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Alan D. D’Andrea, MD
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Journal Articles

STAG2 Mutations Alter Cohesin Ring Function and Provide Therapeutic Vulnerabilities in Acute Myeloid Leukemia

Zuzana Tothova, MD PhD, John M. Krill-Burger, MS, Daniel S. Day, PhD, J. Erika Haydu, MD PhD, Brian J. Abraham, PhD, Catherine C. Landers, BA, Edyta Malolepsza, PhD, Christina R. Hartigan, BS, Amie Holmes, PhD, Melanie Donahue, BS, Katerina D. Popova, BA, Sebastian Koochaki, MS, Jeanne Rivera, BSc, Michael Seiler, PhD, Denes Hnisz, PhD, Edwin Chen, PhD, Silvia Buonamici, PhD, Monica Schenone, PhD, Alan D. D'Andrea, MD, Steven A. Carr, PhD, Richard A. Young, PhD, Benjamin L. Ebert, MDPhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 940.
https://doi.org/10.1182/blood-2018-99-117480
Published: 2018
Journal Articles

The Fanconi Pathway in Pediatric T-Cell Acute Lymphoblastic Leukemia

Gayle P. Pouliot, MD PhD, Melissa A. Burns, MD, James Degar, Chau Vo, Lisa Moreau, Justine E. Roderick, PhD, Bose Kochupurakkal, PhD, Sofie Peirs, PhD, Bjorn Menten, PhD, Mignon L. Loh, MD, Stephen P. Hunger, MD, Lewis B. Silverman, MD, Stephen E. Sallan, MD, Marian H. Harris, MD PhD, Kristen E. Stevenson, MS, Donna S. Neuberg, ScD, David M. Weinstock, MD, Andrew P. Weng, MD PhD, Michelle Kelliher, PhD, Pieter Van Vlierberghe, PhD, Alan D. D'Andrea, MD, Alejandro Gutierrez, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2722.
https://doi.org/10.1182/blood.V130.Suppl_1.2722.2722
Published: 2017
Journal Articles

Hyperactive Non-Canonical TGF-β Pathway Signaling in Fanconi Anemia Bone Marrow Stromal Cells Contributes to Growth Suppression

Kevin O'Connor, Sofia Vidal-Cardenas, PhD, Haojian Zhang, PhD, Alfredo Rodriguez, Lisa Moreau, Chunyu Yang, Michael W Epperly, PhD, Markus Grompe, MD, Akiko Shimamura, MD PhD, Joel S. Greenberger, MD, Kalindi Parmar, PhD, Alan D D'Andrea, MD
Journal: Blood
Blood (2016) 128 (22): 1039.
https://doi.org/10.1182/blood.V128.22.1039.1039
Published: 2016
Journal Articles

TGF-β Pathway Inhibition Rescues the Function of Hematopoietic Stem and Progenitor Cells Derived from Patients with Fanconi Anemia

Haojian Zhang, PhD, David Kozono, MD PhD, Kevin O'Connor, Alix Rousseau, Lisa Moreau, Emily Gaudiano, BS, Joel S Greenberger, MD, Grover C. Bagby, Jr., MD MACP, Jean Soulier, MD PhD, Markus Grompe, MD, Kalindi Parmar, PhD, Alan D D'Andrea, MD
Journal: Blood
Blood (2015) 126 (23): 297.
https://doi.org/10.1182/blood.V126.23.297.297
Published: 2015
Journal Articles

Bone Marrow Failure in Fanconi Anemia from Hyperactive TGF-β Signaling

Haojian Zhang, PhD, David Kozono, MD PhD, Kevin O'Connor, BA, Sofia Vidal-Cardenas, PhD, Abigail Hamilton, BA, Emily Gaudiano, BS, Joel S. Greenberger, MD, Markus Grompe, MD, Kalindi Parmar, PhD, Alan D. D'Andrea, MD
Journal: Blood
Blood (2014) 124 (21): 356.
https://doi.org/10.1182/blood.V124.21.356.356
Published: 2014
Journal Articles

Small Molecule Inhibitors of USP1 Target ID1 Degradation in Leukemic Cells and Cause Cytotoxicity

Helena Mistry, Ph.D., Grace Hsieh, M.D., Sara Buhrlage, Ph.D, Min Huang, Ph.D., Eunmi Park, Ph.D., Gregory Cuny, Ph.D., Ilene Galinsky, ANP, Richard M. Stone, MD, Nathanael S Gray, PhD, Kalindi Parmar, PhD, Alan D. D'Andrea, MD
Journal: Blood
Blood (2013) 122 (21): 2906.
https://doi.org/10.1182/blood.V122.21.2906.2906
Published: 2013
Journal Articles

Characterization Of Full-Length, Recombinant Amsh, USP9x, and USP1: Clinically-Relevant Deubiquitinases Involved In Hematological Malignancies

Nate Russell, Trevor Taylor, Kalindi Parmar, PhD, Alan D. D'Andrea, MD, Bradley B Brasher, Ph.D., Francesco D Melandri
Journal: Blood
Blood (2013) 122 (21): 4224.
https://doi.org/10.1182/blood.V122.21.4224.4224
Published: 2013
Journal Articles

Fanconi Anemia: Emerging Therapeutic Opportunities

Markus Grompe, MD, John Postlethwait, Professor, Alan D. D'Andrea, MD, Susan B. Olson, Qingshuo Zhang, Grover C. Bagby, Jr.
Journal: Blood
Blood (2012) 120 (21): SCI-1.
https://doi.org/10.1182/blood.V120.21.SCI-1.SCI-1
Published: 2012
Journal Articles

Gene-Correction Rescues Reprogramming of Fanconi Anemia Fibroblasts and Enables Hematopoietic Differentiation of FA Induced Pluripotent Stem Cells in Vitro and In Vivo

Lars Mueller, MD, Michael D. Milsom, PhD, Chad Harris, Rutesh Vyas, Kristina Brumme, Kalindi Parmar, PhD, Axel Schambach, MD PhD, Elke Grassman, Ph.D., In-Hyun Park, PhD, London Wendy, PhD, Kelly Strait, Thorsten Schlaeger, Ph.D, Alexander L. Devine, Alan D. D'Andrea, MD, George Q. Daley, MD, PhD, David A. Williams, MD
Journal: Blood
Blood (2011) 118 (21): 672.
https://doi.org/10.1182/blood.V118.21.672.672
Published: 2011
Journal Articles

Cytokinesis Failure In Fanconi Anemia Pathway Deficient Hematopoietic Cells

Kalindi Parmar, Ph.D, Patrizia Vinciguerra, Ph.D., Susana Godinho, Ph.D., Abigail Hamilton, BA, David Pellman, MD, Alan D. D'Andrea, MD
Journal: Blood
Blood (2010) 116 (21): 878.
https://doi.org/10.1182/blood.V116.21.878.878
Published: 2010
Journal Articles

Mechanisms of Resistance to Reprogramming of Cells Defective In the Fanconi Anemia DNA Repair Pathway

Lars Mueller, MD, Michael D. Milsom, PhD, Kristina Brumme, Chad Harris, Kalindi Parmar, PhD, Kaya Zhu, London Wendy, PhD, Kelly Strait, Alan D. D'Andrea, MD, George Q. Daley, MD, PhD, David A. Williams, MD
Journal: Blood
Blood (2010) 116 (21): 196.
https://doi.org/10.1182/blood.V116.21.196.196
Published: 2010
Journal Articles

Hematopoietic Stem Cell Defects in Novel Fanconi Anemia Mouse Models

Kalindi Parmar, PhD, Jung Min Kim, PhD, Akiko Shimamura, MD, PhD, Anna Stuckert, Mary K DeLoach, Kaya Zhu, Peter M. Mauch, MD, Jeffery Kutok, MD, PhD, Jon Aster, MD, PhD, Koichi Akashi, MD, PhD, D. Gary Gilliland, MD, PhD, Alan D. D’Andrea, MD
Journal: Blood
Blood (2008) 112 (11): 440.
https://doi.org/10.1182/blood.V112.11.440.440
Published: 2008
Journal Articles

Functional Interaction between FANCD2 and ATM in the DNA Damage Response.

Steven P. Margossian, MD, PhD, Gary Ho, Richard Kennedy, MD, PhD, Alan D. D’Andrea, MD
Journal: Blood
Blood (2005) 106 (11): 181.
https://doi.org/10.1182/blood.V106.11.181.181
Published: 2005