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Journal Articles

Regulated Natural Killer Cell Expansion and Anti-Tumor Activity with Inducible MyD88/CD40

Xiaomei Wang, PhD, Wei-Chun Chang, PhD, Daniel L. Jasinski, PhD, Jan L. Medina, BS, Ming Zhang, BS, Aaron Foster, PhD, David M. Spencer, PhD, J. Henri Bayle, PhD

Blood (2018) 132 (Supplement 1): 4550.

https://doi.org/10.1182/blood-2018-99-120151

Published: 2018

Journal Articles

A Simplified Method for Transduction and Expansion of T Cells for Clinical Application

Mariam Khalil, Aaron Foster, PhD, Christine Gagliardi, PhD

Blood (2018) 132 (Supplement 1): 4555.

https://doi.org/10.1182/blood-2018-99-119254

Published: 2018

Journal Articles

T- and B-Cell Neogenesis Recovers Efficiently in Children with Acute Leukemia Given an Alpha-Beta T-Cell Depleted Haplo-HSCT Followed By Infusion of Donor T-Cells Genetically Modified with Inducible Caspase 9 Suicide Gene (BPX-501 cells)

Marialuigia Catanoso, MD, Emmanuel Clave, PhD, Corinne Douay, Mattia Algeri, MD, Isabelle Fournier, Valentina Bertaina, Itaua Leston Araujo, MSc, Francesca Del Bufalo, MD, Federica Galaverna, MD, Cecilia Surace, PhD, Alice Bertaina, MD PhD, Pietro Merli, MD, Aaron Foster, PhD, Antoine Toubert, MD PhD, Franco Locatelli

Blood (2018) 132 (Supplement 1): 4560.

https://doi.org/10.1182/blood-2018-99-116536

Published: 2018

Journal Articles

Characterization of Allogeneic T Cells Expressing Inducible Caspase-9 Following Adoptive Transfer in Children Receiving an HLA-Haploidentical Hematopoietic Stem Cell Transplant for the Treatment of Myeloid Malignancies

Joanne Shaw, PhD, Xiaoou Zhou, MD PhD, An Lu, Valentina Bertaina, Daria Pagliara, MD PhD, Melissa Aldinger, PharmD, David M. Spencer, PhD, Franco Locatelli, Aaron Foster, PhD

Blood (2018) 132 (Supplement 1): 4534.

https://doi.org/10.1182/blood-2018-99-119779

Published: 2018

Journal Articles

Differential Expression of Inducible Caspase-9 (iC9) in Allogeneic T Cells Allows Selective Depletion of Activated T Cells Following Exposure to Rimiducid and Permits In Vivo Allodepletion

Xiaoou Zhou, MD PhD, An Lu, Kelly L Sharp, Margie Harris, Madhavi Anumula, MS, J. Bayle, PhD, David M. Spencer, PhD, Aaron Foster, PhD, Joanne Shaw, PhD

Blood (2018) 132 (Supplement 1): 3496.

https://doi.org/10.1182/blood-2018-99-119285

Published: 2018

Journal Articles

Inducible MyD88/CD40 Enhances Proliferation and Survival of PRAME-Specific TCR-Engineered T Cells and Increases Anti-Tumor Effects in Myeloma

Tsvetalina Hoang, PhD, Aaron Foster, PhD, Jeannette Crisostomo, An Lu, Annemarie Moseley, MDPhD, Mirjam H.M. Heemskerk, PhD, Kevin M Slawin, MD, David M Spencer, PhD

Blood (2015) 126 (23): 1886.

https://doi.org/10.1182/blood.V126.23.1886.1886

Published: 2015

Journal Articles

Inducible MyD88/CD40 Allows Rimiducid-Dependent Activation to Control Proliferation and Survival of Chimeric Antigen Receptor-Modified T Cells

Aaron Foster, PhD, Aruna Mahendravada, Nicholas P Shinners, PhD, Peter Chang, PhD, An Lu, Eva Morschl, PhD, Joanne Shaw, PhD, Sunandan Saha, PhD, Kevin M Slawin, MD, David M Spencer, PhD

Blood (2015) 126 (23): 4295.

https://doi.org/10.1182/blood.V126.23.4295.4295

Published: 2015

Journal Articles

Expression of MyD88/CD40 Drives In Vivo Activation and Proliferation of Chimeric Antigen Receptor-Modified T Cells That Can be Effectively Regulated By Inducible Caspase-9

Aaron Foster, PhD, Peter Chang, PhD, Pei-Yi Lin, PhD, Jeannette Crisostomo, Aruna Mahendravada, An Lu, Mariam Khalil, Sunandan Saha, PhD, Joanne Shaw, PhD, Eva Morschl, PhD, Kevin M Slawin, MD, David M Spencer, PhD

Blood (2015) 126 (23): 851.

https://doi.org/10.1182/blood.V126.23.851.851

Published: 2015

Journal Articles

Inducible MyD88/CD40 Allows AP1903-Dependent Costimulation to Control Proliferation and Survival of Chimeric Antigen Receptor-Modified T Cells

Aaron Foster, PhD, Aruna Mahendravada, Peter Chang, PhD, Nicholas Shinners, PhD, Kevin Slawin, MD, David Spencer, PhD

Blood (2014) 124 (21): 1121.

https://doi.org/10.1182/blood.V124.21.1121.1121

Published: 2014

Journal Articles

Selective Loss of a Putative Precursor Population of B-Chronic Lymphocytic Leukemia Cells Following Immunization with hCD40L/IL-2 Expressing Autologous Tumor Cells

Aaron Foster, PhD, Fatma Okur, MD, Gianpietro Dotti, MD, Jessica Shafer, MD, An Lu, Ettore Biagi, Eric Yvon, Catherine M Bollard, MD, Barbara Savoldo, MD, Michael Andreeff, MD, PhD, Margaret A Goodell, PhD, Cliona M Rooney, PhD, Malcolm K Brenner, MD, PhD

Blood (2008) 112 (11): 3172.

https://doi.org/10.1182/blood.V112.11.3172.3172

Published: 2008

Journal Articles

The “Side-Population” of Human Lymphoma Cells Have Increased Chemo-Resistance, Stem-Cell Like Properties and Are Potential Targets for Immunotherapy

Jessica Ann Shafer, M.D., Ann M. Leen, PhD, Conrad Russell Cruz, John A Craddock, M.D., Helen E. Heslop, M.D., Cliona M. Rooney, PhD, Malcolm K Brenner, MD, PhD, Catherine M. Bollard, MD, FRACP, FRCPA, Aaron Foster, PhD

Blood (2008) 112 (11): 2620.

https://doi.org/10.1182/blood.V112.11.2620.2620

Published: 2008

NARROW

Regulated Natural Killer Cell Expansion and Anti-Tumor Activity with Inducible MyD88/CD40

A Simplified Method for Transduction and Expansion of T Cells for Clinical Application

T- and B-Cell Neogenesis Recovers Efficiently in Children with Acute Leukemia Given an Alpha-Beta T-Cell Depleted Haplo-HSCT Followed By Infusion of Donor T-Cells Genetically Modified with Inducible Caspase 9 Suicide Gene (BPX-501 cells)

Characterization of Allogeneic T Cells Expressing Inducible Caspase-9 Following Adoptive Transfer in Children Receiving an HLA-Haploidentical Hematopoietic Stem Cell Transplant for the Treatment of Myeloid Malignancies

Differential Expression of Inducible Caspase-9 (iC9) in Allogeneic T Cells Allows Selective Depletion of Activated T Cells Following Exposure to Rimiducid and Permits In Vivo Allodepletion

Inducible MyD88/CD40 Enhances Proliferation and Survival of PRAME-Specific TCR-Engineered T Cells and Increases Anti-Tumor Effects in Myeloma

Inducible MyD88/CD40 Allows Rimiducid-Dependent Activation to Control Proliferation and Survival of Chimeric Antigen Receptor-Modified T Cells

Expression of MyD88/CD40 Drives In Vivo Activation and Proliferation of Chimeric Antigen Receptor-Modified T Cells That Can be Effectively Regulated By Inducible Caspase-9

Inducible MyD88/CD40 Allows AP1903-Dependent Costimulation to Control Proliferation and Survival of Chimeric Antigen Receptor-Modified T Cells

Selective Loss of a Putative Precursor Population of B-Chronic Lymphocytic Leukemia Cells Following Immunization with hCD40L/IL-2 Expressing Autologous Tumor Cells

The “Side-Population” of Human Lymphoma Cells Have Increased Chemo-Resistance, Stem-Cell Like Properties and Are Potential Targets for Immunotherapy

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ASH Publications

American Society of Hematology

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ASH Publications

American Society of Hematology

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