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Archibald S Perkins, MD PhD
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Journal Articles

MDS1-EVI1 Complex (MECOM) Activation Promotes Leukemic Stem Cell Quiescence By Upregulating CDKN1C/P57 Kip2

Edward Ayoub, PhD MS, BSc, Yi Zhang, PhD, Michael Andreeff, MD PhD, Archibald S. Perkins, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 6–7.
https://doi.org/10.1182/blood-2020-143313
Published: 2020
Journal Articles

Modeling Defective Erythropoiesis in Myelodysplastic Syndrome (MDS)

Kathleen E. McGrath, PhD, Seana C Catherman, BS, Katherine H Fegan, MS, Anne D Koniski, MS, Allison J. Li, MS, Benjamin J. Frisch, PhD, Rhonda J. Staversky, BS, Michael Wilson, PhD, Yi Zhang, PhD, Michael W. Becker, MD, Archibald S Perkins, MD PhD, Laura M. Calvi, MD, James Palis, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4234.
https://doi.org/10.1182/blood.V130.Suppl_1.4234.4234
Published: 2017
Journal Articles

Aging of Hematopoietic Stem Cells Is Driven By Regional Specialization of Marrow Macrophages

Corey M Hoffman, MS, Sarah E Latchney, PhD, Mark LaMere, BA, Jason R Myers, MS, John M Ashton, PhD, Allison J. Li, MS, Frank Akwaa, MD, Rakhil Rubinova, D.O., Amanda McCabe, PhD, Julianne N. Smith, PhD, Jane L. Liesveld, MD, Benjamin J. Frisch, PhD, Michael Rusty Elliott, PhD, Katherine C MacNamara, PhD, Michael W. Becker, MD, James Palis, MD, Archibald S. Perkins, MD PhD, Laura M. Calvi, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 95.
https://doi.org/10.1182/blood.V130.Suppl_1.95.95
Published: 2017
Journal Articles

Novel In Vivo Models Uncover Non-Cell-Autonomous Effects of Myelodysplastic Syndrome (MDS) on Marrow Osteolineage Cells and Hematopoietic Dysfunction

Allison J. Li, MS, Benjamin J. Frisch, PhD, Mark LaMere, BA, Rhonda J. Staversky, BS, Daniel Byun, BS, Edward Ayoub, MS, Jane L. Liesveld, MD, James Palis, MD, Archibald S. Perkins, MD PhD, Michael W. Becker, MD, Laura M. Calvi, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1681.
https://doi.org/10.1182/blood.V130.Suppl_1.1681.1681
Published: 2017
Journal Articles

High-Level EVI1 Perturbs Hematopoietic Function By Skewing Cells Towards Myeloid Phenotype Via Induction of PU.1/ Spi1 Â Transcription

Archibald S Perkins, MD PhD, Michael Wilson, PhD, Edward Ayoub, MS, Yi Zhang, PhD, McGrath E Kathleen, PhD, James Palis, MD, Allison J. Li, MS, Laura M. Calvi, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2505.
https://doi.org/10.1182/blood.V130.Suppl_1.2505.2505
Published: 2017
Journal Articles

Targeting the Creatine Kinase Pathway in EVI1-Positive Acute Myeloid Leukemia

Alexandre Puissant, PhD, Nina Fenouille, PhD, Christopher F. Bassil, BA, Issam Ben-Sahra, PhD, Lina Benajiba, Gabriela Alexe, PhD, Azucena Ramos, Yana Pikman, MD, Michael R. Burgess, MD PhD, Qing Li, MD PhD, Frederic Luciano, PhD, Patrick Auberger, PhD, Ilene Galinsky, MSN, ANPc, Daniel J. DeAngelo, MD PhD, Richard M. Stone, MD, Archibald S. Perkins, MD PhD, Kevin Shannon, MD, Michael T. Hemann, PhD, Kimberly Stegmaier, MD
Journal: Blood
Blood (2016) 128 (22): 523.
https://doi.org/10.1182/blood.V128.22.523.523
Published: 2016
Journal Articles

EVI1, A Potential Regulator Of CEBPA ; A Contributory Mechanism In Leukemogenesis?

Michael Wilson, MS, Yi Zhang, Ph.D., Xiaohui Cui, Charles A. Wuertzer, PhD, Archibald S. Perkins, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 2495.
https://doi.org/10.1182/blood.V122.21.2495.2495
Published: 2013
Journal Articles

Serum Response Factor Is An Essential Transcription Factor in Megakaryocytic Maturation.

Stephanie Halene, MD, Yuan Gao, Ph.D., Katherine Hahn, Ph.D., Elenoe Smith, Sharon Lin, Archibald S. Perkins, MD, PhD, Diane Krause, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 3652.
https://doi.org/10.1182/blood.V114.22.3652.3652
Published: 2009
Journal Articles

Development of a Novel Polyamide-Based Agent to Inhibit EVI1 Function

Géraldine Sicot, Marion Vogel, Yi Zhang, Daniel A Harki, Ph.D., Kimberly Lezon-Geyda, Ph.D., Peter Dervan, Archibald S. Perkins, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 2660.
https://doi.org/10.1182/blood.V112.11.2660.2660
Published: 2008
Journal Articles

EVI1 Blocks Apoptosis in DA-1 Myeloid Leukemia Cells Via Enhanced Transcription of the Prosurvival Gene Bcl2a1 (A1)

Archibald S. Perkins, MD, PhD, Jacob J. del Campo, Ph.D., Ying-Yi Xiao, PhD, Yi Zhang, Ph.D., Sharon J. Lin, Ph.D., Jonathan Dudley, David Tuck, Bogdan Yatsula, Ph.D.
Journal: Blood
Blood (2008) 112 (11): 3805.
https://doi.org/10.1182/blood.V112.11.3805.3805
Published: 2008
Journal Articles

Analysis of a LacZ Knock-In Allele of MDS1 Indicates a Critical Role in Hematopoietic Development.

Archibald S. Perkins, MD, PhD, Sharon Lin, Jacob delCampo, Ph.D., Fernando Camargo, Ph.D., Kimberly Lezon-Geyda, Ph.D.
Journal: Blood
Blood (2006) 108 (11): 444.
https://doi.org/10.1182/blood.V108.11.444.444
Published: 2006
Journal Articles

Role of EVI1 in Cell Cycle Regulation: Relevance of Specific Target Genes.

Archibald S. Perkins, MD, PhD, Ying-Yi Xiao, PhD, Kimberly Lezon-Geyda, PhD, Sharon Lin, Fernando Camargo, PhD, David Tuck, MD, Bogdan Yatsula, PhD
Journal: Blood
Blood (2005) 106 (11): 1614.
https://doi.org/10.1182/blood.V106.11.1614.1614
Published: 2005