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Bing CUi, PhD
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Journal Articles

Wnt5a Induces ROR1 to Complex with HS1, Which Undergoes Tyrosine Phosphorylation and Contributes to Planar-Cell-Polarity Migration in Chronic Lymphocytic Leukemia

Md Kamrul Hasan, PhD, Jian Yu, PhD, Liguang Chen, PhD, Bing Cui, PhD, Zhouxin Shen, PhD, George F. Widhopf, II, PhD, Laura Z. Rassenti, PhD, Steven P. Briggs, PhD, Thomas J. Kipps, MD, PhD
Journal: Blood
Blood (2016) 128 (22): 301.
https://doi.org/10.1182/blood.V128.22.301.301
Published: 2016
Journal Articles

Cirmtuzumab Targets ROR1 to Inhibit Ibrutinib-Resistant, Wnt5a-Induced Rac1 Activation in Chronic Lymphocytic Leukemia

Jian Yu, PhD, Liguang Chen, PhD, Bing Cui, PhD, Christina Wu, PhD, Michael Y. Choi, MD, Yun Chen, PhD, Ling Zhang, Laura Z. Rassenti, PhD, George F. Widhopf, II, PhD, Thomas J. Kipps, MD, PhD
Journal: Blood
Blood (2016) 128 (22): 2034.
https://doi.org/10.1182/blood.V128.22.2034.2034
Published: 2016
Journal Articles

Structural Features of ROR1 Required for Complexing with ROR2 and Enhancing Chemokine-Induced Migration and Leukemia-Cell Proliferation, Which Can be Blocked By the Anti-ROR1 Mab Cirmtuzumab (UC-961)

Jian Yu, PhD, Liguang Chen, MD PhD, George F. Widhopf, II, PhD, Suping Zhang, PhD, Bing Cui, PhD, Rongrong Wu, PhD, Ling Zhang, PhD, Thomas J. Kipps, MD, PhD
Journal: Blood
Blood (2015) 126 (23): 1741.
https://doi.org/10.1182/blood.V126.23.1741.1741
Published: 2015
Journal Articles

High-Level Expression of ROR1 Associates with Early Disease Progression in Patients with Chronic Lymphocytic Leukemia

Bing Cui, PhD, Liguang Chen, MD PhD, Laura Z. Rassenti, PhD, Emanuela M. Ghia, PhD, Jian Yu, PhD, Ling Zhang, PhD, Donna S Neuberg, ScD, William Wierda, MD PhD, Michael Keating, MBBS, Kanti R. Rai, MD, Neil E. Kay, MD, Jennifer R. Brown, MD PhD, John C. Byrd, MD, John Gribben, MDDSc, Thomas J. Kipps, MD, PhD
Journal: Blood
Blood (2015) 126 (23): 1713.
https://doi.org/10.1182/blood.V126.23.1713.1713
Published: 2015
Journal Articles

ROR1 Negative Chronic Lymphocytic Leukemia (CLL) Have a Distinctive Gene Expression Signature and May Represent an Indolent-Disease Subtype

Emanuela M. Ghia, PhD, Laura Z. Rassenti, PhD, Liguang Chen, MD PhD, Bing Cui, PhD, Christopher Deboever, BS, Kelly A. Frazer, Thomas J. Kipps, MD, PhD
Journal: Blood
Blood (2015) 126 (23): 2932.
https://doi.org/10.1182/blood.V126.23.2932.2932
Published: 2015
Journal Articles

Mir-155 Contributed to Chronic Lymphocytic Leukemia Survival by Modulation of BCR-Signalling

Liguang Chen, MD, PhD, Bing Cui, PhD, George Chen, B.S., Michelle Salcedo, BS, Carlo M. Croce, MD, Thomas J. Kipps, M.D., Ph.D
Journal: Blood
Blood (2011) 118 (21): 620.
https://doi.org/10.1182/blood.V118.21.620.620
Published: 2011
Journal Articles

A Monoclonal Antibody Specifically Targeting CD44 Inhibits B-Cell Chronic Lymphocytic Leukemia Cell Survival In Vitro and In Vivo

Suping Zhang, PhD, Christina C.N. Wu, Ph.D., Jessie-Farah Fecteau, Ph.D., Bing Cui, PhD, Rongrong Wu, Laura Z. Rassenti, Ph.D., Fitzgerald S. Lao, B.S., Rommel Tawatao, B.S., Stefan Weigland, PhD, Charles Prussak, PhD, Dennis A. Carson, MD, Thomas J. Kipps, M.D., Ph.D
Journal: Blood
Blood (2011) 118 (21): 927.
https://doi.org/10.1182/blood.V118.21.927.927
Published: 2011
Journal Articles

Targeting of Chronic Lymphocytic Leukemia B Cells with a Novel Monoclonal Antibody to ROR1

Bing CUi, PhD, George F. Widhopf, II, PhD, Jian Yu, PhD, Daniel Martinez, BS, Esther Avery, B.S., Suping Zhang, PhD, Liguang Chen, MD, PhD, Rongrong Wu, Christina C.N. Wu, Ph.D., Charles Prussak, PhD, Thomas J. Kipps, M.D., Ph.D
Journal: Blood
Blood (2011) 118 (21): 984.
https://doi.org/10.1182/blood.V118.21.984.984
Published: 2011
Journal Articles

In Vitro Propagation of Mesenchymal Stromal Cells From Marrow Aspirates of Patients with Chronic Lymphocytic Leukemia Is Dependent Upon Physiologic Oxygen Tension

Jessie-Farah Fecteau, Ph.D., Davorka Messmer, PhD, Suping Zhang, PhD, Bing Cui, PhD, Liguang Chen, MD, PhD, Thomas J. Kipps, M.D., Ph.D
Journal: Blood
Blood (2011) 118 (21): 2839.
https://doi.org/10.1182/blood.V118.21.2839.2839
Published: 2011
Journal Articles

Influence of Mir-155 On B-Cell Receptor Signaling in Chronic Lymphocytic Leukemia.

Liguang Chen, MD, PhD, Bing Cui, PhD, George Chen, Michelle Salcedo, Carlo M. Croce, MD, Thomas J. Kipps, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 2343.
https://doi.org/10.1182/blood.V114.22.2343.2343
Published: 2009
Journal Articles

Association Between the Proficiency of B-Cell Receptor Signaling and the Relative Expression Levels of ZAP-70, SHIP-1, and Mir-155 in Chronic Lymphocytic Leukemia

Liguang Chen, MD, PhD, Bing Cui, PhD, Suping Zhang, PhD, George Chen, Carlo M. Croce, MD, Thomas J. Kipps, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 3155.
https://doi.org/10.1182/blood.V112.11.3155.3155
Published: 2008