In six out of seven polycythemic patients treated with radiophosphorus a significant decrease of the proaccelerin content of the plasma was observed.

This diminution began to become detectable by means of semiquantitative estimations on the second day after the radioactive isotope was given and lasted for three to sixteen days.

The degree of the deficiency seemed to depend on the amount of radiophosphorus administered, only the highest dose having been capable of impairing the coagulation severely.

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© 1954 by American Society of Hematology, Inc.
1954
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