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Amin Sobh, PhD
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Journal Articles

Adenylate Kinase 2 Is a Selective Dependency in NSD2-High Multiple Myeloma

Amin Sobh, PhD, Charlotte Kaestner, Jianping Li, MD, Alberto Riva, PhD, Richard Lynn Bennett, PhD, Jonathan D. Licht, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 31.
https://doi.org/10.1182/blood-2020-141266
Published: 2020
Journal Articles

Nelfinavir Overcomes Proteasome Inhibitor Resistance in Multiple Myeloma By Modulating Membrane Lipid Bilayer Composition and Fluidity

Andrej Besse, Lenka Besse, Sara C. Stolze, Amin Sobh, PhD, Esther A. Zaal, Alwin J van der Ham, Mario Ruiz, Santosh Phuyal, Lorina Büchler, Marc Sathianathan, Bogdan I. Florea, Jan Borén, Marcus Ståhlman, Alex Loguinov, Bart Everts, Celia R. Berkers, Marc Pilon, Hesso Farhan, Chris D. Vulpe, Herman S. Overkleeft, Christoph Driessen, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 11.
https://doi.org/10.1182/blood-2020-136253
Published: 2020
Journal Articles

Identification of Genetic Vulnerabilities and Synthetic-Lethal Targets in NSD2-High Multiple Myeloma

Amin Sobh, PhD, Charlotte Kaestner, Alberto Riva, PhD, Jonathan D. Licht, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3757.
https://doi.org/10.1182/blood-2019-125951
Published: 2019
Journal Articles

Genome-Scale CRISPR-Cas9 Synthetic Lethal Screening of AML Cell Line Identified Functional Modulators of Etoposide Resistance Predictive of Clinical Outcome in AML Patients

Roya Rafiee, M.Sc., PhD, Amin Sobh, PhD, Abdelrahman H. Elsayed, MSc, Abderrahmane Tagmount, PhD, Chris D Vulpe, MD PhD, Jatinder K Lamba, M.Sc., PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2685.
https://doi.org/10.1182/blood-2019-131312
Published: 2019
Journal Articles

CRISPR Dropout Screens Identify DHODH, PIK3C3 , and Crkl as Potential Therapeutic Targets in Acute Myeloid Leukemia

Gregory Takacs, BS, Yujia Zhou, BS,BA, David J. King, BS, Amy Meacham, MS, Loguinov Alex, PhD, Abderrahmane Tagmount, PhD, Amin Sobh, PhD, Max Russo, BS, Chris D Vulpe, MD PhD, Christopher R. Cogle, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1452.
https://doi.org/10.1182/blood-2019-128180
Published: 2019