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Journal Articles

Safety and Antitumor Effects of CD19-Specific Autologous Chimeric Antigen Receptor-Modified T (CAR-T) Cells Expressing the Inducible Caspase 9 Safety Switch (iC9-CAR19 T Cells) in Adult Acute Lymphoblastic Leukemia (ALL)

Matthew C Foster, MD, Philip A. Roehrs, MD, George E Hucks, MD, Natalie S Grover, MD, Paul M. Armistead, MD PhD, Katarzyna Jamieson, MD, Faith Brianne Buchanan, PA, J. Kaitlin C Morrison, PhD, Spencer Laing, BA, Catherine Joyce Arago Cheng, BS, Jonathan S. Serody, MD, Gianpietro Dotti, MD, Barbara Savoldo, MD PhD

Blood (2020) 136 (Supplement 1): 36–37.

https://doi.org/10.1182/blood-2020-139051

Published: 2020

Journal Articles

Novel Immunotherapeutic Approaches for Hodgkin Lymphoma

Barbara Savoldo, MD PhD, Natalie S Grover, MD, Carlos A. Ramos, MD, Gianpietro Dotti, MD

Blood (2019) 134 (Supplement_1): SCI-9.

https://doi.org/10.1182/blood-2019-121075

Published: 2019

Journal Articles

Retrospective Cohort Study Analyzing the Safety and Efficacy of Anti-PD-1 Therapy Following CD30 CAR-T Cell Therapy in Relapsed/Refractory Hodgkin Lymphoma

Timothy J Voorhees, MD, Natalie S Grover, MD, Anne Beaven, MD, Steven I Park, MD, J. Kaitlin Morrison, PhD, Catherine Joyce Arago Cheng, BS, Spencer Laing, BA, Gianpietro Dotti, MD, Barbara Savoldo, MD PhD, Jonathan S Serody, MD

Blood (2019) 134 (Supplement_1): 3233.

https://doi.org/10.1182/blood-2019-122846

Published: 2019

Journal Articles

Pre-Clinical Evaluation of B7-H3-Specific Chimeric Antigen Receptor T-Cells for the Treatment of Acute Myeloid Leukemia

Eben Lichtman, MD, Hongwei Du, PhD, Barbara Savoldo, MD PhD, Soldano Ferrone, MD PhD, Guangming Li, PhD, Lishan Su, PhD, Gianpietro Dotti, MD

Blood (2018) 132 (Supplement 1): 701.

https://doi.org/10.1182/blood-2018-99-113468

Published: 2018

Journal Articles

Clinical Responses to CAR.CD30-T Cells in Patients with CD30+ Lymphomas Relapsed after Multiple Treatments Including Brentuximab Vedotin

Blood (2018) 132 (Supplement 1): 681.

https://doi.org/10.1182/blood-2018-99-113534

Published: 2018

Journal Articles

CD30-Chimeric Antigen Receptor (CAR) T Cells for Therapy of Hodgkin Lymphoma (HL)

Carlos A. Ramos, MD, Mrinalini Bilgi, Claudia P. Gerken, Olga Dakhova, Zhuyong Mei, Bambi J. Grilley, RPh, Adrian P. Gee, PhD, Cliona M. Rooney, PhD, Gianpietro Dotti, MD, Barbara Savoldo, MD PhD, Helen E. Heslop, MDDSc, Malcolm K. Brenner, MD PhD

Blood (2018) 132 (Supplement 1): 680.

https://doi.org/10.1182/blood-2018-99-111202

Published: 2018

Journal Articles

Direct Comparison of In Vivo Fate of Second and Third-Generation CD19-Specific Chimeric Antigen Receptor (CAR)-T Cells in Patients with B-Cell Lymphoma: Reversal of Toxicity from Tonic Signaling

Diogo Gomes da Silva, Malini Mukherjee, Madhuwanti Srinivasan, Olga Dakhova, PhD, Hao Liu, PhD, Bambi Grilley, Adrian P. Gee, PhD, Sattva S. Neelapu, MD, Cliona M. Rooney, PhD, Helen E Heslop, MD DSc (Hon), Barbara Savoldo, MD PhD, Gianpietro Dotti, MD, Malcolm K. Brenner, MD PhD, Maksim Mamonkin, PhD, Carlos A. Ramos, MD

Blood (2016) 128 (22): 1851.

https://doi.org/10.1182/blood.V128.22.1851.1851

Published: 2016

Journal Articles

Cord Blood Derived Natural Killer Cells Engineered with a Chimeric Antigen Receptor Targeting CD19 and Expressing IL-15 Have Long Term Persistence and Exert Potent Anti-Leukemia Activity

Enli Liu, MD MS, Yijiu Tong, Gianpietro Dotti, MD, Barbara Savoldo, MD, Muharrem Muftuoglu, Kayo Kondo, PhD, Malini Mukherjee, Jordan S. Orange, MD PhD, Catherine Sobieski, Abdullah Alsuliman, Hila Shaim, MD, Nobuhiko Imahashi, MD PhD, Michael J. Keating, MD, Chitra M. Hosing, MD, Nina Shah, MD, William Wierda, MD PhD, Richard Champlin, MD, Elizabeth J. Shpall, MD, Katayoun Rezvani, MDPhD

Blood (2015) 126 (23): 3091.

https://doi.org/10.1182/blood.V126.23.3091.3091

Published: 2015

Journal Articles

Safety of Multiple Doses of CAR T Cells

Rayne H. Rouce, MD, Kristen Fousek, Nabil Ahmed, MD, Stephen Gottschalk, MD, Barbara Savoldo, MD, Gianpietro Dotti, MD, Carlos A. Ramos, MD, Chrystal Louis, MD, Cliona M. Rooney, PhD, Malcolm K. Brenner, MD PhD, Helen E. Heslop, MD

Blood (2015) 126 (23): 4425.

https://doi.org/10.1182/blood.V126.23.4425.4425

Published: 2015

Journal Articles

Third Generation CD19-CAR T Cells for Relapsed and Refractory Lymphoma and Leukemia Report from the Swedish Phase I/IIa Trial

Gunilla Enblad, MDPhD, Hannah Karlsson, PhD, Kristina Wikstrom, PhD, Magnus Essand, PhD, Barbara Savoldo, MD PhD, Malcolm K. Brenner, MD PhD, Gianpietro Dotti, MD, Helene Hallbook, MDPhD, Martin Hoglund, MD PhD, Hans Hagberg, MD PhD, Angelica Loskog, PhD

Blood (2015) 126 (23): 1534.

https://doi.org/10.1182/blood.V126.23.1534.1534

Published: 2015

Journal Articles

Chimeric T Cells for Therapy of CD30+ Hodgkin and Non-Hodgkin Lymphomas

Carlos A. Ramos, MD, Brandon Ballard, BS, Enli Liu, MD MS, Olga Dakhova, PhD, Zhuyong Mei, MD, Hao Liu, PhD, Bambi Grilley, RPh, Cliona M. Rooney, PhD, Adrian P. Gee, PhD, Bill H. Chang, MD PhD, Catherine M. Bollard, MD, Malcolm K. Brenner, MD PhD, Gianpietro Dotti, MD, Helen E. Heslop, MD, Barbara Savoldo, MD PhD

Blood (2015) 126 (23): 185.

https://doi.org/10.1182/blood.V126.23.185.185

Published: 2015

Journal Articles

T Cells Expressing CD19-Specific Chimeric Antigen Receptors Are Inhibited By Indoleamine 2,3-Dioxygenase in Tumors

Soranobu Ninomiya, MD PhD, Leslie E Huye, PhD, Barbara Savoldo, MD PhD, Gianpietro Dotti, MD, Helen E. Heslop, MD, Malcolm K. Brenner, MD PhD, Cliona M Rooney, PhD, Carlos A. Ramos, MD

Blood (2014) 124 (21): 2434.

https://doi.org/10.1182/blood.V124.21.2434.2434

Published: 2014

Journal Articles

Comparison of Free Light Chain Assay with Protein Electrophoresis for Screening and Monitoring PTLD

Deborah Kuhn, PhD, Ping Wang, PhD, Irene Shu, PhD, Jie Xuan, PhD, Zheng Cao, PhD, Barbara Savoldo, MD PhD

Blood (2014) 124 (21): 5883.

https://doi.org/10.1182/blood.V124.21.5883.5883

Published: 2014

Journal Articles

Boosting In Vivo CAR-Redirected Virus-Specific CTLs With Universal-Artificial Antigen Presenting Cells

Ignazio Caruana, Gerrit Weber, MD, Barbara Savoldo, MD, Gianpietro Dotti, MD

Blood (2013) 122 (21): 4204.

https://doi.org/10.1182/blood.V122.21.4204.4204

Published: 2013

Journal Articles

Infusion Of Donor-Derived CD19-Redirected-Virus-Specific T Cells For B-Cell Malignancies Relapsed After Allogeneic Stem Cell Transplant: A Phase I Study

Blood (2013) 122 (21): 152.

https://doi.org/10.1182/blood.V122.21.152.152

Published: 2013

Journal Articles

A “non-fratricidal” αβ- T Cell Receptor That Targets Survivin Expressed By Hematological Malignancies

Caroline Arber, MD, Xiang Feng, BS, Harshal Abhyankar, MS, Helen E. Heslop, MD, Malcolm K. Brenner, MD, PhD, Patrick Barth, PhD, Gianpietro Dotti, MD, Barbara Savoldo, MD, PhD

Blood (2013) 122 (21): 141.

https://doi.org/10.1182/blood.V122.21.141.141

Published: 2013

Journal Articles

Clinical Responses In Patients Infused With T Lymphocytes Redirected To Target κ-Light Immunoglobulin Chain

Carlos A. Ramos, MD, Barbara Savoldo, MD, PhD, Enli Liu, MD, MS, Adrian P. Gee, PhD, Zhuyong Mei, MD, Bambi J. Grilley, RPh, Cliona M. Rooney, PhD, Helen E. Heslop, MD, Malcolm K. Brenner, MD, PhD, Gianpietro Dotti, MD

Blood (2013) 122 (21): 506.

https://doi.org/10.1182/blood.V122.21.506.506

Published: 2013

Journal Articles

Co-Expression of a Suicide Gene in CAR-Redirected T Cells Enables the Safe Targeting of CD44v6 for Leukemia and Myeloma Eradication

Monica Casucci, PhD, Benedetta Nicolis di Robilant, MSc, Laura Falcone, MSc, Barbara Camisa, BSc, Pietro Genovese, PhD, Bernhard Gentner, MD $, Luigi Naldini, MD, PhD, Barbara Savoldo, MD, PhD, Fabio Ciceri, MD, Claudio Bordignon, MD, Gianpietro Dotti, MD, Chiara Bonini, MD, Attilio Bondanza, MD, PhD

Blood (2012) 120 (21): 949.

https://doi.org/10.1182/blood.V120.21.949.949

Published: 2012

Journal Articles

Improving Immune Reconstitution After Cord Blood Transplantation Using Ex Vivo Expanded Virus-Specific T Cells: A Phase I Clinical Study

Patrick J Hanley, PhD, Caridad Martinez, MD, Kathryn Leung, MD, Barbara Savoldo, MD, PhD, Gianpietro Dotti, MD, Malcolm K. Brenner, MB, PhD, FRCP, FRCPath, Cliona M. Rooney, PhD, Helen E. Heslop, MD, Robert A. Krance, MD, Elizabeth J Shpall, MD, Catherine M. Bollard, MD, FRACP, FRCPA

Blood (2012) 120 (21): 224.

https://doi.org/10.1182/blood.V120.21.224.224

Published: 2012

Journal Articles

Human Papillomavirus Type 16 (HPV16) E6/E7-Specific Cytotoxic T Lymphocytes (CTLs) for Immunotherapy of HPV-Associated Malignancies

Carlos A. Ramos, MD, Neeharika Narala, MSc, Ann M. Leen, PhD, Ulrike Gerdemann, MD, Matthew L. Anderson, MD, PhD, Erich M. Sturgis, MD, MPH, Barbara Savoldo, MD, PhD, Helen E. Heslop, MD, Malcolm K. Brenner, MD, PhD, Cliona M. Rooney, PhD

Blood (2011) 118 (21): 1913.

https://doi.org/10.1182/blood.V118.21.1913.1913

Published: 2011

NARROW

Safety and Antitumor Effects of CD19-Specific Autologous Chimeric Antigen Receptor-Modified T (CAR-T) Cells Expressing the Inducible Caspase 9 Safety Switch (iC9-CAR19 T Cells) in Adult Acute Lymphoblastic Leukemia (ALL)

Novel Immunotherapeutic Approaches for Hodgkin Lymphoma

Retrospective Cohort Study Analyzing the Safety and Efficacy of Anti-PD-1 Therapy Following CD30 CAR-T Cell Therapy in Relapsed/Refractory Hodgkin Lymphoma

Pre-Clinical Evaluation of B7-H3-Specific Chimeric Antigen Receptor T-Cells for the Treatment of Acute Myeloid Leukemia

Clinical Responses to CAR.CD30-T Cells in Patients with CD30+ Lymphomas Relapsed after Multiple Treatments Including Brentuximab Vedotin

CD30-Chimeric Antigen Receptor (CAR) T Cells for Therapy of Hodgkin Lymphoma (HL)

Direct Comparison of In Vivo Fate of Second and Third-Generation CD19-Specific Chimeric Antigen Receptor (CAR)-T Cells in Patients with B-Cell Lymphoma: Reversal of Toxicity from Tonic Signaling

Cord Blood Derived Natural Killer Cells Engineered with a Chimeric Antigen Receptor Targeting CD19 and Expressing IL-15 Have Long Term Persistence and Exert Potent Anti-Leukemia Activity

Safety of Multiple Doses of CAR T Cells

Third Generation CD19-CAR T Cells for Relapsed and Refractory Lymphoma and Leukemia Report from the Swedish Phase I/IIa Trial

Chimeric T Cells for Therapy of CD30+ Hodgkin and Non-Hodgkin Lymphomas

T Cells Expressing CD19-Specific Chimeric Antigen Receptors Are Inhibited By Indoleamine 2,3-Dioxygenase in Tumors

Comparison of Free Light Chain Assay with Protein Electrophoresis for Screening and Monitoring PTLD

Boosting In Vivo CAR-Redirected Virus-Specific CTLs With Universal-Artificial Antigen Presenting Cells

Infusion Of Donor-Derived CD19-Redirected-Virus-Specific T Cells For B-Cell Malignancies Relapsed After Allogeneic Stem Cell Transplant: A Phase I Study

A “non-fratricidal” αβ- T Cell Receptor That Targets Survivin Expressed By Hematological Malignancies

Clinical Responses In Patients Infused With T Lymphocytes Redirected To Target κ-Light Immunoglobulin Chain

Co-Expression of a Suicide Gene in CAR-Redirected T Cells Enables the Safe Targeting of CD44v6 for Leukemia and Myeloma Eradication

Improving Immune Reconstitution After Cord Blood Transplantation Using Ex Vivo Expanded Virus-Specific T Cells: A Phase I Clinical Study

Human Papillomavirus Type 16 (HPV16) E6/E7-Specific Cytotoxic T Lymphocytes (CTLs) for Immunotherapy of HPV-Associated Malignancies

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American Society of Hematology

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American Society of Hematology

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