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Journal Articles

Lentiviral Hematopoietic Stem Cell Gene Therapy for Older Patients with X-Linked Severe Combined Immunodeficiency

Suk See De Ravin, MDPhD, Xiaolin Wu, Narda Theobald, Janet S Lee, John Gray, PhD, Imelda Celine Hanson, MD, Luigi Notarangelo, MDPhD, Brian P. Sorrentino, MD, Harry L. Malech, MD

Blood (2015) 126 (23): 261.

https://doi.org/10.1182/blood.V126.23.261.261

Published: 2015

Journal Articles

High Titer Lentivector from a Stable Lenti-Producer Efficiently Corrects CD34+ Hematopoietic Stem Cells from Patients with p47phox-Deficient Chronic Granulomatous Disease

Uimook Choi, PhD, Narda Theobald, Throm E Robert, PhD, John Gray, PhD, David J. Rawlings, MD, Brian P. Sorrentino, MD, Harry Malech, Suk See De Ravin, MD

Blood (2015) 126 (23): 2036.

https://doi.org/10.1182/blood.V126.23.2036.2036

Published: 2015

Journal Articles

Clonal Diversity Analysis Of Integrating Vector Transduced Hematopoietic Cells Using LAM-PCR Followed By Illumina-Based Next-Generation Sequencing Is Affected By False Positivity That Arises From Both Reaction Biochemistry and Bioinformatic Analysis

Michael R. Greene, MD, Michael Rusch, BA, Chunlao Tang, PhD, Jinghui Zhang, PhD, Brian P. Sorrentino, MD

Blood (2013) 122 (21): 1662.

https://doi.org/10.1182/blood.V122.21.1662.1662

Published: 2013

Journal Articles

N-Myc Is Overexpressed In Both Murine and Human Early T-Cell Precursor Leukemia and Is Sufficient To Initiate this Leukemia In Multipotent Primitive Arf -/- thymocytes

Louise M. Treanor, PhD, Sheng Zhou, PhD, Yu Fukuda, PhD, Nandakumar Satish, David Finkelstein, PhD, John D. Schuetz, PhD, Charles G. Mullighan, MBBS, MSc, MD, FRACP, FRCPA, Brian P. Sorrentino, MD

Blood (2013) 122 (21): 348.

https://doi.org/10.1182/blood.V122.21.348.348

Published: 2013

Journal Articles

Lmo2 Overexpression and Arf Loss Induce Myeloid Differentiation in Primitive Thymocytes

Louise M. Treanor, PhD, Sheng Zhou, PhD, Taihe Lu, PhD, Charles G Mullighan, MBBS, MD, FRACP, FRCPA, MSc, Brian P. Sorrentino, MD

Blood (2011) 118 (21): 47.

https://doi.org/10.1182/blood.V118.21.47.47

Published: 2011

Journal Articles

Transduction of Human CD34+ Derived NSG Repopulating Cells with An Insulated SIN Lentiviral Vector for SCID-X1 From a Stable Producer Cell Line At Clinical Scale

Michael R. Greene, MD, Timothy Lockey, PhD, John T. Gray, PhD, Paul W. Eldridge, PhD, Yoon-Sang Kim, MD, PhD, Perdeep K. Mehta, PhD, Brian P. Sorrentino, MD

Blood (2011) 118 (21): 670.

https://doi.org/10.1182/blood.V118.21.670.670

Published: 2011

Journal Articles

Gene Expression Profiling of Murine HOXB4-Transduced HSCs Shows Multiple Counter-Regulatory Signals That May Control HSC Pool Size

Hui Yu, Sheng Zhou, PhD, Geoffrey A. Neale, PhD, Brian P. Sorrentino, MD

Blood (2011) 118 (21): 2361.

https://doi.org/10.1182/blood.V118.21.2361.2361

Published: 2011

Journal Articles

Marking of Embryonic Precursors of Adult Hematopoietic Stem Cells At Gestational Day E7.5-E8.5 Using An Abcg2-CreER T2 Lineage Tracing Mouse Model

Sheng Zhou, PhD, Soghra Fatima, PhD, Brian P. Sorrentino, MD

Blood (2011) 118 (21): 1287.

https://doi.org/10.1182/blood.V118.21.1287.1287

Published: 2011

Journal Articles

Loss of p19 Arf Increases the Self-Renewal Capacity of Immature Thymocytes That Over-Express LMO2

Louise M. Treanor, PhD, Sheng Zhou, PhD, Taihe Lu, Brian P. Sorrentino, MD

Blood (2010) 116 (21): 4198.

https://doi.org/10.1182/blood.V116.21.4198.4198

Published: 2010

Journal Articles

Identifying Direct Targets of the Hoxb4 Transcription Factor Involved in Hematopoietic Cell Self Renewal.

Jie Jiang, MS, Yan Shou, PhD, Brian P. Sorrentino, MD

Blood (2006) 108 (11): 4190.

https://doi.org/10.1182/blood.V108.11.4190.4190

Published: 2006

Journal Articles

Lineage-Specific Expression of Mouse Abcg2 during Hematopoiesis Is Regulated by Alternative Use of Multiple Leader Exons and Promoters.

Yang Zong, MS, Sheng Zhou, PhD, Brian P. Sorrentino, MD

Blood (2005) 106 (11): 4251.

https://doi.org/10.1182/blood.V106.11.4251.4251

Published: 2005

Journal Articles

Relationship between ABCG2 Expression and Side Population Stem Cell Phenotype in Murine Hematopoietic System Revealed by an Abcg2/GFP Knock-In Mouse Model.

Mehrdad Tadjali, PhD, Sheng Zhou, PhD, Jerold Rehg, MD, Brian P. Sorrentino, MD

Blood (2005) 106 (11): 1716.

https://doi.org/10.1182/blood.V106.11.1716.1716

Published: 2005

Journal Articles

An Accelerated Incidence of T-Cell Malignancies in a Mouse Model of XSCID Gene Therapy Is Associated with an Expanded Progenitor Cell Pool in the Bone Marrow.

Yan Shou, PhD, Lilia Stepanova, Ph.D, Brian P. Sorrentino, MD

Blood (2005) 106 (11): 197.

https://doi.org/10.1182/blood.V106.11.197.197

Published: 2005

Journal Articles

Expression of a HoxC4 Retroviral Vector Mediates Expansion of Murine Hematopoietic Stem Cells with Normal Hematopoiesis in Transplanted Mice.

Lilia Stepanova, PhD, Brian P. Sorrentino, MD

Blood (2004) 104 (11): 2788.

https://doi.org/10.1182/blood.V104.11.2788.2788

Published: 2004

Journal Articles

ABCG2 Expression as Prospective Marker for Hematopoeitic Stem Cell Purification.

Mehrdad Tadjali, PhD, Sheng Zhou, PhD, Jerold Rehg, DVM, Brian P. Sorrentino, MD

Blood (2004) 104 (11): 3212.

https://doi.org/10.1182/blood.V104.11.3212.3212

Published: 2004

NARROW

Lentiviral Hematopoietic Stem Cell Gene Therapy for Older Patients with X-Linked Severe Combined Immunodeficiency

High Titer Lentivector from a Stable Lenti-Producer Efficiently Corrects CD34+ Hematopoietic Stem Cells from Patients with p47phox-Deficient Chronic Granulomatous Disease

Clonal Diversity Analysis Of Integrating Vector Transduced Hematopoietic Cells Using LAM-PCR Followed By Illumina-Based Next-Generation Sequencing Is Affected By False Positivity That Arises From Both Reaction Biochemistry and Bioinformatic Analysis

N-Myc Is Overexpressed In Both Murine and Human Early T-Cell Precursor Leukemia and Is Sufficient To Initiate this Leukemia In Multipotent Primitive Arf -/- thymocytes

Lmo2 Overexpression and Arf Loss Induce Myeloid Differentiation in Primitive Thymocytes

Transduction of Human CD34+ Derived NSG Repopulating Cells with An Insulated SIN Lentiviral Vector for SCID-X1 From a Stable Producer Cell Line At Clinical Scale

Gene Expression Profiling of Murine HOXB4-Transduced HSCs Shows Multiple Counter-Regulatory Signals That May Control HSC Pool Size

Marking of Embryonic Precursors of Adult Hematopoietic Stem Cells At Gestational Day E7.5-E8.5 Using An Abcg2-CreER T2 Lineage Tracing Mouse Model

Loss of p19 Arf Increases the Self-Renewal Capacity of Immature Thymocytes That Over-Express LMO2

Identifying Direct Targets of the Hoxb4 Transcription Factor Involved in Hematopoietic Cell Self Renewal.

Lineage-Specific Expression of Mouse Abcg2 during Hematopoiesis Is Regulated by Alternative Use of Multiple Leader Exons and Promoters.

Relationship between ABCG2 Expression and Side Population Stem Cell Phenotype in Murine Hematopoietic System Revealed by an Abcg2/GFP Knock-In Mouse Model.

An Accelerated Incidence of T-Cell Malignancies in a Mouse Model of XSCID Gene Therapy Is Associated with an Expanded Progenitor Cell Pool in the Bone Marrow.

Expression of a HoxC4 Retroviral Vector Mediates Expansion of Murine Hematopoietic Stem Cells with Normal Hematopoiesis in Transplanted Mice.

ABCG2 Expression as Prospective Marker for Hematopoeitic Stem Cell Purification.

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American Society of Hematology

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American Society of Hematology

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