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Alan H. Lazarus, PhD.
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Journal Articles

Anti-Glycoprotein V Autoantibodies in Patients with Immune Thrombocytopenia: Regularly Detectable and Functionally Relevant

Richard Vollenberg, MD, Rabie Jouni, Peter A. A. Norris, BSc, Monika Burg-Roderfeld, PhD, Nina Cooper, MD, Mathias J Rummel, MD PhD, Gregor Bein, MD PhD, Irene Marini, Alan H Lazarus, PhD, Tamam Bakchoul, MD PhD, Ulrich J Sachs, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1141.
https://doi.org/10.1182/blood-2018-99-118090
Published: 2018
Journal Articles

Fcγ Receptors I and III on Splenic Macrophages Mediate GPIIb/IIIa Autoantibody-Dependent Phagocytosis of Platelets in Human Immune Thrombocytopenia

Peter A. A. Norris, BSc, George B. Segel, MD, Ulrich J Sachs, MD PhD, Behnaz Bayat, PhD, Gestur Vidarsson, PhD, Rick Kapur, MDPhDMSc, Christine M. Cserti-Gazdewich, BSc, MD FRCPC, Jeannie Callum, MD, Yulia Lin, MD FRCPC, Richard Burack, MD PhD, John W Semple, PhD, Alan H Lazarus, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 129.
https://doi.org/10.1182/blood-2018-99-117650
Published: 2018
Journal Articles

Antibodies Against Macrophage CD44 Protect Platelets from FcγR-Mediated Phagocytosis: A Potential Mechanism for CD44 Antibody Amelioration of Murine Immune Thrombocytopenia

Peter A A Norris, BSc, Yawen Wang, MD, Guangheng Zhu, MD, Lin Wang, MD, Ming Huo, MD, Gregory D Fairn, PhD, Heyu Ni, MD MSc, PhD, Alan H Lazarus, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3639.
https://doi.org/10.1182/blood.V130.Suppl_1.3639.3639
Published: 2017
Journal Articles

Erythrocyte-Specific Antibodies As a Potential New Therapeutic Modality in Autoimmune and Inflammatory Disorders Beyond Immune Thrombocytopenia (ITP)

Andrew R Crow, BRT, Rick Kapur, MDPhDMSc, Mark Jen, MSc, Patrick J Mott, MSc, Danielle Marjoram, MSc, Alaa Amash, PhD, Simrat S Kahlon, BSc, Issaka Yougbare, PhD, Heyu Ni, MD MSc, PhD, Michael Kim, BSc, John W Semple, PhD, Alan H Lazarus, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 231.
https://doi.org/10.1182/blood.V130.Suppl_1.231.231
Published: 2017
Journal Articles

Amelioration of Immune Thrombocytopenia in Human CD44 Transgenic Mice By Anti-Human CD44 Antibodies

Andrew R. Crow, BSc, Alaa Amash, PhD, Alan H Lazarus, PhD
Journal: Blood
Blood (2016) 128 (22): 167.
https://doi.org/10.1182/blood.V128.22.167.167
Published: 2016
Journal Articles

Anti-RhD Mediates Loss of RhD Antigen Following Anti-RhD Infusion

Harold Clifford Sullivan, MD, Connie Maridith Arthur, PhD, Seema Patel, PhD, Jeanne E. Hendrickson, MD, Alan H Lazarus, PhD, Sean R. Stowell, MD PhD
Journal: Blood
Blood (2015) 126 (23): 3570.
https://doi.org/10.1182/blood.V126.23.3570.3570
Published: 2015
Journal Articles

Unveiling the Regulatory Role of CD8+ T-Cells in the Pathogenesis and Effective Steroid Treatment in ITP

Li Ma, PhD, Elisa K. Simpson, MSc., June Li, MSc, Min Xuan, PhD, Miao Xu, MSc, MD, Laura Baker, BSc., Yan Shi, MD, Guangheng Zhu, MD, Pingguo Chen, MD PhD, Alan H Lazarus, PhD, John J. Freedman, MD, Heyu Ni, MD PhD
Journal: Blood
Blood (2014) 124 (21): 576.
https://doi.org/10.1182/blood.V124.21.576.576
Published: 2014
Journal Articles

Megakaryocyte Abnormalities Occur In The Absence Of Cell-Mediated Immunity In a Murine Model Of Passive Immune Thrombocytopenia (ITP)

John W. Semple, PhD, Kristin Hunt, Yu Hou, Rukhsana Aslam, PhD, Edwin R. Speck, Heyu Ni, MD, PhD, Alan H Lazarus, PhD
Journal: Blood
Blood (2013) 122 (21): 3537.
https://doi.org/10.1182/blood.V122.21.3537.3537
Published: 2013
Journal Articles

Ivig, but Not a Monoclonal Anti-RBC Antibody, Requires the Presence of Gr-1 + Cells to Ameliorate Immune Thrombocytopenia in a Murine Model

Andrew R. Crow, BSc, Alan H Lazarus, PhD
Journal: Blood
Blood (2012) 120 (21): 268.
https://doi.org/10.1182/blood.V120.21.268.268
Published: 2012
Journal Articles

CD44 Antibody Mediated Amelioration of Murine ITP: Evidence for a Similar Strain Dependent FcγRIIB Requirement As Compared to Ivig

Andrew R. Crow, BSc, Alan H Lazarus, PhD
Journal: Blood
Blood (2012) 120 (21): 1084.
https://doi.org/10.1182/blood.V120.21.1084.1084
Published: 2012
Journal Articles

Intravenous Gammaglobulin (IVIg) Therapy Prevents Antibody-Mediated Transfusion Related Acute Lung Injury (TRALI) by Directly Inhibiting Recipient Neutrophil Activation in a Murine Model

John W. Semple, PhD, Michael Kim, BSc, Jing Hou, Young Jin Lee, Arata Tabuchi, Wolfgang M. Kuebler, MD, PhD, Alan H Lazarus, PhD
Journal: Blood
Blood (2011) 118 (21): 42.
https://doi.org/10.1182/blood.V118.21.42.42
Published: 2011
Journal Articles

Amelioration of Murine Immune Thrombocytopenia by CD44 Antibodies: a Potential Therapy for ITP?

Andrew R. Crow, Seng Song, Sara J Suppa, Alan H Lazarus, PhD
Journal: Blood
Blood (2010) 116 (21): 2528.
https://doi.org/10.1182/blood.V116.21.2528.2528
Published: 2010
Journal Articles

Expression of the Neonatal Fc Receptor FcRn Is Not Required for the Amelioration of Murine ITP by IVIg or a Monoclonal Antibody

Andrew R. Crow, Sara J Suppa, Alan H Lazarus, PhD
Journal: Blood
Blood (2010) 116 (21): 2529.
https://doi.org/10.1182/blood.V116.21.2529.2529
Published: 2010
Journal Articles

IVIg-Primed Splenocytes Ameliorate Murine ITP in an MHC Class II-Unrestricted Manner.

Andrew R. Crow, BRT, Vinayakumar Siragam, PhD, John Freedman, MD, Alan H. Lazarus, PhD
Journal: Blood
Blood (2007) 110 (11): 102.
https://doi.org/10.1182/blood.V110.11.102.102
Published: 2007
Journal Articles

IVIg-Primed Leukocytes Offer Longer Protection in the Amelioration of ITP Than IVIg.

Andrew R. Crow, BSc, Davor Brinc, BSc, Vinayakumar Siragam, PhD, John Freedman, MD, Alan H. Lazarus, PhD
Journal: Blood
Blood (2006) 108 (11): 703.
https://doi.org/10.1182/blood.V108.11.703.703
Published: 2006
Journal Articles

Inhibition of Immune Thrombocytopenic Purpura (ITP) by an Orally Bioavailable Inhibitor of Syk Kinase Activity.

Andrew R. Crow, BSc, Vinayakumar Siragam, PhD, John Freedman, MD, Elliott B. Grossbard, MD, Esteban S. Masuda, PhD, Polly Pine, PhD, Alan H. Lazarus, PhD
Journal: Blood
Blood (2005) 106 (11): 2165.
https://doi.org/10.1182/blood.V106.11.2165.2165
Published: 2005
Journal Articles

A Role for IL-1Receptor Antagonist in the Acute Therapeutic Effects of IVIg?.

Andrew R. Crow, BSc, Seng Song, MD, John Freedman, MD, John W. Semple, PhD, Alan H. Lazarus, PhD
Journal: Blood
Blood (2004) 104 (11): 2064.
https://doi.org/10.1182/blood.V104.11.2064.2064
Published: 2004
Journal Articles

Can IVIg Preparations with Specificity for Soluble Antigens Mimic the Therapeutic Effects of IVIg in the Treatment of Immune Thrombocytopenia?.

Vinayakumar Siragam, PhD, Davor Brinc, BSc, Andrew R. Crow, BSc, Seng Song, MD, John Freedman, MD, Alan H. Lazarus, PhD.
Journal: Blood
Blood (2004) 104 (11): 2073.
https://doi.org/10.1182/blood.V104.11.2073.2073
Published: 2004