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Andrzej Bartke, Ph.D.
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Journal Articles

A Novel Perspective on Stem Cells, Tissue Senescence and Aging: Pluripotent Very Small Embryonic-Like Stem Cells (VSELs) and Hematopoietic Stem Cells (HSCs) Are Prematurely Depleted in Adult Bone Marrow (BM) in Response to Prolonged Growth Hormone/Insulin-Like Growth Factor-1 Signaling (IIS) and Chronic Increase in Caloric Uptake

Magda Kucia, Ph.D., Janina Ratajczak, MD, PhD, Dong-Myung Shin, PhD, Rui Liu, Ph.D., Michal Masternak, Ph.D., Andrzej Bartke, Ph.D., Mariusz Z Ratajczak, M.D., Ph.D.
Journal: Blood
Blood (2011) 118 (21): 4818.
https://doi.org/10.1182/blood.V118.21.4818.4818
Published: 2011
Journal Articles

Long-Term In Vivo Studies in Mice Unexpectedly Reveal That Prolonged Growth Hormone (GH) and Insulin/Insulin-Like Growth Factor-1 (IGF-1) Signaling Have a Negative Effect on Normal Bone Marrow Hematopoiesis – Implications for GH-Based “rejuvenation” Therapies,

Janina Ratajczak, MD, PhD, Rui Liu, Ph.D., Magda Kucia, Ph.D., Andrzej Bartke, Ph.D., Mariusz Z Ratajczak, MD, PhD, DSc
Journal: Blood
Blood (2011) 118 (21): 3422.
https://doi.org/10.1182/blood.V118.21.3422.3422
Published: 2011
Journal Articles

Unexpected Evidence That Chronic IGF-1 Deficiency In Laron Dwarf Mice Maintains High Levels of Hematopoietic Stem Cells (HSCs) In BM - Are HSCs Gradually Depleted From BM with Age In An IGF-1–dependent Manner? Implications for the Novel Effect of Caloric Restriction on the Hematopoietic Stem Cell Compartment and Longevity.

Janina Ratajczak, MD, PhD, Wu Wan, MS, Rui Liu, MB, BS, Dong-Myung Shin, Ph.D., Magdalena Kucia, PhD, Andrzej Bartke, Ph.D., Mariusz Z Ratajczak, MD, PhD, DSc
Journal: Blood
Blood (2010) 116 (21): 1551.
https://doi.org/10.1182/blood.V116.21.1551.1551
Published: 2010
Journal Articles

The Number of Very Small Embryonic Like Stem Cells (VSELs) Decreases During Aging In An IGF-1-Dependent Manner - a Novel Link Between Aging, Caloric Restriction, and the Size of the Stem Cell Pool

Dong-Myung Shin, Ph.D., Wu Wan, BS, Rui Liu, MB, BS, Janina Ratajczak, MD, PhD, Andrzej Bartke, Ph.D., Magdalena Kucia, PhD, Mariusz Z Ratajczak, MD, PhD, DSc
Journal: Blood
Blood (2010) 116 (21): 4796.
https://doi.org/10.1182/blood.V116.21.4796.4796
Published: 2010