PhD, Gianpietro Dotti, MD, Malcolm K. Brenner, MD PhD, Maksim Mamonkin, PhD, Carlos A. Ramos, MD

Blood (2016) 128 (22): 1851.

https://doi.org/10.1182/blood.V128.22.1851.1851

Published: 2016

Journal Articles

Safety of Multiple Doses of CAR T Cells

Rayne H. Rouce, MD, Kristen Fousek, Nabil Ahmed, MD, Stephen Gottschalk, MD, Barbara Savoldo, MD, Gianpietro Dotti, MD, Carlos A. Ramos, MD, Chrystal Louis, MD, Cliona M. Rooney, PhD, Malcolm K. Brenner, MD PhD, Helen E. Heslop, MD

Blood (2015) 126 (23): 4425.

https://doi.org/10.1182/blood.V126.23.4425.4425

Published: 2015

Journal Articles

Chimeric T Cells for Therapy of CD30+ Hodgkin and Non-Hodgkin Lymphomas

Carlos A. Ramos, MD, Brandon Ballard, BS, Enli Liu, MD MS, Olga Dakhova, PhD, Zhuyong Mei, MD, Hao Liu, PhD, Bambi Grilley, RPh, Cliona M. Rooney, PhD, Adrian P. Gee, PhD, Bill H. Chang, MD PhD, Catherine M. Bollard, MD, Malcolm K. Brenner, MD PhD, Gianpietro Dotti, MD, Helen E. Heslop, MD, Barbara Savoldo, MD PhD

Blood (2015) 126 (23): 185.

https://doi.org/10.1182/blood.V126.23.185.185

Published: 2015

Journal Articles

Immunotherapy for Lymphoma Using T Cells Targeting Multiple Tumor Associated Antigens

Ann Leen, PhD, Ifigeneia Tzannou, MD, Munu Bilgi, Hao Liu, PhD, Juan F Vera, MD, Ulrike Gerdemann, MD, Rammurti T Kamble, MD, Carlos A. Ramos, MD, Bambi Grilley, RPh, Adrian P. Gee, PhD, Catherine M. Bollard, MD, Malcolm K. Brenner, MD PhD, Helen E. Heslop, MD, Cliona M. Rooney, PhD, George Carrum, MD

Blood (2015) 126 (23): 186.

https://doi.org/10.1182/blood.V126.23.186.186

Published: 2015

Journal Articles

T Cells Expressing CD19-Specific Chimeric Antigen Receptors Are Inhibited By Indoleamine 2,3-Dioxygenase in Tumors

Soranobu Ninomiya, MD PhD, Leslie E Huye, PhD, Barbara Savoldo, MD PhD, Gianpietro Dotti, MD, Helen E. Heslop, MD, Malcolm K. Brenner, MD PhD, Cliona M Rooney, PhD, Carlos A. Ramos, MD

Blood (2014) 124 (21): 2434.

https://doi.org/10.1182/blood.V124.21.2434.2434

Published: 2014

Journal Articles

Infusion Of Donor-Derived CD19-Redirected-Virus-Specific T Cells For B-Cell Malignancies Relapsed After Allogeneic Stem Cell Transplant: A Phase I Study

Blood (2013) 122 (21): 152.

https://doi.org/10.1182/blood.V122.21.152.152

Published: 2013

NARROW

Level of Evidence for FDA Drug Approvals in Pivotal Clinical Trials of Hematological Malignancies

A Bank of CD30.CAR-Modified, Epstein-Barr Virus-Specific T Cells That Lacks Host Reactivity and Resists Graft Rejection for Patients with CD30-Positive Lymphoma

Treatment of Severe, Drug-Refractory Viral Infections with Allogeneic, Off-the-Shelf Multi-Virus Specific T Cells in Patients Following HSCT: Results from a Phase 2 Study

T Cell Immunity Toward Viral- and Tumor-Antigens Is Preserved in MDS Patients

Novel Immunotherapeutic Approaches for Hodgkin Lymphoma

Adoptive T-Cell Therapy for Acute Lymphoblastic Leukemia Targeting Multiple Tumor Associated Antigens

Rapid Generation of Multivirus-Specific T Lymphocytes for the Prevention and Treatment of Respiratory Viral Infections

Safety and Efficacy of Multiantigen-Targeted T Cells for Multiple Myeloma

CD30-Chimeric Antigen Receptor (CAR) T Cells for Therapy of Hodgkin Lymphoma (HL)

Targeting Lymphomas Using Non-Engineered, Multi-Antigen Specific T Cells

Adoptive Immunotherapy with Rapidly-Generated Multivirus-Specific T Cells Against AdV, EBV, CMV, HHV6 and BK after Allogeneic Hematopoietic Stem Cell Transplant

Safety and Efficacy of Adoptively Transferred Donor-Derived Tumor-Directed T Cells with Relapsed AML Post-Allogeneic HSCT

Administration of Most Closely HLA-Matched Multivirus-Specific T Cells for the Treatment of EBV, CMV, AdV, HHV6, and BKV Post Allogeneic Hematopoietic Stem Cell Transplant

Rapidly-Generated EBV-Specific T Cells (EBVST-cells) to Treat Type 2 Latency Lymphoma

Direct Comparison of In Vivo Fate of Second and Third-Generation CD19-Specific Chimeric Antigen Receptor (CAR)-T Cells in Patients with B-Cell Lymphoma: Reversal of Toxicity from Tonic Signaling

Safety of Multiple Doses of CAR T Cells

Chimeric T Cells for Therapy of CD30+ Hodgkin and Non-Hodgkin Lymphomas

Immunotherapy for Lymphoma Using T Cells Targeting Multiple Tumor Associated Antigens

T Cells Expressing CD19-Specific Chimeric Antigen Receptors Are Inhibited By Indoleamine 2,3-Dioxygenase in Tumors

Infusion Of Donor-Derived CD19-Redirected-Virus-Specific T Cells For B-Cell Malignancies Relapsed After Allogeneic Stem Cell Transplant: A Phase I Study

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American Society of Hematology

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American Society of Hematology

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