1-11 of 11
Adam Siddiqui-Jain
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

The Oral CDK9 Inhibitor, TP-1287, Is Active in Non-Clinical Models of Multiple Myeloma

Ethika Tyagi, PhD, Clifford Whatcott, PhD, Jason M Foulks, PhD, Adam Siddiqui-Jain, PhD, David J. Bearss, PhD, Steven L. Warner, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3269.
https://doi.org/10.1182/blood-2018-99-120047
Published: 2018
Journal Articles

The CDK9 Inhibitor, Alvocidib, Potentiates the Non-Clinical Activity of Azacytidine or Decitabine in an MCL-1-Dependent Fashion, Supporting Clinical Exploration of a Decitabine and Alvocidib Combination

Wontak Kim, Clifford Whatcott, PhD, Adam Siddiqui-Jain, PhD, Stephen Anthony, DO, David J. Bearss, PhD, Steven L. Warner, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4355.
https://doi.org/10.1182/blood-2018-99-119793
Published: 2018
Journal Articles

TP-0184 Inhibits ALK2/ACVR1, Decreases Hepcidin Levels, and Demonstrates Activity in Preclinical Mouse Models of Functional Iron Deficiency

Peter Peterson, PhD, W K, Clifford Whatcott, PhD, Adam Siddiqui-Jain, PhD, Steven Weitman, MD PhD, Mark Kieran, MD PhD, David J. Bearss, PhD, Steven L. Warner, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 937.
https://doi.org/10.1182/blood.V130.Suppl_1.937.937
Published: 2017
Journal Articles

Alvocidib Potentiates the Activity of Venetoclax in Preclinical Models of Acute Myeloid Leukemia

Clifford J. Whatcott, PhD, James M Bogenberger, PhD, Wontak Kim, Hillary Haws, Nanna Hansen, M.S., Devora Delman, B.S., Lisa Sproat, MD MSW, Jeanne Palmer, MD, Ruben A. Mesa, MD, Peter Peterson, PhD, Adam Siddiqui-Jain, PhD, Steven Weitman, MD PhD, David J. Bearss, PhD, Steven L. Warner, PhD, Raoul Tibes, MD PhD
Journal: Blood
Blood (2016) 128 (22): 1652.
https://doi.org/10.1182/blood.V128.22.1652.1652
Published: 2016
Journal Articles

The ALK-2 Inhibitor, TP-0184, Demonstrates High Distribution to the Liver Contributing to Significant Preclinical Efficacy in Mouse Models of Anemia of Chronic Disease

Peter Peterson, PhD, Wontak Kim, Hillary Haws, Clifford J. Whatcott, PhD, Adam Siddiqui-Jain, PhD, David J. Bearss, PhD, Steven L. Warner, PhD
Journal: Blood
Blood (2016) 128 (22): 263.
https://doi.org/10.1182/blood.V128.22.263.263
Published: 2016
Journal Articles

ALK2 Inhibition Via TP-0184 Abrogates Inflammation-Induced Hepcidin Expression and Is a Potential Therapeutic for Anemia of Chronic Disease

Peter Peterson, PhD, Katherine K. Soh, Ye Sol Lee, Wontak Kim, Clifford J. Whatcott, PhD, Adam Siddiqui-Jain, PhD, David J. Bearss, PhD, Steven L. Warner, PhD
Journal: Blood
Blood (2015) 126 (23): 273.
https://doi.org/10.1182/blood.V126.23.273.273
Published: 2015
Journal Articles

Alvocidib Potentiates the Activity of Azacytidine in an MCL-1-Dependent Fashion

Wontak Kim, Katherine K. Soh, Jeremiah J. Bearss, Ye Sol Lee, Peter Peterson, PhD, Clifford J. Whatcott, PhD, Adam Siddiqui-Jain, PhD, Steven Weitman, MDPhD, James M Bogenberger, PhD, Raoul Tibes, MD PhD, David J. Bearss, PhD, Steven L. Warner, PhD
Journal: Blood
Blood (2015) 126 (23): 1343.
https://doi.org/10.1182/blood.V126.23.1343.1343
Published: 2015
Journal Articles

Inhibition of Axl Kinase Reverses the Mesenchymal Phenotype in Leukemic Cells through the Disruption of Retinoic Acid Signaling

Katherine K. Soh, Brigham L. Bahr, Jeremiah J. Bearss, Wontak Kim, Peter Peterson, PhD, Clifford J. Whatcott, PhD, Adam Siddiqui-Jain, PhD, David J. Bearss, PhD, Steven L. Warner, PhD
Journal: Blood
Blood (2015) 126 (23): 3253.
https://doi.org/10.1182/blood.V126.23.3253.3253
Published: 2015
Journal Articles

Alvocidib Potentiates the Activity of Cytarabine and Mitoxantrone through the Targeting of MCL-1 When Administered in a Time Sequential Regimen in AML

Wontak Kim, Brigham L. Bahr, Katherine K. Soh, Jeremiah J. Bearss, Ye Sol Lee, Peter Peterson, PhD, Clifford J. Whatcott, PhD, Adam Siddiqui-Jain, PhD, Steven Weitman, MDPhD, David J. Bearss, PhD, Steven L. Warner, PhD
Journal: Blood
Blood (2015) 126 (23): 3799.
https://doi.org/10.1182/blood.V126.23.3799.3799
Published: 2015
Journal Articles

CX-4945, a Selective and Orally Bioavailable Inhibitor of Protein Kinase CK2 Inhibits PI3K/Akt, JAK-STAT and NF-κB Signaling and Induces Apoptosis In Multiple Myeloma Cells

Caroline Ho, MS, Rachel Rice, BS, Denis Drygin, PhD, Josh Bliesath, BS, Nicole Streiner, BS, Adam Siddiqui-Jain, PhD, Chris Proffitt, BS, Sean O'Brien, PhD, Kenna Anderes, PhD
Journal: Blood
Blood (2010) 116 (21): 787.
https://doi.org/10.1182/blood.V116.21.787.787
Published: 2010
Journal Articles

Discovery of Selective Small Molecule Pan-Pim Kinase Inhibitors with Potent Oral Efficacy in Murine Xenograft Models.

Sean O'Brien, PhD, Mustapha Haddach, PhD, Cosmin Borsan, Jerome Michaux, Pauline Kerdoncuff, Mike Schwaebe, Fabrice Pierre, PhD, Eric Stefan, PhD, Anne Sophie Nedellec, Adam Siddiqui-Jain, PhD, Nicole Streiner, BS, Diwata Macalino, BS, Denis Drygin, Phd, Caroline Ho, MS, Josh Bliesath, BS, May Omori, Ryan Stansfield, BS, Jennifer Phung, David Ryckman, PhD, William Rice, PhD, Kenna Anderes, PhD
Journal: Blood
Blood (2009) 114 (22): 1726.
https://doi.org/10.1182/blood.V114.22.1726.1726
Published: 2009