Cytogenetic studies of the bone marrow and peripheral blood with the quinacrine fluorescence banding technique in a patient with the clinical diagnosis of acute myeloblastic leukemia revealed the Philadelphia chromosome due to a translocation between chromosomes 22 and 9. He had been exposed to the atomic bomb in Hiroshima, and some hours after the exposure he wandered into the hypocenter.

Topics:
leukemia, myelocytic, acute, philadelphia chromosome, translocation (genetics), clinical diagnosis, quinacrine, bone marrow, fluorescence
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Copyright © 1977 by The American Society of Hematology
1977
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