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Journal Articles

Treatment of Severe, Drug-Refractory Viral Infections with Allogeneic, Off-the-Shelf Multi-Virus Specific T Cells in Patients Following HSCT: Results from a Phase 2 Study

Ifigeneia Tzannou, MD, Ayumi Watanabe, Bsc, Anastasia Papadopoulou, PhD, Manik Kuvalekar, Msc, Swati Naik, MBBS, Premal Lulla, MBBS, Robert A. Krance, MD, Carlos A. Ramos, MD, Helen E. Heslop, MD DSc, Ann M. Leen, PhD, Bilal Omer, MD

Blood (2020) 136 (Supplement 1): 2–3.

https://doi.org/10.1182/blood-2020-143037

Published: 2020

Journal Articles

Using Allogeneic, Off-the-Shelf, Sars-Cov-2-Specific T Cells to Treat High Risk Patients with COVID-19

Spyridoula Vasileiou, PhD, Manik Kuvalekar, Msc, Aster Workineh, Msc, Ayumi Watanabe, Bsc, Yovana Velazquez, Bsc, Suhasini Lulla, Bsc, Helen E. Heslop, MD DSc, Kimberly Mooney, Bsc, Kevin Grimes, MD, George Carrum, MD, LaQuisa C. Hill, MD, Premal Lulla, MBBS, Ann M. Leen, PhD

Blood (2020) 136 (Supplement 1): 5.

https://doi.org/10.1182/blood-2020-140490

Published: 2020

Journal Articles

T Cell Immunity Toward Viral- and Tumor-Antigens Is Preserved in MDS Patients

Hussein Hamad, MD, Wingchi K Leung, MD, Spyridoula Vasileiou, PhD, Shivani Mukhi, Quillan Huang, MD, George Carrum, MD, Carlos A. Ramos, MD, Rammurti Kamble, MD, LaQuisa C. Hill, MD, Ann M. Leen, PhD, Premal Lulla, MBBS

Blood (2019) 134 (Supplement_1): 4225.

https://doi.org/10.1182/blood-2019-126792

Published: 2019

Journal Articles

Targeting Lymphomas Using Non-Engineered, Multi-Antigen Specific T Cells

George Carrum, MD, Premal Lulla, MBBS, Ifigeneia Tzannou, MD, Ayumi Watanabe, Manik Kuvalekar, Mrinalini Bilgi, Rammurti Kamble, MD, Carlos A. Ramos, MD, Rayne Rouce, MD, Bambi J. Grilley, RPh, Adrian P. Gee, PhD, Malcolm K. Brenner, MD PhD, Helen E. Heslop, MDDSc, Cliona M. Rooney, PhD, Juan F. Vera, MD, Ann M. Leen, PhD

Blood (2018) 132 (Supplement 1): 1685.

https://doi.org/10.1182/blood-2018-99-113140

Published: 2018

Journal Articles

Myd88/CD40 Costimulation to Enhance the Antitumor Activity of CD123-ENG T-Cells for the Immunotherapy of AML

Erin Doherty, MD, Abishek Vaidya, MS, Xiya Wu, Challice L. Bonifant, MD PhD, Melinda Mata, PhD, Ann M. Leen, PhD, Stephen Gottschalk, MD, Mireya P. Velasquez, MD

Blood (2018) 132 (Supplement 1): 4075.

https://doi.org/10.1182/blood-2018-99-116817

Published: 2018

Journal Articles

Adoptive T-Cell Therapy for Acute Lymphoblastic Leukemia Targeting Multiple Tumor Associated Antigens

Swati Naik, MBBS, Premal Lulla, MBBS, Ifigeneia Tzannou, MD, Robert A. Krance, MD, George Carrum, MD, Rammurti Kamble, MD, Carlos A. Ramos, MD, Catherine Robertson, Manik Kuvalekar, Ayumi Watanabe, Bambi J. Grilley, RPh, Juan F. Vera, MD, Helen E. Heslop, MDDSc, Ann M. Leen, PhD

Blood (2018) 132 (Supplement 1): 2693.

https://doi.org/10.1182/blood-2018-99-115465

Published: 2018

Journal Articles

Safety and Efficacy of Multiantigen-Targeted T Cells for Multiple Myeloma

Premal Lulla, MBBS, Ifigeneia Tzannou, MD, George Carrum, MD, Carlos A. Ramos, MD, Rammurti Kamble, MD, Mrinalini Bilgi, Shivani Mukhi, Betty Chung, DO,MPH,MA, Ayumi Watanabe, Manik Kuvalekar, Adrian P. Gee, PhD, Bambi J. Grilley, RPh, Malcolm K. Brenner, MD PhD, Helen E. Heslop, MDDSc, Juan F. Vera, MD, Ann M. Leen, PhD

Blood (2018) 132 (Supplement 1): 1014.

https://doi.org/10.1182/blood-2018-99-113118

Published: 2018

Journal Articles

Towards Functional Immune Monitoring in Allogeneic Hematopoietic Stem Cell Transpant Recipients

Swati Naik, MBBS, Paibel I. Aguayo-Hiraldo, MD, Spyridoula Vasileiou, PhD, Shivani Mukhi, Aster Workineh, Robert A. Krance, MD, Stephen Gottschalk, MD, Ann M. Leen, PhD

Blood (2017) 130 (Supplement 1): 3258.

https://doi.org/10.1182/blood.V130.Suppl_1.3258.3258

Published: 2017

Journal Articles

Adoptive Immunotherapy with Rapidly-Generated Multivirus-Specific T Cells Against AdV, EBV, CMV, HHV6 and BK after Allogeneic Hematopoietic Stem Cell Transplant

Blood (2017) 130 (Supplement 1): 4484.

https://doi.org/10.1182/blood.V130.Suppl_1.4484.4484

Published: 2017

Journal Articles

Evaluating Cyclin A1 As an Immunotherapeutic Target in Acute Myeloid Leukemia (AML)

Premal Lulla, MBBS, Ifigeneia Tzannou, MD, Daniel Brenner, Helen E. Heslop, MDDSc, Juan F. Vera, MD, Ann M. Leen, PhD

Blood (2017) 130 (Supplement 1): 1907.

https://doi.org/10.1182/blood.V130.Suppl_1.1907.1907

Published: 2017

Journal Articles

Safety and Efficacy of Adoptively Transferred Donor-Derived Tumor-Directed T Cells with Relapsed AML Post-Allogeneic HSCT

Premal Lulla, MBBS, Swati Naik, MBBS, Ifigeneia Tzannou, MD, Carlos A. Ramos, MD, Rammurti Kamble, MD, Catherine Robertson, Ayumi Watanabe, Manik Kuvalekar, Bambi J. Grilley, RPh, George Carrum, MD, Helen E. Heslop, MDDSc, Juan F. Vera, MD, Ann M. Leen, PhD

Blood (2017) 130 (Supplement 1): 164.

https://doi.org/10.1182/blood.V130.Suppl_1.164.164

Published: 2017

Journal Articles

Safety and Preliminary Efficacy of "Ready to Administer" Cytomegalovirus (CMV)-Specific T Cells for the Treatment of Patients with Refractory CMV Infection

Ifigeneia Tzannou, MD, Kathryn S. Leung, Caridad Martinez, MD, Swati Naik, MD, Stephen Gottschalk, MD, Adrian P. Gee, PhD, Bambi Grilley, Ayumi Watanabe, Ann M. Leen, PhD, Sunitha Kakarla, PhD, Bilal Omer, MD

Blood (2016) 128 (22): 388.

https://doi.org/10.1182/blood.V128.22.388.388

Published: 2016

Journal Articles

Administration of Most Closely HLA-Matched Multivirus-Specific T Cells for the Treatment of EBV, CMV, AdV, HHV6, and BKV Post Allogeneic Hematopoietic Stem Cell Transplant

Ifigeneia Tzannou, MD, Anastasia Papadopoulou, PhD, Ayumi Watanabe, Manik Kuvalekar, Adrian P. Gee, PhD, Swati Naik, MD, Caridad Martinez, MD, Kathryn S. Leung, Ghadir S. Sasa, MD, Robert A. Krance, MD, George Carrum, MD, Carlos A. Ramos, MD, Bambi Grilley, Malcolm K. Brenner, MD PhD, Cliona M. Rooney, PhD, Helen E Heslop, MD DSc (Hon), Ann M. Leen, PhD, Bilal Omer, MD

Blood (2016) 128 (22): 501.

https://doi.org/10.1182/blood.V128.22.501.501

Published: 2016

Journal Articles

Administration of Most Closely HLA-Matched Multivirus-Specific T Cells for the Treatment of EBV, CMV, AdV, HHV6, and BKV Post Allogeneic Hematopoietic Stem Cell Transplant

Bilal Omer, MD, Anastasia Papadopoulou, PhD, Nikita Koottiyaniyil, Adrian P. Gee, PhD, Swati Naik, MD, Caridad Marinez, MD, Leung Kathryn, MD, Ghadir S. Sasa, MD, Robert A. Krance, MD, Bambi Grilley, RPh, Malcolm K. Brenner, MD PhD, Cliona M. Rooney, PhD, Helen E. Heslop, MD, Ann M. Leen, PhD, Ifigeneia Tzannou, MD

Blood (2015) 126 (23): 622.

https://doi.org/10.1182/blood.V126.23.622.622

Published: 2015

Journal Articles

Adoptively-Transferred EBV-Specific T Cells to Prevent or Treat EBV-Related Lymphoproliferative Disease in Allogeneic HSCT Recipients - a Single Center Experience Spanning 22 Years

Ifigeneia Tzannou, MD, Bilal Omer, MD, Anastasia Papadopoulou, PhD, Ulrike Gerdemann, MD, Colton Smith, PhD, Adrian P. Gee, PhD, Bambi J Grilley, Malcolm K. Brenner, MB, PhD FRCP, FRCPath, Catherine M. Bollard, MD, Ann M. Leen, PhD, Cliona M. Rooney, PhD, Helen E. Heslop, MD

Blood (2015) 126 (23): 1926.

https://doi.org/10.1182/blood.V126.23.1926.1926

Published: 2015

Journal Articles

Optimizing the Manufacture of CAR-T Cells for Clinical Applications

Pradip Bajgain, Roopa Mucharla, Usanarat Anurathapan, Natalia Lapteva, Ann M. Leen, PhD, Helen E. Heslop, MD, Cliona M. Rooney, PhD, Juan F. Vera, MD

Blood (2012) 120 (21): 348.

https://doi.org/10.1182/blood.V120.21.348.348

Published: 2012

Journal Articles

Multicenter Study of “off-the-Shelf” Third Party Virus-Specific T Cells (VSTs) to Treat Adenovirus (Adv), Cytomegalovirus (CMV) or Epstein Barr Virus (EBV) Infection After Hemopoietic Stem Cell Transplantation (HSCT)

Ann M. Leen, PhD, Catherine M. Bollard, MD, Adam M. Mendizabal, MS, Elizabeth J. Shpall, MD, Paul Szabolcs, MD, Joseph H. Antin, MD, Neena Kapoor, MD, Sung-Yun Pai, MD, Scott D. Rowley, MD, Partow Kebriaei, M.D., Bambi J. Grilley, Adrian P. Gee, PhD, Malcolm K. Brenner, MD, PhD, Cliona M. Rooney, PhD, Helen E. Heslop, MD

Blood (2012) 120 (21): 457.

https://doi.org/10.1182/blood.V120.21.457.457

Published: 2012

Journal Articles

Safety and Clinical Efficacy of Rapidly-Generated Trivirus-Directed T Cells After Allogeneic Hematopoietic Stem Cell Transplant

Ulrike Gerdemann, MD, Usha L Katari, Jacqueline Keirnan, John A. Craddock, M.D., Janet Salinas, Hao Liu, PhD, Caridad Martinez, MD, Alana Kennedy-Nasser, MD, Kathryn Leung, MD, Stephen Gottschalk, MD, Adrian P. Gee, PhD, Robert A. Krance, MD, Malcolm K. Brenner, MD, PhD, Cliona M. Rooney, PhD, Helen E. Heslop, MD, Ann M. Leen, PhD

Blood (2012) 120 (21): 223.

https://doi.org/10.1182/blood.V120.21.223.223

Published: 2012

Journal Articles

Combining Oncolytic Vaccinia Virotherapy with Adoptive T Cell Therapy,

Minhtran Charlotte Ngo, Jun Ando, MD, PhD, Ann M. Leen, PhD, Caroline Breitbach, PhD, Anne Moon, David Kirn, MD, John Bell, PhD, Cliona M. Rooney, PhD

Blood (2011) 118 (21): 4042.

https://doi.org/10.1182/blood.V118.21.4042.4042

Published: 2011

Journal Articles

Towards Phase 2/3 Trials for Epstein - Barr Virus (EBV)-Associated Malignancies,

Jun Ando, MD, PhD, Minhtran Charlotte Ngo, Sravya Ennamuri, Jiali Sun, PhD, Helen E. Heslop, MD, Catherine M. Bollard, MD, Carl H. June, MD, Ann M. Leen, PhD, Stephen Gottschalk, MD, Cliona M. Rooney, PhD

Blood (2011) 118 (21): 4043.

https://doi.org/10.1182/blood.V118.21.4043.4043

Published: 2011

NARROW

Treatment of Severe, Drug-Refractory Viral Infections with Allogeneic, Off-the-Shelf Multi-Virus Specific T Cells in Patients Following HSCT: Results from a Phase 2 Study

Using Allogeneic, Off-the-Shelf, Sars-Cov-2-Specific T Cells to Treat High Risk Patients with COVID-19

T Cell Immunity Toward Viral- and Tumor-Antigens Is Preserved in MDS Patients

Targeting Lymphomas Using Non-Engineered, Multi-Antigen Specific T Cells

Myd88/CD40 Costimulation to Enhance the Antitumor Activity of CD123-ENG T-Cells for the Immunotherapy of AML

Adoptive T-Cell Therapy for Acute Lymphoblastic Leukemia Targeting Multiple Tumor Associated Antigens

Safety and Efficacy of Multiantigen-Targeted T Cells for Multiple Myeloma

Towards Functional Immune Monitoring in Allogeneic Hematopoietic Stem Cell Transpant Recipients

Adoptive Immunotherapy with Rapidly-Generated Multivirus-Specific T Cells Against AdV, EBV, CMV, HHV6 and BK after Allogeneic Hematopoietic Stem Cell Transplant

Evaluating Cyclin A1 As an Immunotherapeutic Target in Acute Myeloid Leukemia (AML)

Safety and Efficacy of Adoptively Transferred Donor-Derived Tumor-Directed T Cells with Relapsed AML Post-Allogeneic HSCT

Safety and Preliminary Efficacy of "Ready to Administer" Cytomegalovirus (CMV)-Specific T Cells for the Treatment of Patients with Refractory CMV Infection

Administration of Most Closely HLA-Matched Multivirus-Specific T Cells for the Treatment of EBV, CMV, AdV, HHV6, and BKV Post Allogeneic Hematopoietic Stem Cell Transplant

Administration of Most Closely HLA-Matched Multivirus-Specific T Cells for the Treatment of EBV, CMV, AdV, HHV6, and BKV Post Allogeneic Hematopoietic Stem Cell Transplant

Adoptively-Transferred EBV-Specific T Cells to Prevent or Treat EBV-Related Lymphoproliferative Disease in Allogeneic HSCT Recipients - a Single Center Experience Spanning 22 Years

Optimizing the Manufacture of CAR-T Cells for Clinical Applications

Multicenter Study of “off-the-Shelf” Third Party Virus-Specific T Cells (VSTs) to Treat Adenovirus (Adv), Cytomegalovirus (CMV) or Epstein Barr Virus (EBV) Infection After Hemopoietic Stem Cell Transplantation (HSCT)

Safety and Clinical Efficacy of Rapidly-Generated Trivirus-Directed T Cells After Allogeneic Hematopoietic Stem Cell Transplant

Combining Oncolytic Vaccinia Virotherapy with Adoptive T Cell Therapy,

Towards Phase 2/3 Trials for Epstein - Barr Virus (EBV)-Associated Malignancies,

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American Society of Hematology

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ASH Publications

American Society of Hematology

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