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Andrew J. Gale, PhD
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Journal Articles

Distinct Mechanism of Anti-Hemophilic FVIII Activation By Nascent FXa in the Tissue Factor-FVIIa Coagulation Initiation Complex Resistant to FXa-Directed Inhibition

Yuichi Kamikubo, PhD, Grazia Loredana Mendolicchio, MD PhD, Antonella Zampolli, PhD, Patrizia Marchese, PhD, Andrew J. Gale, PhD, Sriram Krishnaswamy, PhD, Andras Gruber, MD, Lars Christian Petersen, Wolfram Ruf, MD, Zaverio M Ruggeri, MD
Journal: Blood
Blood (2014) 124 (21): 2803.
https://doi.org/10.1182/blood.V124.21.2803.2803
Published: 2014
Journal Articles

Synergistic Effect in Bleed Reduction By super fva and Recombinant Human FVIIa in Vivo Suggests a Novel Bypassing Strategy for Hemophilia Patients with Inhibitors

Vikas Bhat, PhD, Annette von Drygalski, MD PharmD, Andrew J. Gale, PhD, John H. Griffin, PhD, Laurent O. Mosnier, PhD
Journal: Blood
Blood (2014) 124 (21): 692.
https://doi.org/10.1182/blood.V124.21.692.692
Published: 2014
Journal Articles

Reversal of Novel Oral Anticoagulant (NOAC)-Induced Bleeding in Mice By Engineered super factor Va

Vikas Bhat, PhD, Andrew J. Gale, PhD, John H. Griffin, PhD, Laurent O. Mosnier, PhD, Annette von Drygalski, MD PharmD
Journal: Blood
Blood (2014) 124 (21): 695.
https://doi.org/10.1182/blood.V124.21.695.695
Published: 2014
Journal Articles

Activation-Resistant Homozygous Protein C R229W Mutation Causing Familial Perinatal Intracranial Hemorrhage

Abdulrahman Alsultan, MD, Andrew J. Gale, PhD, Kadijah Kurban, MD, Mohammed Khalifah, MD, Fahad B. Albadr, MD, John H. Griffin, PhD
Journal: Blood
Blood (2013) 122 (21): 3587.
https://doi.org/10.1182/blood.V122.21.3587.3587
Published: 2013
Journal Articles

An Engineered Factor Fva Prevents Bleeding Induced By Anticoagulant Wild Type Activated Protein C

Annette Von Drygalski, MD, PharmD, Andrew J. Gale, PhD, Laurent Burnier, PhD, Thomas J. Cramer, PhD, John H. Griffin, PhD, Laurent O. Mosnier, PhD
Journal: Blood
Blood (2013) 122 (21): 203.
https://doi.org/10.1182/blood.V122.21.203.203
Published: 2013
Journal Articles

Superior in Vivo Hemostatic Properties of an Engineered Factor Va Variant for Hemophilia Mice

Annette Von Drygalski, MD, PharmD, Thomas J. Cramer, PhD, John H. Griffin, PhD, Andrew J. Gale, PhD, Laurent O. Mosnier, PhD
Journal: Blood
Blood (2012) 120 (21): 17.
https://doi.org/10.1182/blood.V120.21.17.17
Published: 2012
Journal Articles

Factor V as Anticoagulant Cofactor for Activated Protein C in Factor Va Inactivation

Thomas J Cramer, MSc., John H. Griffin, PhD, Andrew J. Gale, PhD
Journal: Blood
Blood (2008) 112 (11): 3075.
https://doi.org/10.1182/blood.V112.11.3075.3075
Published: 2008
Journal Articles

The Neutrophil Proteases, Elastase and Cathepsin G, May Modulate the Activity of Factor VIII.

Andrew J. Gale, PhD, Diana Rozenshteyn, Justin Riceberg
Journal: Blood
Blood (2006) 108 (11): 1716.
https://doi.org/10.1182/blood.V108.11.1716.1716
Published: 2006
Journal Articles

Factor Xa Binding Sites on Factor Va in the Prothrombinase Complex.

Andrew J. Gale, PhD, John H. Griffin, PhD
Journal: Blood
Blood (2004) 104 (11): 1713.
https://doi.org/10.1182/blood.V104.11.1713.1713
Published: 2004